-
1
-
-
0027239503
-
Antitumor and antimetastatic activity of interleukin 12 against murine tumors
-
Brunda MJ, Luistro L, Warrier RR et al: Antitumor and antimetastatic activity of interleukin 12 against murine tumors. J Exp Med 178: 1223-1230, 1993.
-
(1993)
J Exp Med
, vol.178
, pp. 1223-1230
-
-
Brunda, M.J.1
Luistro, L.2
Warrier, R.R.3
-
2
-
-
0027963161
-
Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production
-
Nastala CL, Edington HD, McKinney TG et al: Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. J Immunol 153: 1697-1706, 1994.
-
(1994)
J Immunol
, vol.153
, pp. 1697-1706
-
-
Nastala, C.L.1
Edington, H.D.2
McKinney, T.G.3
-
3
-
-
0024467154
-
Identification and purification of natural-killer cell stimulatory factor (Nksf), a cytokine with multiple biologic effects on human-lymphocytes
-
Kobayashi M, Fitz L, Ryan M et al: Identification and purification of natural-killer cell stimulatory factor (Nksf), a cytokine with multiple biologic effects on human-lymphocytes. J Exp Med 170: 827-845, 1989.
-
(1989)
J Exp Med
, vol.170
, pp. 827-845
-
-
Kobayashi, M.1
Fitz, L.2
Ryan, M.3
-
4
-
-
0025873502
-
Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor)
-
Gately MK, Desai BB, Wolitzky AG et al: Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). J Immunol 147: 874-882, 1991.
-
(1991)
J Immunol
, vol.147
, pp. 874-882
-
-
Gately, M.K.1
Desai, B.B.2
Wolitzky, A.G.3
-
5
-
-
0028043326
-
Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes
-
Trinchieri G: Interleukin-12: A cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes. Blood 84: 4008-4027, 1994.
-
(1994)
Blood
, vol.84
, pp. 4008-4027
-
-
Trinchieri, G.1
-
6
-
-
0028012527
-
Interleukin-12
-
Brunda MJ: Interleukin-12. J Leukoc Biol 55: 280-288, 1994.
-
(1994)
J Leukoc Biol
, vol.55
, pp. 280-288
-
-
Brunda, M.J.1
-
7
-
-
0028987027
-
Interleukin 12: A new clinical player in cytokine therapy
-
Banks RE, Patel PM and Selby PJ: Interleukin 12: a new clinical player in cytokine therapy. Br J Cancer 71: 655-659, 1995.
-
(1995)
Br J Cancer
, vol.71
, pp. 655-659
-
-
Banks, R.E.1
Patel, P.M.2
Selby, P.J.3
-
9
-
-
0029922177
-
Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10
-
Sgadari C, Angiolillo AL and Tosato G: Inhibition of angiogenesis by interleukin-12 is mediated by the interferon-inducible protein 10. Blood 87: 3877-3882, 1996.
-
(1996)
Blood
, vol.87
, pp. 3877-3882
-
-
Sgadari, C.1
Angiolillo, A.L.2
Tosato, G.3
-
10
-
-
0031001933
-
Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo
-
Sgadari C, Farber JM, Angiolillo AL et al: Mig, the monokine induced by interferon-gamma, promotes tumor necrosis in vivo. Blood 89: 2635-2643, 1997.
-
(1997)
Blood
, vol.89
, pp. 2635-2643
-
-
Sgadari, C.1
Farber, J.M.2
Angiolillo, A.L.3
-
11
-
-
0031656897
-
Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12
-
Kanegane C, Sgadari C, Kanegane H et al: Contribution of the CXC chemokines IP-10 and Mig to the antitumor effects of IL-12. J Leukoc Biol 64: 384-392, 1998.
-
(1998)
J Leukoc Biol
, vol.64
, pp. 384-392
-
-
Kanegane, C.1
Sgadari, C.2
Kanegane, H.3
-
12
-
-
0032528446
-
The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor
-
Tannenbaum CS, Tubbs R, Armstrong D et al: The CXC chemokines IP-10 and Mig are necessary for IL-12-mediated regression of the mouse RENCA tumor. J Immunol 161: 927-932, 1998.
-
(1998)
J Immunol
, vol.161
, pp. 927-932
-
-
Tannenbaum, C.S.1
Tubbs, R.2
Armstrong, D.3
-
13
-
-
0031000838
-
Regulation of local host-mediated anti-tumor mechanisms by cytokines: Direct and indirect effects on leukocyte recruitment and angiogenesis
-
Watanabe M, McCormick KL, Volker K et al: Regulation of local host-mediated anti-tumor mechanisms by cytokines: direct and indirect effects on leukocyte recruitment and angiogenesis. Am J Pathol 150: 1869-1880, 1997.
-
(1997)
Am J Pathol
, vol.150
, pp. 1869-1880
-
-
Watanabe, M.1
McCormick, K.L.2
Volker, K.3
-
14
-
-
0032521153
-
Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis
-
Coughlin CM, Salhany KE, Wysocka M et al: Interleukin-12 and interleukin-18 synergistically induce murine tumor regression which involves inhibition of angiogenesis. J Clin Invest 101: 1441-1452, 1998.
-
(1998)
J Clin Invest
, vol.101
, pp. 1441-1452
-
-
Coughlin, C.M.1
Salhany, K.E.2
Wysocka, M.3
-
15
-
-
0033214696
-
Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12
-
Gee MS, Koch CJ, Evans SM et al: Hypoxia-mediated apoptosis from angiogenesis inhibition underlies tumor control by recombinant interleukin 12. Cancer Res 59: 4882-4889, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 4882-4889
-
-
Gee, M.S.1
Koch, C.J.2
Evans, S.M.3
-
16
-
-
0033104852
-
Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12
-
Yao L, Sgadari C, Furuke K et al: Contribution of natural killer cells to inhibition of angiogenesis by interleukin-12. Blood 93: 1612-1621, 1999.
-
(1999)
Blood
, vol.93
, pp. 1612-1621
-
-
Yao, L.1
Sgadari, C.2
Furuke, K.3
-
17
-
-
0034284301
-
Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12
-
Yao L, Pike SE, Setsuda J et al: Effective targeting of tumor vasculature by the angiogenesis inhibitors vasostatin and interleukin-12. Blood 96: 1900-1905, 2000.
-
(2000)
Blood
, vol.96
, pp. 1900-1905
-
-
Yao, L.1
Pike, S.E.2
Setsuda, J.3
-
18
-
-
0034070283
-
Potentiated antitumor effects of interleukin 12 and matrix metalloproteinase inhibitor batimastat against B16F10 melanoma in mice
-
Dabrowska A, Giermasz A, Marczak M et al: Potentiated antitumor effects of interleukin 12 and matrix metalloproteinase inhibitor batimastat against B16F10 melanoma in mice. Anticancer Res 20: 391-394, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 391-394
-
-
Dabrowska, A.1
Giermasz, A.2
Marczak, M.3
-
19
-
-
0034652459
-
Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12
-
Duda DG, Sunamura M, Lozonschi L et al: Direct in vitro evidence and in vivo analysis of the antiangiogenesis effects of interleukin 12. Cancer Res 60: 1111-1116, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 1111-1116
-
-
Duda, D.G.1
Sunamura, M.2
Lozonschi, L.3
-
20
-
-
0033556011
-
Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12
-
Cavallo F, Di Carlo E, Butera M et al: Immune events associated with the cure of established tumors and spontaneous metastases by local and systemic interleukin 12. Cancer Res 59: 414-421, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 414-421
-
-
Cavallo, F.1
Di Carlo, E.2
Butera, M.3
-
21
-
-
0034649786
-
Ability of systemic interleukin-12 to hamper progressive stages of mammary carcinogenesis in HER2/neu transgenic mice
-
Boggio K, Di Carlo E, Rovero S et al. Ability of systemic interleukin-12 to hamper progressive stages of mammary carcinogenesis in HER2/neu transgenic mice. Cancer Res 60: 359-364, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 359-364
-
-
Boggio, K.1
Di Carlo, E.2
Rovero, S.3
-
22
-
-
0032904888
-
Transfer of the murine interleukin-12 gene in vivo by a Semliki Forest virus vector induces B16 tumor regression through inhibition of tumor blood vessel formation monitored by Doppler ultrasonography
-
Asselin-Paturel C, Lassau N, Guinebretiere JM et al: Transfer of the murine interleukin-12 gene in vivo by a Semliki Forest virus vector induces B16 tumor regression through inhibition of tumor blood vessel formation monitored by Doppler ultrasonography. Gene Ther 5: 606-615, 1998.
-
(1998)
Gene Ther
, vol.5
, pp. 606-615
-
-
Asselin-Paturel, C.1
Lassau, N.2
Guinebretiere, J.M.3
-
23
-
-
0042025067
-
Pharmacokinetics and immunological aspects of a phase Ib study with intratumoral administration of recombinant human Interleukin-12 in patients with head and neck squamous cell carcinoma: A decrease of T-bet in PBMCs
-
van Herpen CM, Huijbens R, Looman M et al: Pharmacokinetics and immunological aspects of a phase Ib study with intratumoral administration of recombinant human Interleukin-12 in patients with head and neck squamous cell carcinoma: a decrease of T-bet in PBMCs. Clin Cancer Res 9: 2950-2956, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2950-2956
-
-
Van Herpen, C.M.1
Huijbens, R.2
Looman, M.3
-
24
-
-
0028785458
-
Evidence that hypoxia markers detect oxygen gradients in liver - Pimonidazole and retrograde perfusion of rat-liver
-
Arteel GE, Thurman RG, Yates JM et al: Evidence that hypoxia markers detect oxygen gradients in liver - pimonidazole and retrograde perfusion of rat-liver. Br J Cancer 72: 889-895, 1995.
-
(1995)
Br J Cancer
, vol.72
, pp. 889-895
-
-
Arteel, G.E.1
Thurman, R.G.2
Yates, J.M.3
-
25
-
-
0032801526
-
Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors
-
Raleigh JA, Chou SC, Arteel GE et al. Comparisons among pimonidazole binding, oxygen electrode measurements, and radiation response in C3H mouse tumors. Radiation Res 151: 580-589, 1999.
-
(1999)
Radiation Res
, vol.151
, pp. 580-589
-
-
Raleigh, J.A.1
Chou, S.C.2
Arteel, G.E.3
-
26
-
-
8544221117
-
Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential
-
Westphal JR, vantHullenaar RGM, vanderLaak JAWM et al. Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential. Br J Cancer 76: 561-570, 1997.
-
(1997)
Br J Cancer
, vol.76
, pp. 561-570
-
-
Westphal, J.R.1
VantHullenaar, R.G.M.2
VanderLaak, J.A.W.M.3
-
27
-
-
0021993734
-
Inhibition of mixed lymphocyte-response by a rat monoclonal-antibody to a novel murine lymphocyte-activation antigen (Mala-2)
-
Takei F: Inhibition of mixed lymphocyte-response by a rat monoclonal-antibody to a novel murine lymphocyte-activation antigen (Mala-2). J Immunol 134: 1403-1407, 1985.
-
(1985)
J Immunol
, vol.134
, pp. 1403-1407
-
-
Takei, F.1
-
28
-
-
0032944785
-
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts, effects of carbogen and nicotinamide
-
Bussink J, Kaanders JHAM, Rijken PFJW et al. Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts, effects of carbogen and nicotinamide. Radiother Oncol 50: 173-184, 1999.
-
(1999)
Radiother Oncol
, vol.50
, pp. 173-184
-
-
Bussink, J.1
Kaanders, J.H.A.M.2
Rijken, P.F.J.W.3
-
29
-
-
0034265986
-
Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: A quantitative multi-parameter analysis
-
Rijken PFJW, Bernsen HJJA, Peters JPW et al. Spatial relationship between hypoxia and the (perfused) vascular network in a human glioma xenograft: A quantitative multi-parameter analysis. Int J Radiat Oncol Biol Phys 48: 571-582, 2000.
-
(2000)
Int J Radiat Oncol Biol Phys
, vol.48
, pp. 571-582
-
-
Rijken, P.F.J.W.1
Bernsen, H.J.J.A.2
Peters, J.P.W.3
-
30
-
-
0029150035
-
Application of an image-analysis system to the quantitation of tumor perfusion and vascularity in human glioma xenografts
-
Rijken PFJW, Bernsen HJJA, van der Kogel AJ. Application of an image-analysis system to the quantitation of tumor perfusion and vascularity in human glioma xenografts. Microvascular Res 1950: 141-153, 1995.
-
(1995)
Microvascular Res
, vol.1950
, pp. 141-153
-
-
Rijken, P.F.J.W.1
Bernsen, H.J.J.A.2
Van Der Kogel, A.J.3
-
31
-
-
0018332721
-
Nude Mice in immunology
-
Kindred, B. Nude Mice in immunology. Prog Allergy 26: 137-238, 1979.
-
(1979)
Prog Allergy
, vol.26
, pp. 137-238
-
-
Kindred, B.1
-
32
-
-
0035869599
-
IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk
-
Strasly M, Cavallo F, Geuna M et al: IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk. J Immunol 766: 3890-3899, 2001.
-
(2001)
J Immunol
, vol.766
, pp. 3890-3899
-
-
Strasly, M.1
Cavallo, F.2
Geuna, M.3
-
33
-
-
0034035122
-
Protective immunity is induced in murine colon carcinoma cells by the expression of interleukin-12 or interleukin-18, which activate type 1 helper T cells
-
Tasaki K, Yoshida Y, Maeda T et al: Protective immunity is induced in murine colon carcinoma cells by the expression of interleukin-12 or interleukin-18, which activate type 1 helper T cells. Cancer Gene Ther 7: 247-254, 2000.
-
(2000)
Cancer Gene Ther
, vol.7
, pp. 247-254
-
-
Tasaki, K.1
Yoshida, Y.2
Maeda, T.3
-
34
-
-
0033119468
-
A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression
-
Ogawa M, Umehara K, Yu WG et al: A critical role for a peritumoral stromal reaction in the induction of T-cell migration responsible for interleukin-12-induced tumor regression. Cancer Res 59: 1531-1538, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 1531-1538
-
-
Ogawa, M.1
Umehara, K.2
Yu, W.G.3
-
35
-
-
0034164561
-
The development of peritumoral stroma required for IL-12 induced tumor regression depends on the T cell/IFN-gamma-involving host-tumor interaction
-
Uekusa Y, Ogawa M, Gao P et al: The development of peritumoral stroma required for IL-12 induced tumor regression depends on the T cell/IFN-gamma-involving host-tumor interaction. Int J Oncol 16: 805-814, 2000.
-
(2000)
Int J Oncol
, vol.16
, pp. 805-814
-
-
Uekusa, Y.1
Ogawa, M.2
Gao, P.3
-
36
-
-
0037223555
-
Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy
-
Gee MS, Procopio WN, Makonnen S et al: Tumor vessel development and maturation impose limits on the effectiveness of anti-vascular therapy. Am J Pathol 162: 183-193, 2003.
-
(2003)
Am J Pathol
, vol.162
, pp. 183-193
-
-
Gee, M.S.1
Procopio, W.N.2
Makonnen, S.3
-
37
-
-
0036468547
-
Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas
-
Lee JC, Kim DC, Gee MS et al: Interleukin-12 inhibits angiogenesis and growth of transplanted but not in situ mouse mammary tumor virus-induced mammary carcinomas. Cancer Res 62: 747-755, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 747-755
-
-
Lee, J.C.1
Kim, D.C.2
Gee, M.S.3
|