Colon cancer: Molecular markers;Kolonkarzinom: Molekulare marker

Deutsche Medizinische Wochenschrift

Volumn 130, Issue 14, 2005, Pages 880-882

  Arnold, Christian N ^a   Blum, H E ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MOLECULAR MARKER; TUMOR MARKER;

CANCER DIAGNOSIS; CANCER INCIDENCE; CANCER MORTALITY; CHROMOSOMAL INSTABILITY; COLON CANCER; COLONOSCOPY; COLORECTAL CARCINOMA; DISEASE MARKER; HUMAN; MICROSATELLITE INSTABILITY; POLYMERASE CHAIN REACTION; PROGNOSIS; REVIEW;

ANTIMETABOLITES, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CAMPTOTHECIN; CLINICAL TRIALS; COLORECTAL NEOPLASMS; DNA REPAIR; DNA, NEOPLASM; FECES; FLUOROURACIL; GENES, RAS; GENES, TUMOR SUPPRESSOR; GENETIC MARKERS; HUMANS; MICROSATELLITE REPEATS; MUTATION; ONCOGENES; POLYMERASE CHAIN REACTION; PROGNOSIS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TREATMENT OUTCOME; TUMOR CELLS, CULTURED; TUMOR MARKERS, BIOLOGICAL;

EID: 17444418601     PISSN: 00120472     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-865102     Document Type: Review

References (15)

1. Ahlquist DA, Skoletsky JE, Boynton KA et al. Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel. Gastroenterology 2000; 119: 1219-1227
2. Arnold CN, Blum HE. Molekulare Pathogenese des Kolonkarzinoms: Klinische Relevanz. Dtsch Med Wochenschr 2005; 130: 809-811 (Teil 1 dieses Beitrages)
3. Arnold CN, Goel A, Boland CR. Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines. Int J Cancer 2003; 106: 66-73
4. Barratt PL, Seymour MT, Stenning SP et al. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study. Lancet 2002; 360: 1381-1391
5. Calistri D, Rengucci C, Bocchini R, Saragoni L, Zloi W, Amadori D. Fecal multiple molecular tests to detect colorectal cancer in stool. Clin Gastro Hepatol 2003; 1: 377-383
6. Carethers JM, Smith EJ, Behing CA et al. Use of 5-fluorouracil and survival in patients with microsatellite unstable colorectal cancer. Gastroenterology 2004; 126: 394-401
7. Dong SM, Traverse G, Johnson C et al. Detecting colorectal cancer in stool with the use of multiple genetic targets. J Natl Cancer Inst 2001; 93: 858-865
8. Fallik D, Borrini F, Boige V et al. Microsatellite instability is a predictive factor of the tumor response to irinotecan in patients with advanced colorectal cancer. Cancer Res 2003; 63: 5738-5744
9. Müller HM, Oberwalder M, Fiegl H et al. Methylaion changes in faecal DNA: a marker for colorectal screenng? Lancet 2004; 363: 1283-1285
10. Ribic CM, Sargent DJ, Moore MJ et al. Tumor microsatellite-instability status as a predictor of benefit from fluorouracil-based adjuvant chemotherapy for colon cancer. N Engl J Med 2003; 349: 247-257
11. Sidransky D, Tokino T, Hamilton SR et al. Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992; 256: 102-105
12. Traverse G, Shuber A, Levin B et al. Detection of APC mutations in fecal DNA from patients with colorectal tumors. N Engl J Med 2002; 346: 311-320
13. Traverse G, Shuber A, Olsson L et al. Detection of proximal colorectal cancers through analysis of faecal DNA. Lancet 2002; 359: 403-404
14. Watanabe T, Wu TT, Catalane PJ et al. Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 2001; 344: 1196-1206
15. Zhou W, Goodman SN, Galizia G et al. Counting alleles to predict recurrence of early-stage colorectal cancers. Lancet 2002; 359: 219-225