Reevaluation of amino acid stimulation of protein synthesis in murine- and human-derived skeletal muscle cells assessed by independent techniques

American Journal of Physiology - Endocrinology and Metabolism

Volumn 288, Issue 5 51-5, 2005, Pages

  Iresjö, Britt Marie ^a   Svanberg, Elisabeth ^a   Lundholm, Kent ^a  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Amino acids; Initiation of translation; Insulin; Muscle cells; Protein synthesis

Indexed keywords

AMINO ACID; BRANCHED CHAIN AMINO ACID; CELL PROTEIN; GLUTAMINE; INITIATION FACTOR; METHIONINE; PHENYLALANINE; RNA; TYROSINE;

ANIMAL TISSUE; ARTICLE; CELL CULTURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; GASTROCNEMIUS MUSCLE; METHODOLOGY; MOUSE; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; QUALITATIVE ANALYSIS; RHABDOMYOSARCOMA; RNA TRANSLATION; SKELETAL MUSCLE; STARVATION; TRANSLATION INITIATION; WESTERN BLOTTING;

ADMINISTRATION, ORAL; AMINO ACIDS; ANIMALS; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; MICE; MUSCLE FIBERS; MUSCLE PROTEINS;

EID: 17444392446     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00295.2004     Document Type: Article

References (53)

1. Abumrad NN, Williams P, Frexes-Steed M, Geer R, Flakoll P, Cersosimo E, Brown LL, Melki I, Bulus N, Hourani H, Hubbard M, and Ghishan F. Inter-organ metabolism of amino acids in vivo. Diabetes Metab Rev 5: 213-226, 1989.
2. Balage M, Sinaud S, Prod'homme M, Dardevet D, Vary TC, Kimball SR, Jefferson LS, and Grizard J. Amino acids and insulin are both required to regulate assembly of the eIF4E-eIF4G complex in rat skeletal muscle. Am J Physiol Endocrinol Metab 281: E565-E574, 2001.
3. Barnes DM, Calvert CC, and Klasing KC. Methionine deficiency decreases protein accretion and synthesis but not tRNA acylation in muscles of chicks. J Nutr 125: 2623-2630, 1995.
4. Barnes DM, Calvert CC, and Klasing KC. Source of amino acids for tRNA acylation. Implications for measurement of protein synthesis. Biochem J 283: 583-589, 1992.
5. Bennegard K, Eden E, Ekman L, Schersten T, and Lundholm K. Metabolic response of whole body and peripheral tissues to enteral nutrition in weight-losing cancer and noncancer patients. Gastroenterology 85: 92-99, 1983.
6. Bennegard K, Lindmark L, Eden E, Svaninger G, and Lundholm K. Flux of amino acids across the leg in weight-losing cancer patients. Cancer Res 44: 386-393, 1984.
7. Bohe J, Low A, Wolfe RR, and Rennie MJ. Human muscle protein synthesis is modulated by extracellular, not intramuscular amino acid availability: a dose-response study. J Physiol 552: 315-324, 2003.
8. Borsheim E, Tipton KD, Wolf SE, and Wolfe RR. Essential amino acids and muscle protein recovery from resistance exercise. Am J Physiol Endocrinol Metab 283: E648-E657, 2002.
9. Brodsky IG, Suzara D, Hornberger TA, Goldspink P, Yarasheski KE, Smith S, Kukowski J, Esser K, and Bedno S. Isoenergetic dietary protein restriction decreases myosin heavy chain IIx fraction and myosin heavy chain production in humans. J Nutr 134: 328-334, 2004.
10. Caso G, Ford GC, Nair KS, Vosswinkel JA, Garlick PJ, and McNurlan MA. Increased concentration of tracee affects estimates of muscle protein synthesis. Am J Physiol Endocrinol Metab 280: E937-E946, 2001.
11. Cooney RN, Kimball SR, and Vary TC. Regulation of skeletal muscle protein turnover during sepsis: mechanisms and mediators. Shock 7: 1-16, 1997.
12. Davis TA, Fiorotto ML, Nguyen HV, and Burrin DG. Aminoacyl-tRNA and tissue free amino acid pools are equilibrated after a flooding dose of phenylalanine. Am J Physiol Endocrinol Metab 277: E103-E109, 1999.
13. De Blaauw I, Heeneman S, Deutz NE, and von Meyenfeldt MF. Increased whole-body protein and glutamine turnover in advanced cancer is not matched by an increased muscle protein and glutamine turnover. J Surg Res 68: 44-55, 1997.
14. Flaim KE, Liao WS, Peavy DE, Taylor JM, and Jefferson LS. The role of amino acids in the regulation of protein synthesis in perfused rat liver. II. Effects of amino acid deficiency on peptide chain initiation, polysomal aggregation, and distribution of albumin mRNA. J Biol Chem 257: 2939-2946, 1982.
15. Fouladiun M, Körner U, Bosaeus I, Daneryd P, Hyltander A, and lundholm K. Body composition and time course changes in regional distribution of fat and lean tissues in unselected cancer patients on palliative care: relationships to food intake, metabolism, exercise capacity and hormones. Cancer. In press.
16. Garlick PJ and Grant I. Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin: effect of branched-chain amino acids. Biochem J 254: 579-584, 1988.
17. Garlick PJ and McNurlan MA. Measurement of protein synthesis in human tissues by the flooding method. Curr Opin Clin Nutr Metab Care 1: 455-460, 1998.
18. Garlick PJ, McNurlan MA, and Preedy VR. A rapid and convenient technique for measuring the rate of protein synthesis in tissues by injection of [3H]phenylalanine. Biochem J 192: 719-723, 1980.
19. Greiwe JS, Kwon G, McDaniel ML, and Semenkovich CF. Leucine and insulin activate p70 S6 kinase through different pathways in human skeletal muscle. Am J Physiol Endocrinol Metab 281: E466-E471, 2001.
20. Hyltander A, Warnold I, Eden E, and Lundholm K. Effect on whole-body protein synthesis after institution of intravenous nutrition in cancer and non-cancer patients who lose weight. Eur J Cancer 27: 16-21, 1991.
21. Kimball SR. Regulation of global and specific mRNA translation by amino acids. J Nutr 132: 883-886, 2002.
22. Kimball SR, Farrell PA, Nguyen HV, Jefferson LS, and Davis TA. Developmental decline in components of signal transduction pathways regulating protein synthesis in pig muscle. Am J Physiol Endocrinol Metab 282: E585-E592, 2002.
23. Kimball SR, Horetsky RL, and Jefferson LS. Implication of eIF2B rather than eIF4E in the regulation of global protein synthesis by amino acids in L6 myoblasts. J Biol Chem 273: 30945-30953, 1998.
24. Kimball SR and Jefferson LS. Regulation of global and specific mRNA translation by oral administration of branched-chain amino acids. Biochem Biophys Res Commun 313: 423-427, 2004.
25. Kleijn M, Scheper GC, Voorma HO, and Thomas AA. Regulation of translation initiation factors by signal transduction. Eur J Biochem 253: 531-544, 1998.
26. Liu Z, Jahn LA, Wei L, Long W, and Barrett EJ. Amino acids stimulate translation initiation and protein synthesis through an Akt-independent pathway in human skeletal muscle. J Clin Endocrinol Metab 87: 5553-5558, 2002.
27. Ljungqvist OH, Persson M, Ford GC, and Nair KS. Functional heterogeneity of leucine pools in human skeletal muscle. Am J Physiol Endocrinol Metab 273: E564-E570, 1997.
28. Long W, Saffer L, Wei L, and Barrett EJ. Amino acids regulate skeletal muscle PHAS-I and p70 S6-kinase phosphorylation independently of insulin. Am J Physiol Endocrinol Metab 279: E301-E306, 2000.
29. Lundholm K, Bennegard K, Zachrisson H, Lundgren F, Eden E, and Moller-Loswick AC. Transport kinetics of amino acids across the resting human leg. J Clin Invest 80: 763-771, 1987.
30. Lundholm K, Edstrom S, Ekman L, Karlberg I, and Schersten T. Metabolism in peripheral tissues in cancer patients. Cancer Treat Res 65: 79-83, 1981.
31. Lundholm K and Schersten T. Incorporation of leucine into human skeletal muscle proteins. A study of tissue amino acid pool and their role in protein biosynthesis. Acta Physiol Scand 93: 433-441, 1975.
32. Lundholm K and Schersten T. Protein synthesis in human skeletal muscle tissue: influence of insulin and amino acids. Eur J Clin Invest 7: 531-536, 1977.
33. Lundholm K, Ternell M, Zachrisson H, Moldawer L, and Lindstrom L. Measurement of hepatic protein synthesis in unrestrained mice- evaluation of the "flooding technique." Acta Physiol Scand 141: 207-219, 1991.
34. Lynch CJ, Hutson SM, Patson BJ, Vaval A, and Vary TC. Tissue-specific effects of chronic dietary leucine and norleucine supplementation on protein synthesis in rats. Am J Physiol Endocrinol Metab 283: E824-E835, 2002.
35. Millward DJ, Garlick PJ, Nnanyelugo DO, and Waterlow JC. The relative importance of muscle protein synthesis and breakdown in the regulation of muscle mass. Biochem J 156: 185-188, 1976.
36. Moller-Loswick AC, Zachrisson H, Bennegard K, Sandstrom R, and Lundholm K. Insufficient effect of total parenteral nutrition to improve protein balance in peripheral tissues of surgical patients. J Parenter Enteral Nutr 15: 669-675, 1991.
37. Morgan HE, Jefferson LS, Wolpert EB, and Rannels DE. Regulation of protein synthesis in heart muscle. II. Effect of amino acid levels and insulin on ribosomal aggregation. J Biol Chem 246: 2163-2170, 1971.
38. Pain VM. Initiation of protein synthesis in eukaryotic cells. Eur J Biochem 236: 747-771, 1996.
39. Pardridge WM, Davidson MB, and Casanello-Ertl D. Glucose and amino acid metabolism in an established line of skeletal muscle cells. J Cell Physiol 96: 309-318, 1978.
40. Preedy VR and Garlick PJ. The response of muscle protein synthesis to nutrient intake in postabsorptive rats: the role of insulin and amino acids. Biosci Rep 6: 177-183, 1986.
41. Rasmussen BB, Wolfe RR, and Volpi E. Oral and intravenously administered amino acids produce similar effects on muscle protein synthesis in the elderly. J Nutr Health Aging 6: 358-362, 2002.
42. Rennie MJ, Bohe J, and Wolfe RR. Latency, duration and dose response relationships of amino acid effects on human muscle protein synthesis. J Nutr 132: 3225S-3227S, 2002.
43. Smith CB and Sun Y. Influence of valine flooding on channeling of valine into tissue pools and on protein synthesis. Am J Physiol Endocrinol Metab 268: E735-E744, 1995.
44. Svanberg E, Jefferson LS, Lundholm K, and Kimball SR. Postprandial stimulation of muscle protein synthesis is independent of changes in insulin. Am J Physiol Endocrinol Metab 272: E841-E847, 1997.
45. Svanberg E, Moller-Loswick AC, Matthews DE, Korner U, Andersson M, and Lundholm K. The role of glucose, long-chain triglycerides and amino acids for promotion of amino acid balance across peripheral tissues in man. Clin Physiol 19: 311-320, 1999.
46. Svanberg E, Moller-Loswick AC, Matthews DE, Korner U, and Lundholm K. The effect of glutamine on protein balance and amino acid flux across arm and leg tissues in healthy volunteers. Clin Physiol 21: 478-489, 2001.
47. Svanberg E, Ohlsson C, Hyltander A, and Lundholm KG. The role of diet components, gastrointestinal factors, and muscle innervation on activation of protein synthesis in skeletal muscles following oral refeeding. Nutrition 15: 257-266, 1999.
48. Svanberg E, Zachrisson H, Ohlsson C, Iresjo BM, and Lundholm KG. Role of insulin and IGF-I in activation of muscle protein synthesis after oral feeding. Am J Physiol Endocrinol Metab 270: E614-E620, 1996.
49. Vary TC, Jefferson LS, and Kimball SR. Amino acid-induced stimulation of translation initiation in rat skeletal muscle. Am J Physiol Endocrinol Metab 277: E1077-E1086, 1999.
50. Warnold I, Eden E, and Lundholm K. The inefficiency of total parenteral nutrition to stimulate protein synthesis in moderately malnourished patients. Ann Surg 208: 143-149, 1988.
51. Waterlow JC, Garlick PJ, and Millward DJ. Protein Turnover in Mammalian Tissues and in the Whole Body. Amsterdam: Elsevier, 1978.
52. Watt PW, Corbett ME, and Rennie MJ. Stimulation of protein synthesis in pig skeletal muscle by infusion of amino acids during constant insulin availability. Am J Physiol Endocrinol Metab 263: E453-E460, 1992.
53. Yaffe D. Retention of differentiation potentialities during prolonged cultivation of myogenic cells. Proc Natl Acad Sci USA 61: 477-483, 1968.