Investigation of the effect of brain-derived neurotrophic factor (BDNF) polymorphisms on the risk of late-onset Alzheimer's disease (AD) and quantitative measures of AD progression

Neuroscience Letters

Volumn 379, Issue 3, 2005, Pages 229-234

  Desai, Purnima ^a   Nebes, Robert ^b   DeKosky, Steven T ^a,b   Kamboh, M Ilyas ^a,b  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; BDNF; Polymorphism

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

AFRICAN AMERICAN; AGED; ALLELE; ALZHEIMER DISEASE; ARTICLE; CHROMOSOME NOR; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE CARRIER; DISEASE COURSE; DNA POLYMORPHISM; FEMALE; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MINI MENTAL STATE EXAMINATION; NUCLEOTIDE SEQUENCE; ONSET AGE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SCORING SYSTEM; STATISTICAL SIGNIFICANCE; UNINDEXED SEQUENCE;

EID: 17444388945     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2005.01.008     Document Type: Article

References (31)

1. S. Bagnoli, B. Nacmias, A. Tedde, B.M. Guarnieri, E. Cellini, C. Petruzzi, A. Bartoli, L. Ortenzi, and S. Sorbi Brain-derived neurotrophic factor genetic variants are not susceptibility factors to Alzheimer's disease in Italy Ann. Neurol. 55 2004 447 448
2. O. Combarros, J. Infante, J. Llorca, and J. Berciano Polymorphism at codon 66 of the brain-derived neurotrophic factor gene is not associated with sporadic Alzheimer's disease Dement. Geriatr. Cogn. Disord. 18 2004 55 58
3. B. Connor, D. Young, Q. Yan, R.L. Faull, B. Synek, and M. Dragunow Brain-derived neurotrophic factor is reduced in Alzheimer's disease Brain Res. Mol. Brain Res. 49 1997 71 81
4. E.H. Corder, A.M. Saunders, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskell, G.W. Small, A.D. Roses, J.L. Haines, and M.A. Pericak-Vance Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 1993 921 923
5. M.F. Egan, M. Kojima, J.H. Callicott, T.E. Goldberg, B.S. Kolachana, A. Bertolino, E. Zaitsev, B. Gold, D. Goldman, M. Dean, B. Lu, and D.R. Weinberger The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function Cell 112 2003 257 269
6. I. Ferrer, C. Marin, M.J. Rey, T. Ribalta, E. Goutan, R. Blanco, E. Tolosa, and E. Marti BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies J. Neuropathol. Exp. Neurol. 58 1999 729 739
7. M.F. Folstein, S.E. Folstein, and P.R. McHugh "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician J. Psychiatr. Res. 12 1975 189 198
8. M. Gatz, N.L. Pedersen, S. Berg, B. Johansson, K. Johansson, J.A. Mortimer, S.F. Posner, M. Viitanen, B. Winblad, and A. Ahlbom Heritability for Alzheimer's disease: the study of dementia in Swedish twins J. Gerontol. A Biol. Sci. Med. Sci. 52 1997 117 125
9. J. Hardy Amyloid, the presenilins and Alzheimer's disease Trends Neurosci. 20 1997 154 159
10. C. Hock, K. Heese, C. Hulette, C. Rosenberg, and U. Otten Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas Arch. Neurol. 57 2000 846 851
11. R.M. Holsinger, J. Schnarr, P. Henry, V.T. Castelo, and M. Fahnestock Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease Brain Res. Mol. Brain Res. 76 2000 347 354
12. R.G.R. Ihaka A language for data analysis and graphics J. Comput. Graphical Statist. 5 1996 299 314
13. K. Itoh, K. Hashimoto, C. Kumakiri, E. Shimizu, and M. Iyo Association between brain-derived neurotrophic factor 196 G/A polymorphism and personality traits in healthy subjects Am. J. Med. Genet. 124 2004 61 63
14. M.I. Kamboh Molecular genetics of late-onset Alzheimer's disease Ann. Hum. Genet. 68 2004 381 404
15. H. Kunugi, A. Ueki, M. Otsuka, K. Isse, H. Hirasawa, N. Kato, T. Nabika, S. Kobayashi, and S. Nanko A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease Mol. Psychiatry 6 2001 83 86
16. C. Lee Irresistible force meets immovable object: SNP mapping of complex diseases Trends Genet. 18 2002 67 69
17. R. Lewontin The interaction of selection and linkage I: general considerations, heterotic models Genetics 49 1964 49 67
18. Y.J. Li, W.K. Scott, D.J. Hedges, F. Zhang, P.C. Gaskell, M.A. Nance, R.L. Watts, J.P. Hubble, W.C. Koller, R. Pahwa, M.B. Stern, B.C. Hiner, J. Jankovic, F.A. Allen Jr., C.G. Goetz, F. Mastaglia, J.M. Stajich, R.A. Gibson, L.T. Middleton, A.M. Saunders, B.L. Scott, G.W. Small, K.K. Nicodemus, A.D. Reed, D.E. Schmechel, K.A. Welsh-Bohmer, P.M. Conneally, A.D. Roses, J.R. Gilbert, J.M. Vance, J.L. Haines, and M.A. Pericak-Vance Age at onset in two common neurodegenerative diseases is genetically controlled Am. J. Hum. Genet. 70 2002 985 993
19. P.C. Maisonpierre, M.M. Le Beau, R. Espinosa III, N.Y. Ip, L. Belluscio, S.M. de la Monte, S. Squinto, M.E. Furth, and G.D. Yancopoulos Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations Genomics 10 1991 558 568
20. S. Matsushita, H. Arai, T. Matsui, T. Yuzuriha, K. Urakami, T. Masaki, S. Higuchi, Brain-derived neurotrophic factor gene polymorphisms and Alzheimer's disease, J. Neural Transm. (in press).
21. G. McKhann, D. Drachman, M. Folstein, R. Katzman, D. Price, and E.M. Stadlan Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease Neurology 34 1984 939 944
22. E.J. Mufson, J.S. Kroin, T.J. Sendera, and T. Sobreviela Distribution and retrograde transport of trophic factors in the central nervous system: functional implications for the treatment of neurodegenerative diseases Prog. Neurobiol. 57 1999 451 484
23. M.G. Murer, F. Boissiere, Q. Yan, S. Hunot, J. Villares, B. Faucheux, Y. Agid, E. Hirsch, and R. Raisman-Vozari An immunohistochemical study of the distribution of brain-derived neurotrophic factor in the adult human brain, with particular reference to Alzheimer's disease Neuroscience 88 1999 1015 1032
24. A.L. Nishimura, J.R. Oliveira, M. Mitne-Neto, C. Guindalini, R. Nitrini, V.S. Bahia, P.R. de Brito-Marques, P.A. Otto, and M. Zatz Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer's disease (LOAD) in Brazilian patients J. Mol. Neurosci. 22 2004 257 260
25. N.L. Pederson, M. Gatz, S. Berg, and B. Johansson How heritable is Alzheimer's disease late in life? Finding from Swedish twins Ann. Neurol. 55 2004 180 185
26. H.S. Phillips, J.M. Hains, M. Armanini, G.R. Laramee, S.A. Johnson, and J.W. Winslow BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer's disease Neuron 7 1991 695 702
27. M. Riemenschneider, S. Schwarz, S. Wagenpfeil, J. Diehl, U. Muller, H. Forstl, and A. Kurz A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer's disease in patients lacking the apolipoprotein E epsilon4 allele Mol. Psychiatry 7 2002 782 785
28. D.C. Rubinsztein, and D.F. Easton Apolipoprotein E genetic variation and Alzheimer's disease. A meta-analysis Dement. Geriatr. Cogn. Disord. 10 1999 199 209
29. S.J. Tsai, C.J. Hong, H.C. Liu, T.Y. Liu, L.E. Hsu, and C.H. Lin Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset Neuropsychobiology 49 2004 10 12
30. M. Ventriglia, L. Bocchio Chiavetto, L. Benussi, G. Binetti, O. Zanetti, M.A. Riva, and M. Gennarelli Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer's disease Mol. Psychiatry 7 2002 136 137
31. X. Wang, S.T. DeKosky, E. Luedecking-Zimmer, M. Ganguli, and M.I. Kamboh Genetic variation in alpha(1)-antichymotrypsin and its association with Alzheimer's disease Hum. Genet. 110 2002 356 365