Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 60, Issue 1, 2005, Pages 17-23

  Löbenberg, Raimar ^a   Kim, Jae Seung ^b   Amidon, Gordon L ^c  

^a UNIVERSITY OF ALBERTA   (Canada)

^b TSRL   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Beta blocker; Chronopharmacotherapy; Controlled release; Dog study; Immediate release; In vivo study; LC MS MS; Metoprolol; Pharmacokinetics; Pulsatile drug delivery; Pulsatile release; Sustained release

Indexed keywords

METOPROLOL; METOPROLOL TARTRATE;

ANIMAL EXPERIMENT; ARTICLE; CHRONOPHARMACOLOGY; COMPARATIVE STUDY; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CAPSULE; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG PENETRATION; DRUG SOLUBILITY; FEMALE; GASTROINTESTINAL ABSORPTION; GASTROINTESTINAL MOTILITY; GASTROINTESTINAL TRACT; IMMEDIATE RELEASE FORMULATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; PHARMACOLOGICAL PARAMETERS; PHYSIOLOGY; PULSATILE DRUG RELEASE; TABLET FORMULATION;

EID: 17444385204     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2004.11.010     Document Type: Article

References (31)

1. J. Wikstrand, B. Andersson, M.J. Kendall, H. Stanbrook, and M. Klibaner Pharmacokinetic considerations of formulation: extended-release metoprolol succinate in the treatment of heart failure J. Cardiovasc. Pharmacol. 41 2003 151 157
2. J.D. Carroll, M. Reidy, P.A. Savundra, N. Cleave, and J. McAinsh Long-acting propranolol in the prophylaxis of migraine: a comparative study of two doses Cephalalgia 10 1990 101 105
3. X.Z. Shu, K.J. Zhu, and W. Song Novel pH sensitive citrate cross-linked chitosan film for drug controlled release Int. J. Pharm. 212 2001 19 28
4. A. Rubinstein Approaches and opportunities in colon-specific drug delivery Crit. Rev. Ther. Drug Carrier Syst. 12 1995 101 149
5. E.A. Klausner, S. Eyal, E. Lavy, M. Friedman, and A. Hoffman Novel levodopa gastroretentive dosage form: in vivo evaluation in dogs J. Controlled Release 88 2003 117 126
6. P.G. Welling Infuence of food and diet on gastrointestinal drug absorption: a review J. Pharmacokinet. Biopharm. 5 1977 291 334
7. C. Crevoisier, P. Zerr, F. Calvi-Gries, and T. Nilsen Effects of food on the pharmacokinetics of levodopa in a dual-release formulation Eur. J. Pharm. Biopharm. 55 2003 71 76
8. H. Kertland Nitrate tolerance - mechanisms and prevention Conn. Med. 57 1993 232 234
9. Port-Systems. Port Capsule. US Patent: 5,387,421. USA, 1995.
10. R.E. Noble Drug therapy in the elderly Metab.-Clin. Exp. 52 2003 27 30
11. J.B. Schwartz The influence of sex on pharmacokinetics Clin. Pharmacokinet. 42 2003 107 121
12. E. Galia, E. Nicolaides, D. Horter, R. Lobenberg, C. Reppas, and J.B. Dressman Evaluation of various dissolution media for predicting in vivo performance of class I and II drugs Pharm. Res. 15 1998 698 705
13. H.M. Abdou Effect of the test parameters on dissolution rate Dissolution, Bioavailability and Bioequivalence 1989 Mack Publishing Company Easton, PA 145 171
14. N. Katori, N. Aoyagi, and T. Terao Estimation of agitation intensity in the GI tract in humans and dogs based on in vitro/in vivo correlation Pharm. Res. 12 1995 237 243
15. S.C. Chattaraj, and S.K. Das Effect of formulation variables on the preparation and in vitro-in vivo evaluation of cimetidine release from ethylcellulose micropellets Drug Dev. Ind. Pharm. 16 1990 283 293
16. N.D. Eddington, M. Ashraf, L.L. Augsburger, J.L. Leslie, M.J. Fossler, L.J. Lesko, V.P. Shah, and G.S. Rekhi Identification of formulation and manufacturing variables that influence in vitro dissolution and in vivo bioavailability of propranolol hydrochloride tablets Pharm. Dev. Technol. 3 1998 535 547
17. P. Lucker, G. Moore, I. Wieselgren, B. Olofsson, and R. Bergstrand Pharmacokinetic and pharmacodynamic comparison of metoprolol Cr Zok once daily with conventional tablets once daily and in divided doses J. Clin. Pharmacol. 30 1990 S17 S27
18. A. Goldbeter, and D. Claude Time-patterned drug administration: insights from a modeling approach Chronobiol. Int. 19 2002 157 175
19. B. Lemmer, B. Scheidel, and S. Behne Chronopharmacokinetics and chronopharmacodynamics of cardiovascular active drugs. Propranolol, organic nitrates, nifedipine Ann. NY Acad. Sci. 1991 618
20. R.J. Straka, and S.R. Benson Chronopharmacologic considerations when treating the patient with hypertension: a review J. Clin. Pharmacol. 36 1996 771 782
21. A.M. Thielemann, N. Manquez, E. Pinilla, M.N. Gai, P. Romero, A. Arancibia, and H. Chavez Chronopharmacokinetics of theophylline administered as a controlled-release tablet Int. J. Clin. Pharmaco Ther. 34 1996 130 133
22. M. Halsas, J. Hietala, P. Veski, H. Jurjenson, and M. Marvola Morning versus evening dosing of ibuprofen using conventional and time-controlled release formulations Int. J. Pharm. 189 1999 179 185
23. M. Kozak Use of chronobiology findings in therapy of cardiovascular diseases Vnitrni Lekarstvi 49 2003 308 313
24. B. Lemmer Chronopharmacological aspects for the prevention of acute coronary syndromes Eur. Heart J. 19 1998 C50 C58
25. E. Lipka, I.D. Lee, P. Langguth, H. Spahn-Langguth, E. Mutschler, and G.L. Amidon Celiprolol double-peak occurrence and gastric motility: nonlinear mixed effects modeling of bioavailability data obtained in dogs J. Pharmacokinet. Biopharm. 23 1995 267 286
26. R.L. Oberle, and G.L. Amidon The influence of variable gastric emptying and intestinal transit rates on the plasma level curve of cimetidine; an explanation for the double peak phenomenon J. Pharmacokinet. Biopharm. 15 1987 529 544
27. K. Higaki, S. Yamashita, and G.L. Amidon Time-dependent oral absorption models J. Pharmacokinet. Pharmacodyn. 28 2001 109 128
28. M. Kamba, Y. Seta, A. Kusai, and K. Nishimura Comparison of the mechanical destructive force in the small intestine of dog and human Int. J. Pharm. 237 2002 139 149
29. N. Ogawa, and S. Ohdo Chronopharmacology and DDS (drug delivery system) Nippon Rinsho 51 1993 2778 2787
30. I. Krogel, and R. Bodmeier Pulsatile drug release from an insoluble capsule body controlled by an erodible plug Pharm. Res. 15 1998 474 481
31. T. Bussemer, I. Otto, and R. Bodmeier Pulsatile drug-delivery systems Crit. Rev. Ther. Drug Carrier Syst. 18 2001 433 458