The structure and functions of transglutaminases and their role in dermatitis herpetiformis;Budowa i czynności transglutaminaz oraz ich rola w opryszczkowatym zapaleniu skóry

Dermatologia Klinicza

Volumn 7, Issue 1, 2005, Pages 37-43

  Wolnik Trzeciak, Grazyna ^a,b   Bowszyc Dmochowska, Monika ^a   Dańczak Pazdrowska, Aleksandra ^a   Dmochowski, Marian ^a  

^a Katedra i Klinika Dermatologii   (Poland)

^b AM   (Poland)

Author keywords

Dermatitis herpetiformis; Transglutaminases

Indexed keywords

ISOPEPTIDE; PROTEIN; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; UNCLASSIFIED DRUG;

AUTOIMMUNE DISEASE; DEGENERATIVE DISEASE; DERMATITIS HERPETIFORMIS; ENZYME ANALYSIS; ENZYME STRUCTURE; FUNCTIONAL ASSESSMENT; HUMAN; PATHOPHYSIOLOGY; PEPTIDE ANALYSIS; PROTEIN FAMILY; REVIEW; STRUCTURE ACTIVITY RELATION;

EID: 17444369431     PISSN: 17307201     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (79)

1. Griffin M., Casadio R., Bergamini C.M.: Transglutaminases: Nature's biological glues. Biochem. J., 2002, 368, 377-396.
2. Chen J.S.K., Metha K.: Tissue transglutaminase: an enzyme with a split personality. Int. J. Biochem. Cell. Biol., 1999, 31, 817-836.
3. Greenberg C.S., Birckbichler P.J., Rice R.H.: Transglutaminases: multifunctional cross-linking enzymes that stabilize tissues. FASEB J., 1991, 15, 3071-3077.
4. Ciccocioppo R., Di Sabatino A., Ara C., Biagi F., Perilli M., Amicosante G., Cifone M.G., Corazza G.R.: Gliadin and tissue transglutaminase complexes in normal and coeliac duodenal mucosa. Clin. Exp. Immunol., 2003, 134, 516-524.
5. Bergamini C.M.: GTP modulates calcium binding and cation-induced conformational changes in erythrocyte transglutaminase. FEBS Lett., 1988, 239, 255-258.
6. 2+ and nucleotides. Biochem. J., 1996, 313, 803-808.
7. Narasimhan C., Lai C.S., Joseph J.: Syntheses and transglutaminase- catalysed incorporation of novel spin-labeled primary amines into proteins. Bioorganic Chemistry, 1996, 24, 50-58.
8. Aeschlimann D., Koeller M.K., Allen-Hoffmann B.L., Mosher D.F.: Isolation of cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription-polymerase reaction with degenerate primers. J. Biol. Chem., 1998, 273, 3452-3460.
9. Kim I.G., Jeffrey J., Gorman J., Park S.C., Chung S.I., Steinert P.M.: The deduced sequence of the Novel Protransglutaminase E (Tgase3) of Human and Mouse. J. Biol. Chem., 1993, 268, 12682-12690.
10. Piacentini M., Collizi V.: Tissue transglutaminase: apoptosis versus autoimmunity. Immunol. Today, 1999, 20, 130-134.
11. De Laurenzi V., Melino G.: Gene Disruption of Tissue Transglutaminase. Mol. Cell. Biol., 2001, 1, 148-155.
12. Kim H.C., Nemes Z., Idler W.W., Hyde C.C., Stenert P.M., Ahvazi B.: Crystallization and preliminary X-ray analysis of human transglutaminase 3 from zymogen to active form. J. Struct. Biol., 2001, 135, 73-77.
13. Hitomi K., Ikeda N., Maski M.: Immunological detection of proteolytically activated epidermal-type transglutaminase (Tgase3) using cleavage-site specific antibody. Biosci. Biotechnol. Biochem., 2003, 67, 2492-2494.
14. Takahashi M., Tezuka T., Katunuma N.: Phosphorylated cystatin alpha is a natural substrate of epidermal transglutaminase for formation of skin cornified envelope. FEBS Lett., 1992, 308, 79-82.
15. Takahashi M., Tezuka T., Kakegawa H., Katunuma N.: Linkage between phosphorylated cystatin alpha and filaggrin by epidermal transglutaminase as a model of cornified and inhibition of catepsin L activity by cornified envelope and the conjugated cystatin alpha. FEBS Lett., 1994, 340, 173-176.
16. Michel S. Demarchez M.: Localization and in vivo activity of epidermal transglutaminase. J. Invest. Dermatol., 1988, 90, 472-474.
17. Hitomi K., Presland R., Nakayama T, Fleckman P., Dale B. A., Maki M.: Analysis of epridermal-type transglutaminase (transglutaminase 3) in human stratified epithelia and cultured keratinocytes using monoclonal antibodies. J. Derm. Science, 2003, 32, 95-103.
18. Kim S.Y., Grant P., Lee J.H., Pant H.C., Steinert P.M.: Differential expression of multiple transglutaminases in human brain. Increased expression and cross-linking by transglutaminases 1 and 2 in Alzheimer's disease. J. Biol. Chem., 1999, 274, 30715-30721.
19. Sárdy M., Kárpáti S., Merkl B., Paulsson M., Smyth N.: Epidermal transglutaminase (Tgase 3) is the autoantigen of dermatitis herpetiformis. J. Exp. Med., 2002, 195, 747-757.
20. Hitomi K., Horio Y., Ikura K., Yamanishi K., Maki M.: Analysis of epidermal-type transglutaminase (Tgase 3) expression in mouse tissues and cell lines. Int. J. Biochem. Cell. Biol., 2001, 33, 491-498.
21. Van Hooijdonk C.A., Steijlen P.M., Bergers M., Mier P.D., Traupe H., Happle R.: Epidermal transglutaminase in the ichthyoses. Acta Derm. Venereol., 1991, 71, 173-175.
22. Dubbink H.J., Hoedemaeker R.F., van der Kwast T.H., Schroder F.H., Romijn J.C.: Human prostate-specific transglutaminase: a newprostatic marker with a unique distribution pattern. Lab. Invest., 1999, 79, 141-150.
23. Candi E., Oddi S., Paradisi A., Terrinoni A., Rnalli M., Tcofoli P., Citro G., Scarpato S., Puddu P., Mellino G.: Expression of transglutaminase 5 in normal and pathologic human epidermis. J. Invest. Dermatol., 2002, 119, 670-677.
24. Rufini A., Vilbois F., Paradisi A., Oddi S., Tartaglione R., Leta A., Bagetta G., Guerrieri P., Finazzi-Agro A., Melino G., Cndi E.: Transglutaminase 5 is acetylated at the N-terminal end. Amino Acids, 2004, 26, 425-430.
25. Grenard P., Bates M.K., Aeschlimann D.: Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase 2. J. Biol. Chem., 2001, 276, 33066-33078.
26. Sblattero D., Florian F., Azzoni E., Zyla T., Park M., Baldas V., Not T., Ventura A., Bradbury A., Marzari R.: The analysis of the fine specificity of celiac disease antibodies using tissue transglutaminase fragments. Eur. J. Biochem., 2002, 269, 5175-5181.
27. Iismaa S.E., Chung M.J., Wu M.J., Teller D.C., Yee V.C., Graham R.M.: The core domain of the tissue transglutaminase Gh hydrolyses GTP and ATP. Biochemistry, 1997, 36, 11654-11655.
28. Beninati S., Piacentini M.: The transglutaminase family: an overview: Minireview article. Amino Acids, 2004, 26, 367-372.
29. Ahvazi B., Kim H.C., Kee S.H., Names Z., Steinert P.M.: Three-dimensional structure of the human transglutaminase 3 enzyme: binding of calcium ions changes structure for activation. EMBO J., 2002, 21, 2055-2067
30. Kim I.G., Lee S.C., Lee J.H., Yang J.M., Chung S.I., Stenert P.M.: Structure and organization of the human transglutaminase 3 gene: evolutionary relationship to the transglutaminase family. J. Invest. Dermatol., 1994, 103, 137-142.
31. Kárpáti S.: Dermatitis herpetiformis: close to unravelling a disease. J. Derm. Sci., 2004, 34, 83-90.
32. Grenard P., Bresson-Handi S., Alaonis E.L., Chevallier M., Vitton D.A., Ricard-Blum S.: Transglutaminase-mediated cross-linking is involved in the stabilization of extracellular matrix in human liverfibrosis. J. Hepatol., 2001, 35, 367-375.
33. Johnson T.S., Skill N.J., El Nahas A.M., Oldroyd S.D., Thomas G.L., Douthwaite J.A., Haylor J.L., Griffin M.: Transglutaminase transcription and antigen translocation in experimental renal scarring. J. Am. Soc. Nephrol., 1999, 10, 2146-2157.
34. Richards P., Masek L., Brown R.F.: Biochemical and cellular mechanism of pulmonary fibrosis.Toxicol. Pathol., 1991, 19, 526-539.
35. Arentz-Hansen H., Korner R., Molberg O., Quarsten H., Vader W., Kooy Y.M., Lundin K.E., Honing F, Roepstorff P., Sollid L.M., McAdam S.N.: The intestinal T cell response to alpha gliadin in adult celiac disease is focused on a single deamidated glutaminae targeted by tissue transglutaminase. J. Exp. Med., 2000, 191, 603-612.
36. Villalta D., Bizzaro N., Tonutti E., Tozolli R.: IgA anti- transglutaminase autoantibodies in systemic lupus erythematosus and Sjögren syndrome. Clin. Chem 2002, 48, 1133.
37. Luft L., Barr S.G., Martin L.O., Chan E.K.L., Fritzler M.J.: Autoantibosies to tissue transglutaminase in Sjögren's syndrome and related rheumatic diseases. J. Rheumatol., 2003, 30, 2609-2613.
38. Amendola A., Rodolfo C., Di Caro A., Ciccosanti F., Falasca L., Piacentini M.: "Tissue" transglutaminase expression in HIV-infected cells: an enzyme with an antiviral effect? Ann. NY Acad. Sci., 2001, 946, 108-120.
39. Rosenthal A.K., Gohr C., Henry L.A., Le M.: Participation of transglutaminase in the activation in the activation of latent Transforming Growth Factor β1 in aging articular cartilage. Arthritis. Rheum., 2000, 43, 1729-1733.
40. Johnson K., Hashimoto S., Lotz M., Pritzker K., Terkeltaub R.: Interleukin-1 induce pro-mineralizing activity of cartilage tissue transglutaminase and factor XIIIa. Am. J. Pathol., 2001, 159, 149-163.
41. Johnson G.V., Cox T.M., Lockhart J.P., Zinnerman M.D., Miller M.L., Powers R.E: Transglutaminase activity is increased in Alzheimer's disease brain. Brian. Res., 1997, 751, 323-329.
42. Rasmussen L.K., Sorensen E.S., Petersen T.E., Gliemann J., Jensen PH.: Identification of glutamine and lysine residues in Alzheimer amyloid βA4 peptide responsible for transglutaminase in situ: possible functional and metabolic effects of polyamination. J. Neurochem., 1999, 73, 1871-1880.
43. Caccamo D., Campisi A., Curro M., Li Volti G., Lentile R.: Exocitotoxic and post-ischemic neurodegeneration: Involvement of transglutaminases. Amino Acid: 2004, 27, 373-379.
44. Pepe I., Occhino E., Cella G., Luongo A., Guardascione F., Gentile V.: Biochemical mechanisms for a possible involvement of the transglutaminase activity in the pathogenesis of the polyglutamine diseases: Minireview article. Amino Acids, 2004, 26, 431-434.
45. Hand D., Elliott B., Griffin M.: Expression of the cytosolic and particulate forms of transglutamniase during chemically induced rat liver carcinogenesis. Biochim. Biophys. Acta, 1988, 970, 137-145.
46. Birckbichler P.J., Bonnerm R.B., Hurst R.E., Bane B.L., Pitha J.V., Hemstreet G.P. 3rd: Loss of tissue transglutamiase as biomarker for prostate adenocarcinoma. Cancer, 2000, 89, 412-423.
47. Michel S., Reichert U., Isnard J.L., Shroot B., Schmidt R.: Retinoic acid controls expression of epridermal transglutaminase at the pretranslational level. FEBS Lett., 1989 ,258, 35-38.
48. Rosenthal D.S., Griffiths C.E., Yuspa S.H., Roop D.R., Voorhees J.J.: Acute or chronic topical retinoic acid treatment of human skin in vivo alters the expression of epidermal transglutaminase, loricrin, involucrin, filaggrin, and keratins 6 and 13. but not keratins 1, 10, and 14. J. Invest. Dermatol., 1992, 99, 145.
49. Griffiths C.E., Rosenthal D.S., Reddy A.P., Elder J.T., Astrom A., Leach K., Wang T.S., Finkel L.J., Yuspa S.H., Voorhees J.J.: Short-term retinoic acid treatment increase: in vivo, but decreases in vitro, epidermal transglutaminase-K enzyme activity and immunoreactivity. J. Invest. Dermatol., 1992, 99, 283-288.
50. Skovbjerg H., Noren O., Athonsen D., Moller J., Sjöström H.: Gliadin is a good substrate of several transglutaminases: possible implication in the pathogenesis of coeliac disease. Scand. J. Gastroenterol., 2002, 37, 812-817.
51. Dmochowski M.: Autoimmunizacyjne dermatozy pȩcherzowe. www.dmochowski.com.pl
52. Katz S., Falchuk M., Dahl M.V., Rogetine G.N., Strober W.: HLA-B: A genetic link between dermatitis herpetiformis and gluten-sensitive enteropathy. J. Clin. Invest., 1972, 51, 2977-2980.
53. Jabłońska S., Chorzelski T.: Choroby skóry. PZWL, Warszawa, 1997, 232-266.
54. Oxentenko A.S., Murray J.A.: Celiac disease and dermatitis herpetiformis: the spectrum of gluten-sensitive enteropathy. Int. J. Derm., 2003, 42, 585-587
55. Spurkland A., Ingvarsson G., Falk E.S., Knutsen I., Sollid L.M., Thorsby E.: Dermatitis herpetiformis and celiac disease are both primarily associated with HLA-DQ (alpha*0501, beta1*02) or the HLA-DQ (alpha 1*03, beta 1*0302) heterodimers. Tissue Antigens, 1997, 49, 29-34.
56. Nicolas M.E.O., Krause P.K., Gibson L.E., Murray J.A.: Dermatitis herpetiformis. Int. J. Derm., 2003, 42, 588-600.
57. Gebhard R.L., Falchuk S., Katz S.I, Sessoms C., Rogentine G.N., Strober W.: Dermatitis herpetiformis. Immunologic concomitans of small intestine disease and relationship to histocompatibility antigen HL-A8. J. Clin. Invest., 1974, 54, 98-103
58. Sams H.H.: Dermatitis herpetiformis. www.emedicine.com
59. Kosnai I., Kárpáti S., Torok E., Bucsky P., Gyodi E.: Dermatitis herpetiformis in monozygous twins: discordance for dermatitis herpetiformis and concordance for gluten-sensitive enteropathy. Eur. J. Pediatr., 1985, 144, 404-405.
60. Anstey A., Wilkinson J.D., Walshe M.M.: Dermatitis herpetiformis in monozygous twins- concordance dermatitis herpetiformis and gluten sensitive enteropathy . Clin. Exp. Dermatol., 1991, 16, 51-52.
61. Harvonen K., Karrell K., Halopainen P., Collin P., Partanen J., Reunala T.: Concordance of dermatitis herpetiformis and celiac disease in monozygous twins. J. Invest. Dermatol., 2000, 115, 990-993.
62. Kárpáti S., Kósnai I., Török E., Kovács J.B.: Immunoglobulin A deposition in jejunal mucosa of children with dermatitis herpetiformis. J. Invest. Dermatol., 1988, 91, 336-339.
63. Sárdy M., Odenthal U., Kárpáti S., Paulsson M., Smyth N.: Recombinant human tissue transglutaminase for the diagnosis of gluten-sensitive enteropathy. Clin. Chem., 1999, 45, 2142-2149.
64. Wankiewicz A., Dymek G., Placek W., Odrowa̧ż-Sypniewska G.: Autoprzeciwciała w zapaleniu opryszczkowatym skóry. Przegl. Dermatol., 2004, 91, 133-138.
65. Braun Falco O., Plewig G., Wolff H., Burgdorf W.H.: Dermatologia. Czelej, Lublin, 2002, 615-657.
66. Egelrud T., Back O.: Dermatitis herpetiformis: Biochemical properties of the granular deposits of IgA in papillary dermis. Characterisation of SDS-soluble IgA-like material and potentially antigen-binding IgA fragments relesed by pepsin. J. Invest. Dermatol., 1985, 84, 239-245.
67. Chorzelski T.P., Beutner E.H., Sulej J. Tchórzewska H., Jabłońska S., Kumar V., Kapuścińska A.: IgA anti-endomysium antibody. A ew immunological marker of dermatitis herpetiformis and celiac disease. Br J. Dermatol., 1984, 111, 395-402.
68. Dieterich W., Laag E., Bruckner-Tuderman L., Reunala T., Kárpáti S., Zágoni T., Riecken O., Schuppan D.: Antitibodies to tissue transglutaminase as serologic markers in patients with dermatitis herpetiformis. J. Invest. Dermatol., 1999, 113, 133-136.
69. Korponay-Szabó I.R., Halttunen T., Szalai Z., Laurilla K., Király R., Kovács J.B., Fésüs L., Mäki M.: In vivo targeting of intestinal and extraintestinal transglutaminase 2 by celiac autoantibodies. Gut, 2004, 53, 641-648.
70. Korponay-Szabó I.R., Laurila K., Szondy Z., Halttunen T., Szalai Z., Dahlbom I., Rantala I., Kovács J.B., Fésüs L., Maki M.: Missing endomysial and reticulin binding of celiac antibodies in transglutaminase 2 knockout tissues. Gut, 2003, 52, 199-204.
71. Sárdy M., Kárpáti S., Peterfy F., Rasky K., Tomsits E., Zagoni T., Horvath A.: Comparison of tissue transglutaminase ELISA with the endomysium antibody test in the diagnosis of gluten-sensitive enteropathy. Z. Gastroenterol., 2000, 38, 357-364.
72. Caproni M., Cardinali C., Renzi D., Calabro A., Fabbri P.: Tissue transglutaminase antibody assesment in dermatitis herpetiformis. Br. J. Dermatol., 2001, 144, 196.
73. Biagi F., Bassi E., Ardigo M., Vignini M.A., Carvaggi M., Borroni G., Corazza G.R.: In patients with dermatitis herpetiformis distribution of transglutaminase in cutaneous tissue does not differ from controls. Dig. Liver Dis., 2003, 35, 41-45.
74. Ghahestani A.S., Nikbakht N., Fry L., Reunala T., Uitto J., Ghohestani R.: Circulating IgA autoantibodies to epidermal transglutaminase 3 can not distinguish dermatitis herpetiformis from celiac disease. J. Invest. Dermatol., 2004, 122, A14 (Abstract).
75. Wolnik-Trzeciak G., Dańczak-Pazdrowska A., Bowszyc-Dmochowska M., Dmochowski M.: Typy skórnych złogów IgA i IgA1, przeciwciała IgA, IgA1, IgA2 przeciwko środmiesnej i przeciwciała IgA przeciwko tkankowej transglutaminazie w opryszczkowatym zapaleniu skóry. Przegl. Dermatol., 2004, 84.
76. Karpati S., Meurer M., Stolz W., Schrallhammer K., Krieg T., Braun-Falco O.: Dermatitis herpetiformis bodies. Ultrastructural study on the skin of patients using direct preembedding immunogold labeling. Arch. Dermatol., 1990, 126, 1469-1474.
77. Helin H., Mustonen J., Reunala T., Pasternack A.: IgA nephropathy associated with celiac disease and dermatitis hrpetiformis. Arch. Pathol. Lab. Med., 1983, 107, 324-327.
78. Lawley T.J., Hall R.P., Fauci A.S., Katz S.I., Hamburger M.I., Frank M.M.: Defective Fc-receptor functions associated with the HLA-B8/DRw3 haplotype: studies in patients with dermatitis herpetiformis and normal subjects. N. Engl. J. Med., 1981, 304, 185-192.
79. Smith A.D., Streilein R.D., Hall R.P.: Neutrophil CD11b, L-selectin and FcIgA receptors in patients with dermatitis herpetiformis. Br. J. Dermatol., 2002, 147, 1109-1117.