Conversion of human α-lactalbumin to an apo-like state in the complexes with basic poly-amino acids: Toward understanding of the molecular mechanism of antitumor action of HAMLET

Journal of Proteome Research

Volumn 4, Issue 2, 2005, Pages 564-569

  Permyakov, Serge E ^a   Pershikova, Irina V ^a   Zhadan, Andrei P ^a   Goers, John ^b   Bakunts, Anush G ^a   Uversky, Vladimir N ^a,c,e   Berliner, Lawrence J ^d   Permyakov, Eugene A ^a  

^a INSTITUTE FOR BIOLOGICAL INSTRUMENTATION   (Russian Federation)

^b CALIFORNIA POLYTECHNIC STATE UNIVERSITY   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF DENVER   (United States)

^e INDIANA UNIVERSITY   (United States)

Author keywords

lactalbumin; Calcium binding; Electrostatics; Histones; Poly amino acids; Thermal stability

Indexed keywords

ALPHA LACTALBUMIN; AMINO ACID DERIVATIVE; APOLIPOPROTEIN; CALCIUM ION; OLEIC ACID; POLYAMINOACID; POLYARGININE; POLYLYSINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING AFFINITY; CALCIUM BINDING; CIRCULAR DICHROISM; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; DIFFERENTIAL SCANNING CALORIMETRY; ELECTRICITY; FLUORESCENCE ANALYSIS; IONIC STRENGTH; MELTING POINT; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEOMICS; STEADY STATE; STRUCTURE ANALYSIS;

AMINO ACIDS; ANTINEOPLASTIC AGENTS; CALORIMETRY; CIRCULAR DICHROISM; HUMANS; LACTALBUMIN; OLEIC ACID; SPECTROMETRY, FLUORESCENCE; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 17444365482     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr0497778     Document Type: Article

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