Effect of lycopene supplementation on lung function after exercise in young athletes who complain of exercise-induced bronchoconstriction symptoms

Annals of Allergy, Asthma and Immunology

Volumn 94, Issue 4, 2005, Pages 480-485

  Falk, Bareket ^a,b   Gorev, Ruti ^c   Zigel, Levana ^a   Ben Amotz, Ami ^d   Neuman, Ittai ^e  

^a WINGATE INSTITUTE   (Israel)

^b BROCK UNIVERSITY   (Canada)

^c Ichilov Medical Center   (Israel)

^d NATIONAL INSTITUTE OF OCEANOGRAPHY   (Israel)

^e Institute of Medical Genetics   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; LYC O MATO; LYCOPENE; PLACEBO;

ADOLESCENT; ADULT; ARTICLE; ATHLETE; BREATHING DISORDER; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; DYNAMIC EXERCISE; EXERCISE TEST; FEMALE; FORCED EXPIRATORY VOLUME; HEART RATE; HUMAN; LUNG FUNCTION; LUNG FUNCTION TEST; MALE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT INFLAMMATION; SCHOOL CHILD; SUPPLEMENTATION; TREADMILL EXERCISE;

EID: 17444365035     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)61119-2     Document Type: Article

References (34)

1. Hebestreit H. Exercise and physical activity in the child with asthma. In: Armstrong N, van Mechelen W, eds. Paediatric Exercise Science and Medicine. Oxford, England: Oxford University Press; 2000:323-330.
2. Rupp N. Diagnosis and management of exercise-induced asthma. Physician Sportsmed. 1996;24:77-87.
3. Weiler JM, Layton T, Hunt M. Asthma in United States Olympic athletes who participated in the 1996 Summer Games. J Allergy Clin Immunol. 1998;102:722-726.
4. Weiler JM, Ryan EJ. Asthma in United States Olympic athletes who participated in the 1998 Olympic Winter Games. J Allergy Clin Immunol. 2000;106:267-271.
5. Wilber RL, Rundell KW, Szmedra L, et al. Incidence of exercise-induced bronchospasm in Olympic winter sport athletes. Med Sci Sports Exerc. 2000;32:732-737.
6. Anderson SD, Fitch K, Perry CP, et al. Responses to bronchial challenge submitted for approval to use inhaled β2-agonists before an event at the 2002 Winter Olympics. J Allergy Clin Immunol. 2003;111:45-50.
7. Hatch GF. Asthma, inhaled oxidants, and dietary antioxidants. Am J Clin Nutr 1995;61(suppl 3):6255-6305.
8. Rahman I, Morrison D, Donalson K, MacNee W. Systemic oxidative stress in asthma, COPD and smokers. Am J Respir Crit Care Med. 1996;154(pt 1):1055-1060.
9. Smith LJ, Shamsuddin M, Sporn PH, et al. Reduced superoxide dismutase in lung cells of patients with asthma. Free Radic Biol Med. 1997;22:1301-1307.
10. Singh VN. A current perspective on nutrition and exercise. J Nutr. 1992;122(suppl 3):760-765.
11. Barnes PJ. Reactive oxygen species and airway inflammation. Free Radic Biol Med. 1990;9:235-243.
12. Calhoun WJ, Bush RK. Enhanced reactive oxygen species metabolism of airspace cells and airway inflammation follow antigen challenge in human asthma. J Allergy Clin Immunol. 1990;86:306-313.
13. Smith LJ, Houston M, Anderson J. Increased levels of glutathione in bronchoalveolar lavage fluid from patients with asthma. Am Rev Respir Dis. 1993;147(pt 1):1461-1464.
14. Doelman CJ, Bast A. Oxygen radicals in lung pathology. Free Radic Biol Med. 1990;9:381-400.
15. Vachier I, Le Doucen C, Loubatiere J, et al. Imaging reactive oxygen species in asthma. J Biolumin Chemilumin. 1994;9: 171-175.
16. Cohen HA, Neuman I, Nahum H. Blocking effect of vitamin C in exercise-induced asthma. Arch Pediatr Adolesc Med. 1997; 151:367-370.
17. Neuman I, Nahum H, Ben-Amotz A. Prevention of exercise-induced asthma by a natural isomer mixture of β-carotene. Ann Allergy Asthma Immunol. 1999;82:549-553.
18. Neuman I, Nahum H, Ben-Amotz A. Reduction of exercise-induced asthma oxidative stress by lycopene, a natural antioxidant. Allergy. 2000;55:1184-1189.
19. Ahmad S, Pardini RS. Mechanisms for regulating oxygen toxicity in phytophagous insects. Free Radic Biol Med. 1990;8:401-413.
20. Witt EH, Reznick AZ, Viguie CA, Starke-Reed P, Packer L. Exercise, oxidative damage and effects of antioxidant manipulation. J Nutr. 1992;122(suppl):766-773.
21. Kanter MM, Nolte LA, Holloszy JO. Effects of an antioxidant vitamin mixture on lipid peroxidation at rest and post-exercise. J Appl Physiol. 1992;74:965-969.
22. Michelborough T, Getshell R. Dietary components with demonstrated effectiveness in decreasing the severity of exercise-induced asthma. Sports Med. 2003;33:671-681.
23. Rao AV, Agarwal S. Role of antioxidant lycopene in cancer and heart disease. J Am Coll Nutr. 2000;19:563-569.
24. Anderson SD. EIA: new thinking and current management. J Respir Dis. 1986;7:48-61.
25. Rundell KW, Wilber RL, Szmedra L, et al. Exercise-induced asthma screening of elite athletes: field versus laboratory exercise challenge. Med Sci Sports Exerc. 2000;32:309-316.
26. Slaughter MH, Lohman TG, Boileau BA, et al. Skinfold equations for estimation of body fatness in children. Youth Hum Biol. 1988;709-713.
27. Borg GAV. Physical Performance and Perceived Exertion: Studia Psychologica et Paedagogica, Series Altera, Investigationes XI. Lund, Sweden: Gleerup; 1962.
28. Baurnefeind JC. Carotenoids as Colorants and Vitamin A Precursors. New York, NY: Academic Press; 1981:938.
29. Beck KC, Joyner MJ, Scanlon PD. Exercise-induced asthma: diagnosis, treatment, and regulatory issues. Exerc Sports Sci Rev. 2002;30:1-3.
30. Carlsen KH, Engh G, Mork M. Exercise-induced bronchoconstriction depends on exercise load. Respir Med. 2000;94: 750-755.
31. Bar-Or O. Pediatric Sports Medicine for the Practitioner. New York, NY: Springer-Verlag; 1983.
32. Ennis M, Shields MD. Childhood asthma: an inflammatory disease? J Physiol Pharmacol. 1997;48(suppl 2):43-49.
33. Holzer K, Anderson SD, Douglass J. Exercise in elite summer athletes: challenges for diagnosis. J Allergy Clin Immunol. 2002;110:374-380.
34. Tanner JM. Growth at Adolescence. 2nd ed. Oxford, England: Blackwell Scientific Publications; 1962.