Interferon-γ inhibits in vitro mobilization of eosinophils by interleukin-5

International Archives of Allergy and Immunology

Volumn 136, Issue 3, 2005, Pages 295-302

  Park, Choon Sik ^a   Eun, Nam Choi ^b   Jung, Sun Kim ^b   Yun, Sung Choi ^a   Tai, Youn Rhim ^a   Hun, Soo Chang ^b   Il, Yup Chung ^b  

^a Soonchunhyang University College of Medicine   (South Korea)

^b Hanyang University   (South Korea)

Author keywords

Asthma; Eosinophils; Interferon ; Interleukin 5; Interleukin 6; Tumor necrosis factor

Indexed keywords

CYCLOHEXIMIDE; GAMMA INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT CYTOKINE; RECOMBINANT INTERLEUKIN 10; RECOMBINANT INTERLEUKIN 13; RECOMBINANT INTERLEUKIN 1BETA; RECOMBINANT INTERLEUKIN 4; RECOMBINANT INTERLEUKIN 5; RECOMBINANT INTERLEUKIN 6; RECOMBINANT TUMOR NECROSIS FACTOR; CYTOKINE;

ALLERGIC DISEASE; ARTICLE; CHEMOTAXIS; CONTROLLED STUDY; DRUG EFFECT; EFFECTOR CELL; ENZYME PHOSPHORYLATION; EOSINOPHIL; HUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RESPIRATORY TRACT ALLERGY; STATISTICAL SIGNIFICANCE; CELL SHAPE; IMMUNOLOGY; IN VITRO STUDY; INFLAMMATION; METABOLISM; NEUTROPHIL CHEMOTAXIS; PATHOLOGY; PHOSPHORYLATION; TH1 CELL; TH2 CELL;

CELL SHAPE; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; EOSINOPHILS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; INFLAMMATION; PHOSPHORYLATION; TH1 CELLS; TH2 CELLS;

EID: 17244376776     PISSN: 10182438     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083957     Document Type: Article

References (37)

1. Hogan SP, Matthaei KI, Young JM, Koskinen A, Young IG, Foster PS: A novel T cell-regulated mechanism modulating allergen-induced airways hyperreactivity in BALB/c mice independently of IL-4 and IL-5. J Immunol 1998;61:1501-1509.
2. Gleich GJ: Mechanisms of eosinophil-associated inflammation. J Allergy Clin Immunol 2000;105:651-663.
3. Riffo-Vasquez Y, Spina D: Role of cytokines and chemokines in bronchial hyperresponsiveness and airway inflammation. Pharmacol Ther 2002;94:185-211.
4. Gavett SH, O'Hearn DJ, Li X, Huang SK, Finkelman FD, Wills-Karp M: Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice. J Exp Med 1995;182:1527-1536.
5. Barnes PJ: Endogenous inhibitory mechanisms in asthma. Am J Respir Crit Care Med 2000;16:S176-S181.
6. Baatjes AJ, Sehmi R, Saito H, Cyr MM, Dorman SC, Inman MD, O'Byrne PM, Denburg JA: Anti-allergic therapies: effects on eosinophil progenitors. Pharmacol Ther 2002;95:63-72.
7. Hofstra CL, Van Ark I, Hofman G, Kool M, Nijkamp FP, Van Oosterhout AJ: Prevention of Th2-like cell responses by coadministration of IL-12 and IL-18 is associated with inhibition of antigen-induced airway hyperresponsiveness, eosinophilia, and serum IgE levels. J Immunol 1998;161:5054-5060.
8. Fernandez-Botran R, Sanders VM, Mosmann TR, Vitetta ES: Lymphokine-mediated regulation of the proliferative response of clones of T helper 1 and T helper 2 cells. J Exp Med 1998;168:543-558.
9. Mosmann TR, Coffman RL: TH1 and TH2 cells different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989;7:145-173.
10. Yoshida M, Leigh R, Matsumoto K, Wattie J, Ellis R, O'Byrne PM, Inman MD: Effect of interferon-gamma on allergic airway responses in interferon-gamma- deficient mice. Am J Respir Crit Care Med 2002;166:451-456.
11. Coyle AJ, Tsuyuki S, Bertrand C, Huang S, Aguet M, Alkan SS, Anderson GP: Mice lacking the IFN-gamma receptor have impaired ability to resolve a lung eosinophilic inflammatory response associated with a prolonged capacity of T cells to exhibit a Th2 cytokine profile. J Immunol 1996;156:2680-2685.
12. Hofstra CL, Van Ark I, Hofman G, Nijkamp FP, Jardieu PM, Van Oosterhout AJ: Differential effects of endogenous and exogenous interferon-gamma on immunoglobulin E, cellular infiltration, and airway responsiveness in a murine model of allergic asthma. Am J Respir Cell Mol Biol 1998;19:826-835.
13. Ochiai K, Kagami M, Matsumura R, Tomioka H: IL-5 but not interferon-gamma (IFN-gamma) inhibits eosinophil apoptosis by up-regulation of bcl-2 expression. Clin Exp Immunol 1997;107:198-204.
14. Choi EN, Choi MK, Park CS, Chung IY: A parallel signal-transduction pathway for eotaxin-and interleukin-5-induced eosinophil shape change. Immunology 2003;108:245-256.
15. Sabroe I, Hartnell A, Jopling LA, Bel S, Ponath PD, Pease JE, Collins PD, Williams TJ: Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. J Immunol 1999;162:2946-2955.
16. 4 biosynthesis. J Biol Chem 2000;275:10968-10975.
17. Schweizer RC, van Kessel-Welmers BA, Warringa RA, Maikoe T, Raaijmakers JA, Lammers JW, Koenderman L: Mechanisms involved in eosinophil migration. Platelet-activating factor-induced chemotaxis and interleukin-5-induced chemokinesis are mediated by different signals. J Leukoc Biol 1996;59:347-756.
18. Moser R, Fehr J, Bruijnzeel PL: IL-4 controls the selective endothelium-driven transmigration of eosinophils from allergic individuals. J Immunol 1992;149:1432-1438.
19. Pope SM, Brandt EB, Mishra A, Hogan SP, Zimmermann N, Matthaei KI, Foster PS, Rothenberg ME: IL-13 induces eosinophil recruitment into the lung by an IL-5- and eotaxin-dependent mechanism. J Allergy Clin Immunol 2001;108:594-601.
20. Horie S, Okubo Y, Hossain M, Sato E, Nomura H, Koyama S, Suzuki J, Isobe M, Sekiguchi M: Interleukin-13 but not interleukin-4 prolongs eosinophil survival and induces eosinophil chemotaxis. Intern Med 1997;36:179-185.
21. Temkin V, Levi-Schaffer F: Mechanism of tumour necrosis factor alpha mediated eosinophil survival. Cytokine 2001;15:20-26.
22. Han SJ, Kim JH, Noh YJ, Chang HS, Kim CS, Kim KS, Ki SY, Park CS, Chung IY: Interleukin (IL)-5 downregulates tumor necrosis factor (TNF)-induced eotaxin messenger RNA (mRNA) expression in eosinophils. Induction of eotaxin mRNA by TNF and IL-5 in eosinophils. Am J Respir Cell Mol Biol 1999;21:303-310.
23. Broide DH, Stachnick G, Castaneda D, Nayar J, Sriramarao P: Inhibition of eosinophilic inflammation in allergen-challenged TNF receptor p55/p75- and TNF receptor p55-deficient mice. Am J Respir Cell Mol Biol 2001;24:304-311.
24. Broide DH, Lotz M, Cuomo AJ, Coburn DA, Federman EC, Wasserman SI: Cytokines in symptomatic asthma airways. J Allergy Clin Immunol 1992;89:958-967.
25. Anguita J, Rincon M, Samanta S, Barthold SW, Flavell RA, Fikrig E: Borrelia burgdorferi-infected, interleukin-6-deficient mice have decreased Th2 responses and increased Lyme arthritis. J Infect Dis 1998;178:1512-1515.
26. Rincon M, Anguita J, Nakamura T, Fikrig E, Flavell RA: Interleukin (IL)-6 directs the differentiation of IL-4-producing CD4+ T cells. J Exp Med 1997;185:461-469.
27. Virchow JC Jr, Kroegel C, Walker C, Matthys H: Inflammatory determinants of asthma severity: Mediator and cellular changes in bronchoalveolar lavage fluid of patients with severe asthma. J Allergy Clin Immunol 1996;98:S27-S33.
28. Boguniewicz M, Martin RJ, Martin D, Gibson U, Celniker A, Williams M, Leung DY: The effects of nebulized recombinant interferon-gamma in asthmatic airways. J Allergy Clin Immunol 1995;95:133-135.
29. Li XM, Chopra RK, Chou TY, Schofield BH, Wills-Karp M, Huang SK: Mucosal IFN-gamma gene transfer inhibits pulmonary allergic responses in mice. J Immunol 1996;157:3216-3219.
30. Maggi E, Parronchi P, Manetti R, Simonelli C, Piccinni MP, Rugiu FS, De Carli M, Ricci M, Romagnani S: Reciprocal regulatory effects of IFN-gamma and IL-4 on the in vitro development of human Th1 and Th2 clones. J Immunol 1992;148:2142-2147.
31. Bruselle GG, Kips JC, Peleman RA, Joos GF, Devos RR, Tavernier JH, Pauwels RA: Role of IFN-gamma in the inhibition of the allergic airway inflammation caused by IL-12. Am J Respir Cell Mol Biol 1997;17:767-771.
32. Rais M, Wild JS, Choudhury BK, Alam R, Stafford S, Dharajiya N, Sur S: Interleukin-12 inhibits eosinophil differentiation from bone marrow stem cells in an interferon-gamma-dependent manner in a mouse model of asthma. Clin Exp Allergy 2002;32:627-632.
33. Iwamoto I, Nakajima H, Endo H, Yoshida S: Interferon gamma regulates antigen-induced eosinophil recruitment into the mouse airways by inhibiting the infiltration of CD4+ T cells. J Exp Med 1993;177:573-576.
34. Nakajima H, Iwamoto I, Yoshida S: Aerosolized recombinant interferon-gamma prevents antigen-induced eosinophil recruitment in mouse trachea. Am Rev Respir Dis 1993;148:1102-1104.
35. Ishihara C, Ochiai K, Kagami M, Takashahi H, Matsuyama G, Yoshida S, Tomioka H, Koya N: Human peripheral eosinophils express functional interferon-gamma receptors (IFN-gammaR). Clin Exp Immunol 1997;110:524-529.
36. Liu LY, Sedgwick JB, Bates ME, Vrtis RF, Gern JE, Kita H, Jarjour NN, Busse WW, Kelly EA: Decreased expression of membrane IL-5 receptor alpha on human eosinophils. II. IL-5 down-modulates its receptor via a proteinase-mediated process. J Immunol 2002;169:6459-6466.
37. Yasruel Z, Humbert M, Kotsimbos TC, Ploysongsang Y, Minshall E, Durham SR, Pfister R, Menz G, Tavernier J, Kay AB, Hamid Q: Membrane-bound and soluble alpha IL-5 receptor mRNA in the bronchial mucosa of atopic and nonatopic asthmatics. Am J Respir Crit Care Med 1997;155:1413-1418.