Manipulation of zebrafish embryogenesis by phosphorodiamidate morpholino oligomers indicates minimal non-specific teratogenesis

Current Opinion in Molecular Therapeutics

Volumn 7, Issue 2, 2005, Pages 104-108

  Iversen, Patrick L ^a   Newbry, Scott ^b  

^a AVI BIOPHARMA INC   (United States)

^b DARTMOUTH COLLEGE   (United States)

Author keywords

Developmental toxicity; Genotoxicity; Phosphorodiamidate morpholino oligomer; Teratogenesis

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; RIBAVIRIN;

DOSE RESPONSE; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXPOSURE; DRUG POTENCY; DRUG PURIFICATION; DRUG SAFETY; DRUG SCREENING; DRUG SYNTHESIS; EMBRYO DEATH; EMBRYO DEVELOPMENT; FETUS RISK; GENE TARGETING; GENOTOXICITY; HUMAN; INCIDENCE; NONHUMAN; PENETRANCE; PHENOTYPE; REVIEW; TERATOGENESIS; TERATOGENICITY; TOXICITY TESTING; ZEBRA FISH;

ABNORMALITIES, DRUG-INDUCED; ANIMALS; MORPHOLINES; ZEBRAFISH;

ANIMALIA; DANIO RERIO;

EID: 17144426046     PISSN: 14648431     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

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