-
1
-
-
0023245677
-
FK-506, A novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics
-
Kino T, Hatanaka H, Hashimoto M, Nishiyama M, Goto T, Okuhara M, Kohsaka M, Aoki H, Imanaka H. FK-506, A novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. J Antibiot (Tokyo). 1987;40:1249-1255.
-
(1987)
J Antibiot (Tokyo)
, vol.40
, pp. 1249-1255
-
-
Kino, T.1
Hatanaka, H.2
Hashimoto, M.3
Nishiyama, M.4
Goto, T.5
Okuhara, M.6
Kohsaka, M.7
Aoki, H.8
Imanaka, H.9
-
2
-
-
0023269998
-
Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation
-
Sawada S, Suzuki G, Kawase Y, Takaku F. Novel immunosuppressive agent, FK506. In vitro effects on the cloned T cell activation. J Immunol. 1987;139:1797-1803.
-
(1987)
J Immunol
, vol.139
, pp. 1797-1803
-
-
Sawada, S.1
Suzuki, G.2
Kawase, Y.3
Takaku, F.4
-
3
-
-
0024419167
-
FK 506 for liver, kidney, and pancreas transplantation
-
Starzl TE, Todo S, Fung J, Demetris AJ, Venkataramman R, Jain A. FK 506 for liver, kidney, and pancreas transplantation. Lancet. 1989;2(8670):1000-1004.
-
(1989)
Lancet
, vol.2
, Issue.8670
, pp. 1000-1004
-
-
Starzl, T.E.1
Todo, S.2
Fung, J.3
Demetris, A.J.4
Venkataramman, R.5
Jain, A.6
-
4
-
-
0023720788
-
Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats
-
Kawashima H, Fujino Y, Mochizuki M. Effects of a new immunosuppressive agent, FK506, on experimental autoimmune uveoretinitis in rats. Invest Ophthalmol Vis Sci. 1988;29:1265-1271.
-
(1988)
Invest Ophthalmol Vis Sci
, vol.29
, pp. 1265-1271
-
-
Kawashima, H.1
Fujino, Y.2
Mochizuki, M.3
-
5
-
-
0026784565
-
Preclinical and clinical study of FK506 in uveitis
-
Mochizuki M, Ikeda E, Shirao M, Fujito S, Yoshimura K, Shimada N. Preclinical and clinical study of FK506 in uveitis. Curr Eye Res. 1992;11(Suppl):87-95.
-
(1992)
Curr Eye Res
, vol.11
, Issue.SUPPL.
, pp. 87-95
-
-
Mochizuki, M.1
Ikeda, E.2
Shirao, M.3
Fujito, S.4
Yoshimura, K.5
Shimada, N.6
-
6
-
-
0026338195
-
A multicenter clinical open trial of FK 506 in refractory uveitis, including Behcet's disease
-
Japanese FK 506 Study Group on Refractory Uveitis
-
Mochizuki M, Masuda K, Sakane T, Inaba G, Ito K, Kogure M, Sugino N, Usui M, Mizushima Y, Ohno S, Miyanaga Y, Hayasaka S, Ohizumi K. A multicenter clinical open trial of FK 506 in refractory uveitis, including Behcet's disease. Japanese FK 506 Study Group on Refractory Uveitis. Transplant Proc. 1991;23:3343-3346.
-
(1991)
Transplant Proc
, vol.23
, pp. 3343-3346
-
-
Mochizuki, M.1
Masuda, K.2
Sakane, T.3
Inaba, G.4
Ito, K.5
Kogure, M.6
Sugino, N.7
Usui, M.8
Mizushima, Y.9
Ohno, S.10
Miyanaga, Y.11
Hayasaka, S.12
Ohizumi, K.13
-
7
-
-
0033498281
-
Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine
-
Sloper CM, Powell RJ, Dua HS. Tacrolimus (FK506) in the treatment of posterior uveitis refractory to cyclosporine. Ophthalmology. 1999;106:723-728.
-
(1999)
Ophthalmology
, vol.106
, pp. 723-728
-
-
Sloper, C.M.1
Powell, R.J.2
Dua, H.S.3
-
8
-
-
0037373677
-
Topical tacrolimus treatment of atopic eyelid disease
-
Rikkers SM, Holland GN, Drayton GE, Michel FK, Torres MF, Takahashi S. Topical tacrolimus treatment of atopic eyelid disease. Am J Ophthalmol. 2003;135:297-302.
-
(2003)
Am J Ophthalmol
, vol.135
, pp. 297-302
-
-
Rikkers, S.M.1
Holland, G.N.2
Drayton, G.E.3
Michel, F.K.4
Torres, M.F.5
Takahashi, S.6
-
9
-
-
0027937489
-
Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia
-
Sharkey J, Butcher SP. Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia. Nature. 1994;371:336-339.
-
(1994)
Nature
, vol.371
, pp. 336-339
-
-
Sharkey, J.1
Butcher, S.P.2
-
10
-
-
0027453536
-
Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
-
Dawson TM, Steiner JP, Dawson VL, Dinerman JL, Uhl GR, Snyder SH. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc Natl Acad Sci U S A. 1993;90:9808-9812.
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9808-9812
-
-
Dawson, T.M.1
Steiner, J.P.2
Dawson, V.L.3
Dinerman, J.L.4
Uhl, G.R.5
Snyder, S.H.6
-
11
-
-
0031807664
-
Tacrolimus(FK506) attenuates leukocyte accumulation after transient retinalischemia
-
Tsujikawa A, Ogura Y, Hiroshiba N, Miyamoto K, Kiryu J, Honda Y. Tacrolimus(FK506) attenuates leukocyte accumulation after transient retinalischemia. Stroke. 1998;29:1431-1438.
-
(1998)
Stroke
, vol.29
, pp. 1431-1438
-
-
Tsujikawa, A.1
Ogura, Y.2
Hiroshiba, N.3
Miyamoto, K.4
Kiryu, J.5
Honda, Y.6
-
12
-
-
0033537768
-
Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD
-
Wang HG, Pathan N, Ethell IM, Krajewski S, Yamaguchi Y, Shibasaki F, McKeon F, Bobo T, Franke TF, Reed JC. Ca2+-induced apoptosis through calcineurin dephosphorylation of BAD. Science. 1999;284:339-343.
-
(1999)
Science
, vol.284
, pp. 339-343
-
-
Wang, H.G.1
Pathan, N.2
Ethell, I.M.3
Krajewski, S.4
Yamaguchi, Y.5
Shibasaki, F.6
McKeon, F.7
Bobo, T.8
Franke, T.F.9
Reed, J.C.10
-
13
-
-
0036403825
-
Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition
-
Uchino H, Minamikawa-Tachino R, Kristian T, Perkins G, Narazaki M, Siesjo BK, Shibasaki F. Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis. 2002;10:219-233.
-
(2002)
Neurobiol Dis
, vol.10
, pp. 219-233
-
-
Uchino, H.1
Minamikawa-Tachino, R.2
Kristian, T.3
Perkins, G.4
Narazaki, M.5
Siesjo, B.K.6
Shibasaki, F.7
-
14
-
-
0037424434
-
Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: Dose dependency, therapeutic time window and long-term efficacy
-
Furuichi Y, Katsuta K, Maeda M, Ueyama N, Moriguchi A, Matsuoka N, Goto T, Yanagihara T. Neuroprotective action of tacrolimus (FK506) in focal and global cerebral ischemia in rodents: Dose dependency, therapeutic time window and long-term efficacy. Brain Res. 2003;965:137-145.
-
(2003)
Brain Res
, vol.965
, pp. 137-145
-
-
Furuichi, Y.1
Katsuta, K.2
Maeda, M.3
Ueyama, N.4
Moriguchi, A.5
Matsuoka, N.6
Goto, T.7
Yanagihara, T.8
-
15
-
-
0034034811
-
The effects of FK506 on retinal ganglion cells after optic nerve crush
-
Freeman EE, Grosskreutz CL. The effects of FK506 on retinal ganglion cells after optic nerve crush. Invest Ophthalmol Vis Sci. 2000;41:1111-1115.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 1111-1115
-
-
Freeman, E.E.1
Grosskreutz, C.L.2
-
16
-
-
0031806507
-
Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture
-
Kikuchi M, Kashii S, Mandai M, Yasuyoshi H, Honda Y, Kaneda K, Akaike A. Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture. Invest Ophthalmol Vis Sci. 1998;39:1227-1232.
-
(1998)
Invest Ophthalmol Vis Sci
, vol.39
, pp. 1227-1232
-
-
Kikuchi, M.1
Kashii, S.2
Mandai, M.3
Yasuyoshi, H.4
Honda, Y.5
Kaneda, K.6
Akaike, A.7
-
17
-
-
0025088216
-
Immune mechanisms in choroido-retinal inflammation in man
-
Lightman S, Chan CC. Immune mechanisms in choroido-retinal inflammation in man. Eye. 1990;4:345-353.
-
(1990)
Eye
, vol.4
, pp. 345-353
-
-
Lightman, S.1
Chan, C.C.2
-
18
-
-
0028930675
-
Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat
-
Hikita N, Chan CC, Whitcup SM, Nussenblatt RB, Mochizuki M. Effects of topical FK506 on endotoxin-induced uveitis (EIU) in the Lewis rat. Curr Eye Res. 1995;14:209-214.
-
(1995)
Curr Eye Res
, vol.14
, pp. 209-214
-
-
Hikita, N.1
Chan, C.C.2
Whitcup, S.M.3
Nussenblatt, R.B.4
Mochizuki, M.5
-
19
-
-
0033761752
-
Fluocinolone acetonide sustained drug delivery device to treat severe uveitis
-
Jaffe GJ, Ben-Nun J, Guo H, Dunn JP, Ashton P. Fluocinolone acetonide sustained drug delivery device to treat severe uveitis. Ophthalmology. 2000;107:2024-2033.
-
(2000)
Ophthalmology
, vol.107
, pp. 2024-2033
-
-
Jaffe, G.J.1
Ben-Nun, J.2
Guo, H.3
Dunn, J.P.4
Ashton, P.5
-
20
-
-
0035113020
-
Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis
-
Young S, Larkin G, Branley M, Lightman S. Safety and efficacy of intravitreal triamcinolone for cystoid macular oedema in uveitis. Clin Exp Ophthalmol. 2001;29:2-6.
-
(2001)
Clin Exp Ophthalmol
, vol.29
, pp. 2-6
-
-
Young, S.1
Larkin, G.2
Branley, M.3
Lightman, S.4
-
21
-
-
0023205091
-
A highly sensitive method to assay FK-506 levels in plasma
-
Tamura K, Kobayashi M, Hashimoto K, Kojima K, Nagase K, Iwasaki K, Kaizu T, Tanaka H, Niwa M. A highly sensitive method to assay FK-506 levels in plasma. Transplant Proc. 1987;19(5 Suppl 6):23-29.
-
(1987)
Transplant Proc
, vol.19
, Issue.5 SUPPL. 6
, pp. 23-29
-
-
Tamura, K.1
Kobayashi, M.2
Hashimoto, K.3
Kojima, K.4
Nagase, K.5
Iwasaki, K.6
Kaizu, T.7
Tanaka, H.8
Niwa, M.9
-
22
-
-
0014736536
-
Correlation between ocular inflammation and antibody production. I. Serum antibody response following intravitreal immunization with protein antigens
-
Hall JM, O'Connor GR. Correlation between ocular inflammation and antibody production. I. Serum antibody response following intravitreal immunization with protein antigens. J Immunol. 1970;104:432-439.
-
(1970)
J Immunol
, vol.104
, pp. 432-439
-
-
Hall, J.M.1
O'Connor, G.R.2
-
23
-
-
84965031009
-
Signs and symptoms of uveitis. I. AnteriorUveitis
-
Hogan MJ, Kimura SM, Thygeson P. Signs and symptoms of uveitis. I. AnteriorUveitis. Am J Ophthalmol. 1959;47:171-180.
-
(1959)
Am J Ophthalmol
, vol.47
, pp. 171-180
-
-
Hogan, M.J.1
Kimura, S.M.2
Thygeson, P.3
-
24
-
-
0031893747
-
Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis
-
Jaffe GJ, Yang CS, Wang XC, Cousins SW, Gallemore RP, Ashton P. Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis. Ophthalmology. 1998;105:46-56.
-
(1998)
Ophthalmology
, vol.105
, pp. 46-56
-
-
Jaffe, G.J.1
Yang, C.S.2
Wang, X.C.3
Cousins, S.W.4
Gallemore, R.P.5
Ashton, P.6
-
25
-
-
0027483929
-
Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis
-
Caspi RR, Chan CC, Fujino Y, Najafian F, Grover S, Hansen CT, Wilder RL. Recruitment of antigen-nonspecific cells plays a pivotal role in the pathogenesis of a T cell-mediated organ-specific autoimmune disease, experimental autoimmune uveoretinitis. J Neuroimmunol. 1993;47:177-188.
-
(1993)
J Neuroimmunol
, vol.47
, pp. 177-188
-
-
Caspi, R.R.1
Chan, C.C.2
Fujino, Y.3
Najafian, F.4
Grover, S.5
Hansen, C.T.6
Wilder, R.L.7
-
26
-
-
0028862312
-
Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents
-
Sartani G, Silver PB, Strassmann G, Chan CC, Caspi RR. Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents. Curr Eye Res. 1995;14:887-896.
-
(1995)
Curr Eye Res
, vol.14
, pp. 887-896
-
-
Sartani, G.1
Silver, P.B.2
Strassmann, G.3
Chan, C.C.4
Caspi, R.R.5
-
27
-
-
0026076156
-
Quantitation of ischemic damage in the rat retina
-
Hughes WF. Quantitation of ischemic damage in the rat retina. Exp Eye Res. 1991;53:573-582.
-
(1991)
Exp Eye Res
, vol.53
, pp. 573-582
-
-
Hughes, W.F.1
-
29
-
-
0028965865
-
Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity
-
Conde M, Andrade J, Bedoya FJ, Santa Maria C, Sobrino F. Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity. Immunology. 1995;84:476-481.
-
(1995)
Immunology
, vol.84
, pp. 476-481
-
-
Conde, M.1
Andrade, J.2
Bedoya, F.J.3
Santa Maria, C.4
Sobrino, F.5
-
30
-
-
0018374457
-
Vitrectomy in experimental uveitis. I. Operative technique in rabbits
-
Kaplan HJ, Diamond JG, Brown SA. Vitrectomy in experimental uveitis. I. Operative technique in rabbits. Arch Ophthalmol. 1979;97:331-335.
-
(1979)
Arch Ophthalmol
, vol.97
, pp. 331-335
-
-
Kaplan, H.J.1
Diamond, J.G.2
Brown, S.A.3
-
31
-
-
0142139213
-
Scieral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis
-
Sakurai E, Nozaki M, Okabe K, Kunou N, Kimura H, Ogura Y. Scieral plug of biodegradable polymers containing tacrolimus (FK506) for experimental uveitis. Invest Ophthalmol Vis Sci. 2003;44:4845-4852.
-
(2003)
Invest Ophthalmol Vis Sci
, vol.44
, pp. 4845-4852
-
-
Sakurai, E.1
Nozaki, M.2
Okabe, K.3
Kunou, N.4
Kimura, H.5
Ogura, Y.6
|