The development of molecular biological study of depression

Chinese Pharmacological Bulletin

Volumn 21, Issue 2, 2005, Pages 138-140

  Yan, Bin ^a   Du, Li Jun ^b  

^a INSTITUTE OF MEDICINAL PLANT DEVELOPMENT   (China)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

Depression; Molecular biology; The second message

Indexed keywords

ANTIDEPRESSANT AGENT; ROLIPRAM;

ARTICLE; DEPRESSION; HUMAN; MOLECULAR BIOLOGY; NEUROTRANSMISSION; PATHOGENESIS; SIGNAL TRANSDUCTION;

EID: 17144424947     PISSN: 10011978     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Young LT, Li PP, Kish SJ et al. Cerebral cortex Gs alpha protein levels and forskolin-stimulated cyclic AMP formation are increased in bipolar affective disorder[J]. J Neurochem, 1993, 61(3):890 -8.
2. Mitchell PB, Manji HK, Chen G et al. High levels of Gs alpha in platelets of euthymic patients with bipolar affective disorder[J]. Am J Psychiatry, 1997, 154(2):218-23.
3. Sulser F. Antidepressant treatments and regulation of norepinephrinereceptor-coupled adenylate cyclase systems in brain[J]. Adv Biochem Psychopharmacol, 1984, 39:249-61.
4. Lesch KP, Manji HK. Signal-transducing G proteins and antidepressant drugs: Evidence for modulation of alpha subunit gene expression in rat brain[J]. Biol Psychiatry, 1992, 32(7):549-79.
5. Tiong AH, Richardson JS. Beta-adrenoceptor and post-receptor components show different rates of desensitization to desipramine [J]. Eur J Pharmacol, 1990, 188(6):411-5.
6. Ebstein RP, Lerer B, Shapira B et al. Cyclic AMP second-messenger signal amplification in depression[J]. Br J Psychiatry, 1988, 152:665-9.
7. Ebstein RP, Oppenheim G, Ebstein BS et al. The cyclic AMP second messenger system in man: The effects of heredity, hormones, drugs, aluminum, age and diseaseon signal amplification[J]. Prog Neuropsychopharmacol Biol Psychiatry, 1986, 10(3-5):323-53.
8. Pandey GN, Dysken MW, Carver DL et al. Beta-adrenergic receptor function in affective illness[J]. Am J Psychiatry, 1979, 136 (5):675-8.
9. Nibuya M, Nestler EJ, Duman RS. Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus[J]. J Neurosci, 1996, 16 (7):2365-72.
10. Dowlatshahi D, MacQueen GM, Wang JF et al. Increased temporal cortex CREB concentrations and antidepressant treatment in major depression[J]. Lancet, 1998, 352(9142):1754-5.
11. Wang HY, Friedman E. Enhanced protein kinase C activity and translocation in bipolar affective disorder brains[J]. Biol Psychiatry, 1996, 40(7):568-75.
12. Jope RS, Song L, Li PP et al. The phosphoinositide signal transduction system is impaired in bipolar affective disorder brain[J]. J Neurochem, 1996, 66(6):2402-9.
13. Manji HK, Potter WZ, Lenox RH. Signal transduction pathways. Molecular targets for lithium's actions[J]. Arch Gen Psychiatry, 1995, 52(7):531-43.
14. McNamara RK, Lenox RH. Distribution of the protein kinase C substrates MARCKS and MRP in the postnatal developing rat brain [J]. J Comp Neurol, 1998, 397(3):337-56.
15. Nishizuka Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C[J]. Science, 1992, 258(5082): 607-14.
16. Stabel S, Parker PJ. Protein kinase C[J]. Pharmacol Ther, 1991, 51(1):71-95.
17. Wang HY, Friedman E. Lithium inhibition of protein kinase C activation-induced serotonin release[J]. Psychopharmacology, 1989, 99(2):213-8.
18. Yuan PX, Chen G, Huang LD et al. Lithium stimulates gene expression through the AP-1 transcription factor pathway[J]. Brain Res Mol Brain Res, 1998, 58(1-2):225-30.
19. Chen G, Yuan PX, Jiang YM et al. Lithium increases tyrosine hydroxylase levels both in vivo and in vitro[J]. J Neurochem, 1998, 70(4);1768-71.
20. Duman RS. Novel therapeutic approaches beyond the serotonin receptor[J]. Biol Psychiatry, 1998, 44(5):324-35.
21. Chen AC, Shirayama Y, Shin KH et al. Expression of the cAMP response element binding protein (CREB) in hippocampus produces an antidepressant effect[J]. Biol Psychiatry, 2001, 49(9): 753-62.
22. Takahashi M, Terwilliger R, Lane C et al. Chronic antidepressant administration increases the expression of cAMP phosphodiesterase 4A and 4B isoforms[J]. J Neurosci, 1999, 19(2):610-8