Novel quinolinequinone antitumor agents: Structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1)

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 15, 1999, Pages 2195-2198

  Fryatt, Tara ^a   Goroski, Dean T ^b   Nilson, Zachary D ^b   Moody, Christopher J ^a   Beall, Howard D ^b  

^a UNIVERSITY OF EXETER   (United Kingdom)

^b UNIVERSITY OF MONTANA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FUNCTIONAL GROUP; QUINOLINEQUINONE; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; DRUG DESIGN; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANTINEOPLASTIC AGENTS; HUMANS; NADH, NADPH OXIDOREDUCTASES; QUINOLONES; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY;

EID: 0033517085     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00369-8     Document Type: Article

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