Evolutionary chemistry approach toward finding novel inhibitors of the type 2 diabetes target glucose-6-phosphate translocase

Journal of Combinatorial Chemistry

Volumn 7, Issue 2, 2005, Pages 218-226

  Bräuer, Silke ^a   Almstetter, Michael ^a   Antuch, Walfrido ^a   Behnke, Dirk ^a   Taube, Roswitha ^a   Furer, Patrick ^a   Hess, Sibylle ^a  

^a Biovertis AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; GLUCOSE 6 PHOSPHATE; IMIDAZOLE DERIVATIVE; POLYMER;

ACYLATION; AMINATION; ARTICLE; BIOLOGICAL ACTIVITY; ENZYME ACTIVITY; ENZYME ASSAY; FILTER; GENETIC ALGORITHM; IC 50; MICROSOME; MOLECULE; MUTATION RATE; NON INSULIN DEPENDENT DIABETES MELLITUS; STRUCTURE ACTIVITY RELATION; SULFONATION; SYNTHESIS;

ANIMALS; ANTIPORTERS; DIABETES MELLITUS, TYPE 2; ENZYME INHIBITORS; GLUCOSE; GLUCOSE-6-PHOSPHATASE; HUMANS; HYPOGLYCEMIC AGENTS; MICROSOMES, LIVER; MOLECULAR STRUCTURE; MONOSACCHARIDE TRANSPORT PROTEINS; RATS;

EID: 17144394101     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc049867+     Document Type: Article

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