Clinical characteristics of Type 2 diabetes mellitus in overweight European Caucasian adolescents

Experimental and Clinical Endocrinology and Diabetes

Volumn 113, Issue 3, 2005, Pages 167-170

  Reinehr, Thomas ^a   Andler, W ^a   Kapellen, T ^b   Kiess, W ^b   Richter Unruh, A ^c   Schonau E ^d   Seewi, O ^d   Heinze, E ^e   Wabitsch, M ^e  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

^d UNIVERSITY OF COLOGNE   (Germany)

^e UNIVERSITY OF ULM   (Germany)

Author keywords

Adolescents; Clinical manifestation; European Caucasian; Type 2 diabetes

Indexed keywords

C PEPTIDE; GLUCOSE; HEMOGLOBIN A1C; INSULIN;

ACANTHOSIS NIGRICANS; ADOLESCENT; ARTICLE; CLINICAL ARTICLE; CLINICAL FEATURE; DIAGNOSTIC PROCEDURE; DYSLIPIDEMIA; EUROPEAN AMERICAN; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; INSULIN RESISTANCE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; ORAL GLUCOSE TOLERANCE TEST; POLYURIA; PRIORITY JOURNAL;

ACANTHOSIS NIGRICANS; ADOLESCENT; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; HYPERLIPIDEMIAS; HYPERTENSION; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN RESISTANCE; MALE; METABOLIC SYNDROME X; OBESITY; POLYURIA; PUBERTY;

EID: 17144377462     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-837522     Document Type: Article

References (24)

1. Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 1998; 15: 539-553
2. Allard P, Delvin EE, Paradis G, Hanley JA, O'Loughlin J, Lavallee C, Levy E, Lambert M. Distribution of fasting plasma insulin, free fatty acids, and glucose concentrations and of homeostasis model assessment of insulin resistance in a representative sample of Quebec children and adolescents. Clinical Chemistry 2003; 49: 644-649
3. American Academy of Pediatrics. National Cholesterol Education Program: Report of the Expert Panel on Blood Cholesterol Levels in Children and Adolescents. Pediatrics 1992; 89: 525-584
4. American Diabetes Association. Type 2 diabetes in children and adolescents. Diab Care 2000; 23: 381-389
5. Arslanian SA, Kalhan SC. Correlation between fatty acid and glucose metabolism: potential explanation of insulin resistance of puberty. Diabetes 1994; 43: 908-914
6. Arslanian SA, Suprasongsin C. Differences in the in vivo insulin secretion and sensitivity in healthy black versus white adolescents. J Pediatr 1996; 129: 440-444
7. Arslanian SA. Type 2 diabetes in children: Clinical aspects and risk factors. Horm Res 2002; 57(Suppl 1): 19-28
8. DCCT Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. New Engl J Med 1993; 329: 977-986
9. Drake AJ, Smith A, Betts PR, Crowne EC, Shield JP. Type 2 diabetes in obese white children. Arch Dis Child 2002; 86: 207-208
10. Ebbeling CA, Pawlak DB, Ludwig DS. Childhood obesity: public-health crisis, common sense cure. Lancet 2002; 360: 473-482
11. Fagot-Campagna A, Pettitt DJ, Engelgau MM, Burrows NR, Geiss LS, Valdez R, Beckles GL, Saaddine J, Gregg EW, Williamson DF, Narayan KM. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr 2000; 136: 664-672
12. Glaser NS. Non-insulin-dependent diabetes mellitus in childhood and adolescence. Pediatr Clin North Am 1997; 44: 303-337
13. Kapellen TM, Böttner A, Galler A, Raile K, Nietzschmann U, Kiess W. Treatment of adolescents with type 2 diabetes. Klin Padiatr 2004; 216: 57-61
14. Kiess W, Bottner A, Raile K, Kapellen T, Muller G, Galler A, Paschke R, Wabitsch M. Type 2 diabetes mellitus in children and adolescents: a review from a European perspective. Horm Res 2003; 59 (Suppl 1): 77-84
15. Kromeyer-Hauschild K, Wabitsch M, Geller F, Ziegler A, Geiß HC, Hesse V, v. Hippel, Jaeger U, Johnsen D, Kiess W, Korte W, Kunze D, Menner K, Müller M, Niemann-Pilatus A, Remer Th, Schaefer F, Wittchen HU, Zabransky S, Zellner K, Hebebrand J. Percentiles of body mass index in children and adolescents evaluated from different regional German studies. Monatsschr Kinderheilkd 2001; 149: 807-818
16. Makovi H, Soltesz G, Hermann R. Clinical heterogeneity of childhood diabetes in Baranya county. Orv Hetil 2002; 143: 2489-2492
17. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-419
18. Rami B, Schober E, Nachbauer E, Waldhör T. Type 2 diabetes mellitus is rare but not absent in children under 15 years of age in Austria. Eur J Ped 2003; 162: 850-852
19. Reaven GM, Hoffman BB. A role for insulin in the aetiology and course of hypertension? Lancet 1987; 2: 435-437
20. Rosner B, Prineas RJ, Loggie JM, Daniels. Blood pressure normograms for children and adolescents by height, sex, and age, in the United States. J Pediatr 1993; 123: 871-886
21. Sinha R, Fisch G, Teague B, Tamborlane WV, Banyas B, Allen K, Savoye M, Rieger V, Taksali S, Barbetta G, Sherwin RS, Caprio S. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Eng J Med 2002; 346: 802-810
22. Stratton IM, Adler AI, Neil HA, Matthews DR, Manley SE, Cull CA, Hadden D, Turner RC, Holman RR. Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study. BMJ 2000; 321: 405-412
23. Velho G, Froguel P. Genetic metabolic and clinical characteristics of maturity onset diabetes of the young. Eur J Endocrinol 1998; 138: 233-239
24. Wabitsch M, Hauner H, Hertrampf M, Muche R, Hay B, Mayer H, Kratzer W, Debatin KM, Heinze E. Type 2 diabetes mellitus and impaired glucose regulation in Caucasian children and adolescents with obesity living in Germany. Int J Obes Relat Metab Disord 2004; 28: 307-313