13-cis Retinoic acid and isomerisation in paediatric oncology - Is changing shape the key to success?

Biochemical Pharmacology

Volumn 69, Issue 9, 2005, Pages 1299-1306

  Armstrong, Jane L ^a   Redfern, Christopher P F ^a   Veal, Gareth J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

Isomerisation; Metabolism; Neuroblastoma; Paediatric; Pro drug; Retinoic acid

Indexed keywords

ALBUMIN; ALITRETINOIN; BAG 1 PROTEIN; CYCLODEXTRIN; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; FLUCONAZOLE; ISOTRETINOIN; KETOCONAZOLE; LIAROZOLE; PRODRUG; R 116010; RETINOIC ACID; RETINOIC ACID BINDING PROTEIN; RETINOIC ACID BINDING PROTEIN I; RETINOIC ACID BINDING PROTEIN II; RETINOIC ACID RECEPTOR; RETINOID X RECEPTOR; SOMATOMEDIN BINDING PROTEIN 3; UNCLASSIFIED DRUG; VERAPAMIL;

ABDOMINAL PAIN; BINDING AFFINITY; BIOLOGICAL ACTIVITY; BRAIN PSEUDOTUMOR; CANCER INHIBITION; CANCER SURVIVAL; CANCER THERAPY; CELL METABOLISM; CELL TRANSPORT; CLINICAL TRIAL; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG EFFICACY; DRUG MEGADOSE; DRUG METABOLISM; DRUG POTENTIATION; DRUG RECEPTOR BINDING; DRUG TOLERABILITY; DRUG UPTAKE; GENE EXPRESSION; HEADACHE; HUMAN; INTERMETHOD COMPARISON; ISOMER; ISOMERIZATION; LIVER TOXICITY; NAUSEA; NEUROBLASTOMA; NONHUMAN; ONCOLOGY; PEDIATRICS; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROSTATE CANCER; REVIEW; STEREOSPECIFICITY; SURVIVAL RATE; SURVIVAL TIME; TREATMENT PLANNING; TUMOR CELL; VOMITING; XEROSIS;

EID: 17144374443     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2005.02.003     Document Type: Note

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