Vasculoprotective role of inducible nitric oxide synthase at inflammatory coronary lesions induced by chronic treatment with interleukin- 1β in pigs in vivo

Circulation

Volumn 96, Issue 9, 1997, Pages 3104-3111

  Fukumoto, Yoshihiro ^b   Shimokawa, Hiroaki ^a   Kozai, Toshiyuki ^b   Kadokami, Toshiaki ^b   Kuwata, Kouichi ^b   Yonemitsu, Yoshikazu ^a   Kuga, Takeshi ^b   Egashira, Kensuke ^b   Sueishi, Katsuo ^a   Takeshita, Akira ^b  

^a KYUSHU UNIVERSITY   (Japan)

^b NONE

Author keywords

Arteriosclerosis; Endothelium derived factors; Nitric oxide synthase; Vasospasm

Indexed keywords

AMINOGUANIDINE; INTERLEUKIN 1BETA; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIOSCLEROSIS; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY SPASM; ENZYME INDUCTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 17044442512     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.96.9.3104     Document Type: Article

References (43)

1. Maseri A, Severi S, DeNes DM, L'Abbate A, Chierchia S, Marzilli M, Ballestra AM, Parodi O, Biagini A, Distante A. 'Variant' angina: one aspect of a continuous spectrum of vasospastic myocardial ischemia: pathogenetic mechanisms, estimated incidence and clinical and coronary angiographic findings in 138 patients. Am J Cardiol. 1978;42:1019-1035.
2. Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes, I. N Engl J Med. 1992;326:242-250.
3. Shimokawa H, Tomoike H, Nabeyama S, Yamamoto H, Araki H, Nakamura M, Ishii Y, Tanaka K. Coronary artery spasm induced in atherosclerotic miniature swine. Science. 1983;221:560-562.
4. Shimokawa H, Tomoike H, Nabeyama S, Yamamoto H, Ishii Y, Tanaka K, Nakamura M. Coronary artery spasm induced in miniature swine: angiographic evidence and relation to coronary atherosclerosis. Am Heart J. 1985;110:300-310.
5. Egashira K, Tomoike H, Yamamoto Y, Yamada A, Hayashi Y, Nakamura M. Histamine-induced coronary spasm in regions of intimai thickening in miniature pigs: roles of serum cholesterol and spontaneous or induced intimal thickening. Circulation. 1986;74: 826-837.
6. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1990s. Nature. 1993;362:801-809.
7. Munro JM, Cotran RS. Biology of disease: the pathogenesis of atherosclerosis: atherogenesis and inflammation. Lab Invest. 1988; 58:249-261.
8. Hannson GK, Jonasson L, Seifert PS, Stemme S. Immune mechanisms in atherosclerosis. Arteriosclerosis. 1989;9:567-578.
9. Libby P, Warner SJC, Friedman G. Interleukin 1: a mitogen for human vascular smooth muscle cells that induces the release of growth-inhibitory prostanoids. J Clin Invest. 1988;81:487-498.
10. Shimokawa H, Ito A, Fukumoto Y, Kadokami T, Nakaike R, Sakata M, Takayanagi T, Egashira K, Takeshita A. Chronic treatment with interleukin-1β induces coronary intimai lesions and vasospastic responses in pigs in vivo: the role of platelet-derived growth factor. J Clin Invest. 1996;97:769-776.
11. Ito A, Shimokawa H, Kadokami T, Fukumoto Y, Owada MK, Shiraishi T, Nakaike R, Takayanagi T, Egashira K, Takeshita A. Tyrosine kinase inhibitor suppresses coronary arteriosclerotic changes and vasospastic responses induced by chronic treatment with interleukin-1β in pigs in vivo. J Clin Invest. 1995;96:1288-1294.
12. Shibano T, Vanhoutte PM. Induction of NO production by TNF-α and lipopolysaccharide in porcine coronary arteries without endothelium. Am J Physiol. 1993;264:H403-H407.
13. Kanno K, Hirata Y, Imai T, Marumo F. Induction of nitric oxide synthase gene by interleukin in vascular smooth muscle cells. Hypertension. 1993;22:34-39.
14. Liu S, Adcock IM, Old RW, Barnes PJ, Evans TW. Lipopolysaccharide treatment in vivo induces widespread tissue expression of inducible nitric oxide synthase mRNA. Biochem Biophys Res Commun. 1993;196:1208-1213.
15. Tsujino M, Hirata Y, Imai T, Kanno K, Eguchi S, Ito H, Marumo F. Induction of nitric oxide synthase gene by interleukin-1β in cultured rat cardiocytes. Circulation. 1994;90:375-383.
16. Anggard E. Nitric oxide: mediator, murderer, and medicine. Lancet. 1994;343:1199-1206.
17. Petros A, Vennett D, Vallance P. Effects of nitric oxide synthase inhibitors on hypotension in patients with septic shock. Lancet. 1991;338:1557-1558.
18. Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med. 1993;328:1471-1477.
19. Moncada S, Higgs EA. Molecular mechanisms and therapeutic strategies related to nitric oxide. FASEB J. 1995;9:1319-1330.
20. Shimokawa H, Takeshita A. Endothelium-dependent regulation of the cardiovascular system. Intern Med. 1995;34:939-946.
21. Yoshizumi M, Perrella MA, Burnett JC Jr, Lee ME. Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. J Biol Chem. 1993;73:205-209.
22. Misko TP, Moore WM, Kasten TP, Nickols GA, Corbett JA, Tilton RG, McDaniel ML, Williamson JR, Currie MG. Selective inhibition of the inducible nitric oxide synthase by aminoguanidine. Eur J Pharmacol. 1993;233:119-125.
23. Hasan K, Heesen BJ, Corbett JA, McDaniel ML, Chang K, Allison W, Wolffenbuttel BHR, Williamson JR, Tilton RG. Inhibition of nitric oxide formation by guanidines. Eur J Pharmacol. 1993;249: 101-106.
24. Hsu SM, Raine L, Fanger H. Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques. J Histochem Cytochem. 1981;29:577-580.
25. Shimokawa H, Flavahan NA, Vanhoutte PM. Loss of endothelial pertussis toxin - sensitive G-protein function in atherosclerotic porcine coronary arteries. Circulation. 1991;83:652-660.
26. Corbett JA, Tilton RG, Chang K, Hasan KS, Ido Y, Wang JI, Sweetland MA, Lancaster JR, Williamson JR, McDaniel MI. Aminoguanidine, a novel inhibitor of nitric oxide formation, prevents diabetic vascular dysfunction. Diabetes. 1992;41:552-556.
27. Kanno K, Hirata Y, Imai T, Iwashina M, Marumo F. Regulation of inducible nitric oxide synthase gene by interleukin-1β in rat vascular endothelial cells. Am J Physiol. 1994;267:H2318-H2324.
28. Nakayama I, Lawahara Y, Tsuda T. Angiotensin II inhibits cytokine-stimulated inducible nitric oxide synthase expression in vascular smooth muscle cells. J Biol Chem. 1994;269:11628-11633.
29. Coyne DW, Nickols M, Bertland W, Morrison AR. Regulation of mesangial cell cyclooxygenase synthesis by cytokines and glucocorticoids. Am J Physiol. 1992;263:F97-F102.
30. Corbett JA, Kwon G, Turk J, McDaniel ML. IL-1β induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide. Biochemistry. 1993;32:13767-13770.
31. Futaki N, Takahashi S, Yokoyama M, Arai I, Higuchi S, Otomo S. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins. 1994;47:55-59.
32. Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest. 1989;83:1774-1777.
33. McNamara DB, Bedi B, Aurora H, Tena L, Ignarro LJ, Kadowitz PJ, Akers DL. L-Arginine inhibits balloon catheter-induced intimal hyperplasia. Biochem Biophys Res Commun. 1993;193:291-296.
34. Hamon M, Vallet B, Bauters C, Wernert N, McFadden EP, Lablance JM, Dupuis B, Bertrand ME. Long-term oral administration of L-arginine reduces intimai thickening and enhances neoendothelium-dependent acetylcholine-induced relaxation after arterial injury. Circulation. 1994;90:1357-1362.
35. Tarry WC, Makhoul RG. L-Arginine improves endothelium-dependent vasorelaxation and reduces intimai hyperplasia after balloon angioplasty. Arterioscler Thromb. 1994;14:938-943.
36. Naruse K, Shimizu K, Muramatsu M, Toki M, Miyazaki Y, Okumura K, Hashimoto H, Ito T. Long-term inhibition of NO synthesis promotes atherosclerosis in the hypercholesterolemic rabbit thoracic aorta: PGH2 does not contribute to impaired endothelium-dependent relaxation. Arterioscler Thromb. 1994;14: 746-752.
37. Cayatte AJ, Palacino JJ, Hotton K, Cohen RA. Chronic inhibition of nitric oxide production accelerates neointima formation and impairs endothelial function in hypercholesterolemic rabbits. Arterioscler Thromb. 1994;14:753-759.
38. Joly GA, Schini VB, Vanhoutte PM. Balloon injury induces nitric oxide synthase activity in rat carotid arteries. J Cardiovasc Pharmacol. 1992;20:S151-S154.
39. Ito A, Shimokawa H, Nakaike R, Fukai T, Sakata M, Takayanagi T, Egashira K, Takeshita A. Role of protein kinase C-mediated pathway in the pathogenesis of coronary artery spasm in a swine model. Circulation. 1994;90:2425-2431.
40. Kadokami T, Shimokawa H, Fukumoto Y, Ito A, Takayanagi T, Egashira K, Takeshita A. Coronary artery spasm does not depend on the intracellular calcium store but is substantially mediated by the protein kinase C-mediated pathway in a swine model with interleukin-1β in vivo. Circulation. 1996;94:190-196.
41. Fukumoto Y, Shimokawa H, Ito A, Kadokami T, Yonemitsu Y, Aikawa M, Owada MK, Egashira K, Sueishi K, Nagai R, Yazaki Y, Takeshita A. Inflammatory cytokines cause coronary arteriosclerosis-like changes and alterations in the smooth-muscle phenotypes in pigs. J Cardiovasc Pharmacol. 1997;29:222-231.
42. Katsumata N, Shimokawa H, Seto M, Kozai T, Yamawaki T, Kuwata K, Egashira K, Ikegaki I, Asano T, Sasaki Y, Takeshita A. Enhanced rayosin light chain phosphorylations as a central mechanism for coronary artery spasm with interleukin-1β. Circulation. In press.
43. Fukumoto Y, Shimokawa H, Kozai T, Kadokami T, Kuwata K, Owada MK, Shiraishi T, Kuga T, Egashira K, Takeshita A. Tyrosine kinase inhibitor suppresses the (re)stenotic changes of the coronary artery after balloon injury in pigs. Cardiovasc Res. 1996;32: 1131-1140.