Transgenic mouse model of tau pathology in astrocytes leading to nervous system degeneration

Journal of Neuroscience

Volumn 25, Issue 14, 2005, Pages 3539-3550

  Forman, Mark S ^a   Lal, Devika ^a   Zhang, Bin ^a   Dabir, Deepa V ^a   Swanson, Eric ^a   Lee, Virginia M Y ^a   Trojanowski, John Q ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Astrocytes; Blood brain barrier; Neurodegeneration; Tau protein; Tauopathy; Transgenic mice

Indexed keywords

DIRECT YELLOW 7; GLIAL FIBRILLARY ACIDIC PROTEIN; HEAT SHOCK PROTEIN; TAU PROTEIN; THIOFLAVINE; UNCLASSIFIED DRUG;

AGE; ANIMAL TISSUE; ARTICLE; ASTROCYTE; AUTOSOMAL DOMINANT DISORDER; BLOOD BRAIN BARRIER; BRAIN REGION; CELL INCLUSION; CHROMOSOME 17; CONTROLLED STUDY; FAMILIAL DISEASE; FRONTOTEMPORAL DEMENTIA; GENE MUTATION; GENETIC LINKAGE; GLIA; HUMAN; MOUSE; NERVE DEGENERATION; NEUROPATHOLOGY; NONHUMAN; ONSET AGE; PARKINSONISM; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN AGGREGATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; TAUOPATHY; TRANSGENIC MOUSE; UBIQUITINATION;

AGE FACTORS; ANIMALS; ASTROCYTES; AXONS; BLOOD-BRAIN BARRIER; BLOTTING, WESTERN; BRAIN; DISEASE MODELS, ANIMAL; GENE EXPRESSION; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, TRANSGENIC; MICROSCOPY, IMMUNOELECTRON; NERVE DEGENERATION; NEUROFIBRILLARY TANGLES; NEUROFILAMENT PROTEINS; TAU PROTEINS; UBIQUITIN;

EID: 17044411592     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0081-05.2005     Document Type: Article

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