메뉴 건너뛰기




Volumn 234, Issue 1-2, 2005, Pages 117-126

Multiple sites of tumorigenesis in transgenic mice overproducing hCG

Author keywords

Choriongonadotropin; Leydig cell adenoma; Luteoma; Mammary tumours; Ovarian tumours; Pituitary tumours; Prolactinoma; Teratoma; Transgenic mice

Indexed keywords

CHORIONIC GONADOTROPIN; LUTEINIZING HORMONE; PROLACTIN; PROTEIN SUBUNIT; SEX HORMONE; UBIQUITIN C;

EID: 17044391004     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2004.10.013     Document Type: Conference Paper
Times cited : (29)

References (57)
  • 1
    • 0033304643 scopus 로고    scopus 로고
    • Chronic hypersecretion of luteinizing hormone in transgenic mice selectively alters responsiveness of the α-subunit gene to gonadotropin-releasing hormone and estrogens
    • R.A. Abbud, R.K. Ameduri, J.S. Rao, T.M. Nett, and J.H. Nilson Chronic hypersecretion of luteinizing hormone in transgenic mice selectively alters responsiveness of the α-subunit gene to gonadotropin-releasing hormone and estrogens Mol. Endocrinol. 13 1999 1449 1459
    • (1999) Mol. Endocrinol. , vol.13 , pp. 1449-1459
    • Abbud, R.A.1    Ameduri, R.K.2    Rao, J.S.3    Nett, T.M.4    Nilson, J.H.5
  • 2
    • 0019987249 scopus 로고
    • Prolactin cells in the human pituitary. A quantitative immunocytochemical analysis
    • S.L. Asa, G. Penz, K. Kovacs, and C. Ezrin Prolactin cells in the human pituitary. A quantitative immunocytochemical analysis Arch. Pathol. Lab. Med. 106 1982 360 363
    • (1982) Arch. Pathol. Lab. Med. , vol.106 , pp. 360-363
    • Asa, S.L.1    Penz, G.2    Kovacs, K.3    Ezrin, C.4
  • 3
    • 0036320874 scopus 로고    scopus 로고
    • Minireview: Genetic models for the study of gonadotropin actions
    • K.H. Burns, and M.M. Matzuk Minireview: genetic models for the study of gonadotropin actions Endocrinology 143 2002 2823 2835
    • (2002) Endocrinology , vol.143 , pp. 2823-2835
    • Burns, K.H.1    Matzuk, M.M.2
  • 5
    • 0018828995 scopus 로고
    • Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin
    • A.K. Christensen, and K.C. Peacock Increase in Leydig cell number in testes of adult rats treated chronically with an excess of human chorionic gonadotropin Biol. Reprod. 22 1980 383 391
    • (1980) Biol. Reprod. , vol.22 , pp. 383-391
    • Christensen, A.K.1    Peacock, K.C.2
  • 6
    • 0030999939 scopus 로고    scopus 로고
    • Leydig cell hyperplasia and adenoma formation: Mechanisms and relevance to humans
    • E.D. Clegg, J.C. Cook, R.E. Chapin, P.M. Foster, and G.P. Daston Leydig cell hyperplasia and adenoma formation: mechanisms and relevance to humans Reprod. Toxicol. 11 1997 107 121
    • (1997) Reprod. Toxicol. , vol.11 , pp. 107-121
    • Clegg, E.D.1    Cook, J.C.2    Chapin, R.E.3    Foster, P.M.4    Daston, G.P.5
  • 8
    • 0028318585 scopus 로고
    • Mature cystic teratoma: A clinicopathologic evaluation of 517 cases and review of the literature
    • J.T. Comerci Jr., F. Licciardi, P.A. Bergh, C. Gregori, and J.L. Breen Mature cystic teratoma: a clinicopathologic evaluation of 517 cases and review of the literature Obstet. Gynecol. 84 1994 22 28
    • (1994) Obstet. Gynecol. , vol.84 , pp. 22-28
    • Comerci Jr., J.T.1    Licciardi, F.2    Bergh, P.A.3    Gregori, C.4    Breen, J.L.5
  • 9
    • 0032524950 scopus 로고    scopus 로고
    • Coexpression of gonadotropic hormones and their corresponding FSH- and LH/CG-receptors in the human prostate
    • S. Dirnhofer, C. Berger, M. Hermann, G. Steiner, S. Madersbacher, and P. Berger Coexpression of gonadotropic hormones and their corresponding FSH- and LH/CG-receptors in the human prostate Prostate 35 1998 212 220
    • (1998) Prostate , vol.35 , pp. 212-220
    • Dirnhofer, S.1    Berger, C.2    Hermann, M.3    Steiner, G.4    Madersbacher, S.5    Berger, P.6
  • 10
    • 0033771336 scopus 로고    scopus 로고
    • Prolactin: Structure, function, and regulation of secretion
    • M.E. Freeman, B. Kanyicska, A. Lerant, and G. Nagy Prolactin: structure, function, and regulation of secretion Physiol. Rev. 80 2000 1523 1631
    • (2000) Physiol. Rev. , vol.80 , pp. 1523-1631
    • Freeman, M.E.1    Kanyicska, B.2    Lerant, A.3    Nagy, G.4
  • 11
    • 0035919207 scopus 로고    scopus 로고
    • Origin, differentiation and regulation of fetal and adult Leydig cells
    • R. Habert, H. Lejeune, and J.M. Saez Origin, differentiation and regulation of fetal and adult Leydig cells Mol. Cell Endocrinol. 179 2001 47 74
    • (2001) Mol. Cell Endocrinol. , vol.179 , pp. 47-74
    • Habert, R.1    Lejeune, H.2    Saez, J.M.3
  • 12
    • 0032742157 scopus 로고    scopus 로고
    • Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis
    • A.P. Heaney, G.A. Horwitz, Z. Wang, R. Singson, and S. Melmed Early involvement of estrogen-induced pituitary tumor transforming gene and fibroblast growth factor expression in prolactinoma pathogenesis Nat. Med. 5 1999 1317 1321
    • (1999) Nat. Med. , vol.5 , pp. 1317-1321
    • Heaney, A.P.1    Horwitz, G.A.2    Wang, Z.3    Singson, R.4    Melmed, S.5
  • 13
    • 0032992951 scopus 로고    scopus 로고
    • Determinants of transcription of the chorionic gonadotropin/luteinizing hormone receptor gene in human breast cells
    • Y.L. Hu, Z.M. Lei, Z.H. Huang, and C.V. Rao Determinants of transcription of the chorionic gonadotropin/luteinizing hormone receptor gene in human breast cells Breast J. 5 1999 186 193
    • (1999) Breast J. , vol.5 , pp. 186-193
    • Hu, Y.L.1    Lei, Z.M.2    Huang, Z.H.3    Rao, C.V.4
  • 14
    • 0028850093 scopus 로고
    • Immortalized anterior pituitary alpha T3 gonadotropes contain functional luteinizing hormone/human chorionic gonadotropin receptors
    • Z.H. Huang, Z.M. Lei, and C.V. Rao Immortalized anterior pituitary alpha T3 gonadotropes contain functional luteinizing hormone/human chorionic gonadotropin receptors Mol. Cell. Endocrinol. 114 1995 217 222
    • (1995) Mol. Cell. Endocrinol. , vol.114 , pp. 217-222
    • Huang, Z.H.1    Lei, Z.M.2    Rao, C.V.3
  • 15
    • 0030787593 scopus 로고    scopus 로고
    • Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene
    • K. Kananen, Rilianawati, T. Paukku, M. Markkula, E.M. Rainio, and I. Huhtanemi Suppression of gonadotropins inhibits gonadal tumorigenesis in mice transgenic for the mouse inhibin alpha-subunit promoter/simian virus 40 T-antigen fusion gene Endocrinology 138 1997 3521 3531
    • (1997) Endocrinology , vol.138 , pp. 3521-3531
    • Kananen, K.1    Rilianawati2    Paukku, T.3    Markkula, M.4    Rainio, E.M.5    Huhtanemi, I.6
  • 16
  • 17
    • 0034602808 scopus 로고    scopus 로고
    • Luteinizing hormone induction of ovarian tumors: Oligogenic differences between mouse strains dictates tumor disposition
    • R.A. Keri, K.L. Lozada, F.W. Abdul-Karim, J.N. Nadeau, and J.H. Nilson Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition Proc. Natl. Acad. Sci. U.S.A. 97 2000 383 387
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 383-387
    • Keri, R.A.1    Lozada, K.L.2    Abdul-Karim, F.W.3    Nadeau, J.N.4    Nilson, J.H.5
  • 19
    • 0032742479 scopus 로고    scopus 로고
    • Review: Gonadotropins and development of ovarian cancer
    • I. Konishi, H. Kuroda, and M. Mandai Review: gonadotropins and development of ovarian cancer Oncology 57 Suppl. 2 1999 45 48
    • (1999) Oncology , vol.57 , Issue.2 SUPPL. , pp. 45-48
    • Konishi, I.1    Kuroda, H.2    Mandai, M.3
  • 20
    • 0033304622 scopus 로고    scopus 로고
    • Transgenic models to study gonadotropin function: The role of follicle-stimulating hormone in gonadal growth and tumorigenesis
    • T.R. Kumar, G. Palapattu, P. Wang, T.K. Woodruff, I. Boime, M.C. Byrne, and M.M. Matzuk Transgenic models to study gonadotropin function: the role of follicle-stimulating hormone in gonadal growth and tumorigenesis Mol. Endocrinol. 13 1999 851 865
    • (1999) Mol. Endocrinol. , vol.13 , pp. 851-865
    • Kumar, T.R.1    Palapattu, G.2    Wang, P.3    Woodruff, T.K.4    Boime, I.5    Byrne, M.C.6    Matzuk, M.M.7
  • 21
    • 0031054284 scopus 로고    scopus 로고
    • Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility
    • T.R. Kumar, Y. Wang, N. Lu, and M.M. Matzuk Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility Nat. Genet. 15 1997 201 204
    • (1997) Nat. Genet. , vol.15 , pp. 201-204
    • Kumar, T.R.1    Wang, Y.2    Lu, N.3    Matzuk, M.M.4
  • 22
    • 0029742472 scopus 로고    scopus 로고
    • Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice
    • T.R. Kumar, Y. Wang, and M.M. Matzuk Gonadotropins are essential modifier factors for gonadal tumor development in inhibin-deficient mice Endocrinology 137 1996 4210 4216
    • (1996) Endocrinology , vol.137 , pp. 4210-4216
    • Kumar, T.R.1    Wang, Y.2    Matzuk, M.M.3
  • 23
    • 0026760102 scopus 로고
    • The expression of human chorionic gonadotropin/luteinizing hormone receptors in human endometrial and myometrial blood vessels
    • Z.M. Lei, E. Reshef, and V. Rao The expression of human chorionic gonadotropin/luteinizing hormone receptors in human endometrial and myometrial blood vessels J. Clin. Endocrinol. Metab. 75 1992 651 659
    • (1992) J. Clin. Endocrinol. Metab. , vol.75 , pp. 651-659
    • Lei, Z.M.1    Reshef, E.2    Rao, V.3
  • 24
    • 0035001669 scopus 로고    scopus 로고
    • On the role of human chorionic gonadotropin (hCG) in the embryo-endometrial microenvironment: Implications for differentiation and implantation
    • P. Licht, V. Russu, and L. Wildt On the role of human chorionic gonadotropin (hCG) in the embryo-endometrial microenvironment: implications for differentiation and implantation Semin. Reprod. Med. 19 2001 37 47
    • (2001) Semin. Reprod. Med. , vol.19 , pp. 37-47
    • Licht, P.1    Russu, V.2    Wildt, L.3
  • 25
    • 0033518280 scopus 로고    scopus 로고
    • Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor
    • G. Liu, L. Duranteau, J.C. Carel, J. Monroe, D.A. Doyle, and A. Shenker Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor N. Engl. J. Med. 341 1999 1731 1736
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1731-1736
    • Liu, G.1    Duranteau, L.2    Carel, J.C.3    Monroe, J.4    Doyle, D.A.5    Shenker, A.6
  • 26
    • 0033279007 scopus 로고    scopus 로고
    • Transgenic mice with chronically elevated luteinizing hormone are infertile due to anovulation, defects in uterine receptivity, and midgestation pregnancy failure
    • R.J. Mann, R.A. Keri, and J.H. Nilson Transgenic mice with chronically elevated luteinizing hormone are infertile due to anovulation, defects in uterine receptivity, and midgestation pregnancy failure Endocrinology 140 1999 2592 2601
    • (1999) Endocrinology , vol.140 , pp. 2592-2601
    • Mann, R.J.1    Keri, R.A.2    Nilson, J.H.3
  • 27
    • 0028848396 scopus 로고
    • The follicle-stimulating hormone (FSH) beta- and common alpha-subunits are expressed in mouse testis, as determined in wild-type mice and those transgenic for the FSH beta-subunit/herpes simplex virus thymidine kinase fusion gene
    • M. Markkula, T. Hämäläinen, E. Loune, and I. Huhtaniemi The follicle-stimulating hormone (FSH) beta- and common alpha-subunits are expressed in mouse testis, as determined in wild-type mice and those transgenic for the FSH beta-subunit/herpes simplex virus thymidine kinase fusion gene Endocrinology 136 1995 4769 4775
    • (1995) Endocrinology , vol.136 , pp. 4769-4775
    • Markkula, M.1    Hämäläinen, T.2    Loune, E.3    Huhtaniemi, I.4
  • 28
    • 0038112173 scopus 로고    scopus 로고
    • Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice
    • M.M. Matzuk, F.J. DeMayo, L.A. Hadsell, and T.R. Kumar Overexpression of human chorionic gonadotropin causes multiple reproductive defects in transgenic mice Biol. Reprod. 69 2003 338 346
    • (2003) Biol. Reprod. , vol.69 , pp. 338-346
    • Matzuk, M.M.1    Demayo, F.J.2    Hadsell, L.A.3    Kumar, T.R.4
  • 29
    • 0037378475 scopus 로고    scopus 로고
    • Luteinizing hormone receptor status and clinical, pathologic, and prognostic features in patients with breast carcinomas
    • G. Meduri, N. Charnaux, F. Spyratos, K. Hacene, H. Loosfelt, and E. Milgrom Luteinizing hormone receptor status and clinical, pathologic, and prognostic features in patients with breast carcinomas Cancer 97 2003 1810 1816
    • (2003) Cancer , vol.97 , pp. 1810-1816
    • Meduri, G.1    Charnaux, N.2    Spyratos, F.3    Hacene, K.4    Loosfelt, H.5    Milgrom, E.6
  • 30
    • 0038621388 scopus 로고    scopus 로고
    • High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-alpha-subunit promoter/Simian virus 40 T-antigen fusion gene
    • M. Mikola, J. Kero, J.H. Nilson, R.A. Keri, M. Poutanen, and I. Huhtaniemi High levels of luteinizing hormone analog stimulate gonadal and adrenal tumorigenesis in mice transgenic for the mouse inhibin-alpha-subunit promoter/Simian virus 40 T-antigen fusion gene Oncogene 22 2003 3269 3278
    • (2003) Oncogene , vol.22 , pp. 3269-3278
    • Mikola, M.1    Kero, J.2    Nilson, J.H.3    Keri, R.A.4    Poutanen, M.5    Huhtaniemi, I.6
  • 31
    • 0141562048 scopus 로고    scopus 로고
    • Targeted overexpression of luteinizing hormone causes ovary-dependent functional adenomas restricted to cells of the Pit-1 lineage
    • H.P. Mohammad, R.A. Abbud, A.F. Parlow, J.S. Lewin, and J.H. Nilson Targeted overexpression of luteinizing hormone causes ovary-dependent functional adenomas restricted to cells of the Pit-1 lineage Endocrinology 144 2003 4626 4636
    • (2003) Endocrinology , vol.144 , pp. 4626-4636
    • Mohammad, H.P.1    Abbud, R.A.2    Parlow, A.F.3    Lewin, J.S.4    Nilson, J.H.5
  • 32
    • 0023447946 scopus 로고
    • Teratoma genetics and stem cells: A review
    • G.L. Mutter Teratoma genetics and stem cells: a review Obstet. Gynecol. Surv. 42 1987 661 670
    • (1987) Obstet. Gynecol. Surv. , vol.42 , pp. 661-670
    • Mutter, G.L.1
  • 33
    • 0031565929 scopus 로고    scopus 로고
    • Role of imprinting in abnormal human development
    • G.L. Mutter Role of imprinting in abnormal human development Mutat. Res. 396 1997 141 147
    • (1997) Mutat. Res. , vol.396 , pp. 141-147
    • Mutter, G.L.1
  • 34
    • 0036712830 scopus 로고    scopus 로고
    • Failure of normal adult Leydig cell development in androgen-receptor- deficient mice
    • P.J. O'Shaughnessy, H. Johnston, L. Willerton, and P.J. Baker Failure of normal adult Leydig cell development in androgen-receptor-deficient mice J. Cell Sci. 115 2002 3491 3496
    • (2002) J. Cell Sci. , vol.115 , pp. 3491-3496
    • O'Shaughnessy, P.J.1    Johnston, H.2    Willerton, L.3    Baker, P.J.4
  • 35
    • 0036195674 scopus 로고    scopus 로고
    • Changes in Leydig cell gene expression during development in the mouse
    • P.J. O'Shaughnessy, L. Willerton, and P.J. Baker Changes in Leydig cell gene expression during development in the mouse Biol. Reprod. 66 2002 966 975
    • (2002) Biol. Reprod. , vol.66 , pp. 966-975
    • O'Shaughnessy, P.J.1    Willerton, L.2    Baker, P.J.3
  • 36
    • 85047681722 scopus 로고    scopus 로고
    • Ovulatory surges of hCG prevent hormone-induced granulosa cell tumor formation leading to the identification of tumor-associated changes in the transcriptome
    • G.E. Owens, R.A. Keri, and J.H. Nilson Ovulatory surges of hCG prevent hormone-induced granulosa cell tumor formation leading to the identification of tumor-associated changes in the transcriptome Mol. Endocrinol. 16 2002 1230 1242
    • (2002) Mol. Endocrinol. , vol.16 , pp. 1230-1242
    • Owens, G.E.1    Keri, R.A.2    Nilson, J.H.3
  • 38
    • 0035013450 scopus 로고    scopus 로고
    • An overview of the past, present, and future of nongonadal LH/hCG actions in reproductive biology and medicine
    • C.V. Rao An overview of the past, present, and future of nongonadal LH/hCG actions in reproductive biology and medicine Semin. Reprod. Med. 19 2001 7 17
    • (2001) Semin. Reprod. Med. , vol.19 , pp. 7-17
    • Rao, C.V.1
  • 39
    • 2942627184 scopus 로고    scopus 로고
    • Human chorionic gonadotropin decreases proliferation and invasion of breast cancer MCF-7 cells by inhibiting NF-kappaB and AP-1 activation
    • Ch.V. Rao, X. Li, S.K. Manna, Z.M. Lei, and B.B. Aggarwal Human chorionic gonadotropin decreases proliferation and invasion of breast cancer MCF-7 cells by inhibiting NF-kappaB and AP-1 activation J. Biol. Chem. 279 2004 25503 25510
    • (2004) J. Biol. Chem. , vol.279 , pp. 25503-25510
    • Rao, Ch.V.1    Li, X.2    Manna, S.K.3    Lei, Z.M.4    Aggarwal, B.B.5
  • 40
    • 0028798786 scopus 로고
    • Expression and functionality of luteinizing hormone/chorionic gonadotropin receptor in the rat prostate
    • E. Reiter, M. McNamara, J. Closset, and G. Hennen Expression and functionality of luteinizing hormone/chorionic gonadotropin receptor in the rat prostate Endocrinology 136 1995 917 923
    • (1995) Endocrinology , vol.136 , pp. 917-923
    • Reiter, E.1    McNamara, M.2    Closset, J.3    Hennen, G.4
  • 41
    • 0028923296 scopus 로고
    • Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors
    • K.A. Risma, C.M. Clay, T.M. Nett, T. Wagner, J. Yun, and J.H. Nilson Targeted overexpression of luteinizing hormone in transgenic mice leads to infertility, polycystic ovaries, and ovarian tumors Proc. Natl. Acad. Sci. U.S.A. 92 1995 1322 1326
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 1322-1326
    • Risma, K.A.1    Clay, C.M.2    Nett, T.M.3    Wagner, T.4    Yun, J.5    Nilson, J.H.6
  • 42
    • 0030741673 scopus 로고    scopus 로고
    • Elevated luteinizing hormone in prepubertal transgenic mice causes hyperandrogenemia, precocious puberty, and substantial ovarian pathology
    • K.A. Risma, A.N. Hirshfield, and J.H. Nilson Elevated luteinizing hormone in prepubertal transgenic mice causes hyperandrogenemia, precocious puberty, and substantial ovarian pathology Endocrinology 138 1997 3540 3547
    • (1997) Endocrinology , vol.138 , pp. 3540-3547
    • Risma, K.A.1    Hirshfield, A.N.2    Nilson, J.H.3
  • 43
    • 0242552024 scopus 로고    scopus 로고
    • Elevated steroidogenesis, defective reproductive organs, and infertility in transgenic male mice overexpressing human chorionic gonadotropin
    • S.B. Rulli, P. Ahtiainen, S. Makela, J. Toppari, M. Poutanen, and I. Huhtaniemi Elevated steroidogenesis, defective reproductive organs, and infertility in transgenic male mice overexpressing human chorionic gonadotropin Endocrinology 144 2003 4980 4990
    • (2003) Endocrinology , vol.144 , pp. 4980-4990
    • Rulli, S.B.1    Ahtiainen, P.2    Makela, S.3    Toppari, J.4    Poutanen, M.5    Huhtaniemi, I.6
  • 44
    • 0036772574 scopus 로고    scopus 로고
    • Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin
    • S.B. Rulli, A.I. Kuorelahti, O. Karaer, L. Pelliniemi, M. Poutanen, and I.T. Huhtaniemi Reproductive disturbances, pituitary lactotrope adenomas, and mammary gland tumors in transgenic female mice producing high levels of human chorionic gonadotropin Endocrinology 143 2002 4084 4095
    • (2002) Endocrinology , vol.143 , pp. 4084-4095
    • Rulli, S.B.1    Kuorelahti, A.I.2    Karaer, O.3    Pelliniemi, L.4    Poutanen, M.5    Huhtaniemi, I.T.6
  • 45
    • 0025239266 scopus 로고
    • The pituitary gland in pregnancy: A clinicopathologic and immunohistochemical study of 69 cases
    • B.W. Scheithauer, T. Sano, K.T. Kovacs, W.F. Young, N. Ryan, and R.V. Randall The pituitary gland in pregnancy: a clinicopathologic and immunohistochemical study of 69 cases Mayo Clin. Proc. 65 1990 461 474
    • (1990) Mayo Clin. Proc. , vol.65 , pp. 461-474
    • Scheithauer, B.W.1    Sano, T.2    Kovacs, K.T.3    Young, W.F.4    Ryan, N.5    Randall, R.V.6
  • 47
    • 0035015965 scopus 로고    scopus 로고
    • Functional importance of bovine myometrial and vascular LH receptors and cervical FSH receptors
    • M. Shemesh, D. Mizrachi, M. Gurevich, Y. Stram, L.S. Shore, and M.J. Fields Functional importance of bovine myometrial and vascular LH receptors and cervical FSH receptors Semin. Reprod. Med. 19 2001 87 96
    • (2001) Semin. Reprod. Med. , vol.19 , pp. 87-96
    • Shemesh, M.1    Mizrachi, D.2    Gurevich, M.3    Stram, Y.4    Shore, L.S.5    Fields, M.J.6
  • 48
    • 0032512612 scopus 로고    scopus 로고
    • Estrogen-induced tumorigenesis in the Copenhagen rat: Disparate susceptibilities to development of prolactin-producing pituitary tumors and mammary carcinomas
    • T.J. Spady, D. Harvell, M.C. Snyder, K.L. Pennington, R.D. McComb, and J.D. Shull Estrogen-induced tumorigenesis in the Copenhagen rat: disparate susceptibilities to development of prolactin-producing pituitary tumors and mammary carcinomas Cancer Lett. 124 1998 95 103
    • (1998) Cancer Lett. , vol.124 , pp. 95-103
    • Spady, T.J.1    Harvell, D.2    Snyder, M.C.3    Pennington, K.L.4    McComb, R.D.5    Shull, J.D.6
  • 50
    • 0031779388 scopus 로고    scopus 로고
    • Seminal vesicles are novel sites of luteinizing hormone/human chorionic gonadotropin-receptor gene expression
    • Y.X. Tao, Z.M. Lei, and C.V. Rao Seminal vesicles are novel sites of luteinizing hormone/human chorionic gonadotropin-receptor gene expression J. Androl. 19 1998 343 347
    • (1998) J. Androl. , vol.19 , pp. 343-347
    • Tao, Y.X.1    Lei, Z.M.2    Rao, C.V.3
  • 51
    • 1842376911 scopus 로고    scopus 로고
    • Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility
    • J.S. Tapanainen, K. Aittomäki, J. Min, T. Vaskivuo, and I.T. Huhtaniemi Men homozygous for an inactivating mutation of the follicle-stimulating hormone (FSH) receptor gene present variable suppression of spermatogenesis and fertility Nat. Genet. 15 1997 205 206
    • (1997) Nat. Genet. , vol.15 , pp. 205-206
    • Tapanainen, J.S.1    Aittomäki, K.2    Min, J.3    Vaskivuo, T.4    Huhtaniemi, I.T.5
  • 52
    • 0033711033 scopus 로고    scopus 로고
    • Mutations of gonadotropins and gonadotropin receptors: Elucidating the physiology and pathophysiology of pituitary-gonadal function
    • A.P.N. Themmen, and I.T. Huhtaniemi Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function Endocrinol. Rev. 21 2000 551 583
    • (2000) Endocrinol. Rev. , vol.21 , pp. 551-583
    • Themmen, A.P.N.1    Huhtaniemi, I.T.2
  • 53
    • 3142707560 scopus 로고    scopus 로고
    • Gonadal teratomas: A review and speculation
    • T.M. Ulbright Gonadal teratomas: a review and speculation Adv. Anat. Pathol. 11 2004 10 23
    • (2004) Adv. Anat. Pathol. , vol.11 , pp. 10-23
    • Ulbright, T.M.1
  • 56
    • 0344823859 scopus 로고    scopus 로고
    • The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis
    • F.P. Zhang, T. Pakarainen, M. Poutanen, J. Toppari, and I. Huhtaniemi The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis Proc. Natl. Acad. Sci. U.S.A. 100 2003 13692 13697
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 13692-13697
    • Zhang, F.P.1    Pakarainen, T.2    Poutanen, M.3    Toppari, J.4    Huhtaniemi, I.5
  • 57
    • 0022444734 scopus 로고
    • Evidence for the presence of luteinizing hormone/human chorionic gonadotropin-binding sites in the porcine uterus
    • A.J. Ziecik, P.D. Stanchev, and J.E. Tilton Evidence for the presence of luteinizing hormone/human chorionic gonadotropin-binding sites in the porcine uterus Endocrinology 119 1986 1159 1163
    • (1986) Endocrinology , vol.119 , pp. 1159-1163
    • Ziecik, A.J.1    Stanchev, P.D.2    Tilton, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.