Cortical excitability during prolonged antiepileptic drug treatment and drug withdrawal

Clinical Neurophysiology

Volumn 116, Issue 5, 2005, Pages 1105-1112

  Lee, H W ^a,b   Seo, H J ^a   Cohen, L G ^a   Bagic, A ^a   Theodore, W H ^a  

^a National Institute of Neurological Disorders   (United States)

^b Ewha Womans University School of Medicine   (South Korea)

Author keywords

Antiepileptic drug treatment; Cortical excitability; Drug withdrawal; Plasma blood levels; Transcranial magnetic stimulation

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; LAMOTRIGINE;

ADULT; ANALYSIS OF VARIANCE; CENTRAL NERVOUS SYSTEM DISEASE; CONFERENCE PAPER; CONTROLLED STUDY; DATA ANALYSIS; DRUG BLOOD LEVEL; DRUG ERUPTION; DRUG HALF LIFE; DRUG WITHDRAWAL; HUMAN; MOTOR CORTEX; NORMAL HUMAN; PRIORITY JOURNAL; REGRESSION ANALYSIS; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 17044378543     PISSN: 13882457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinph.2004.12.004     Document Type: Conference Paper

References (46)

1. A.T. Beck, C.H. Ward, M. Mendelson, J. Mock, and J. Erbaugh An inventory for measuring depression Arch Gen Psychiatry 4 1961 561 571
2. B. Boroojerdi, F. Battaglia, W. Muellbacher, and L.G. Cohen Mechanisms influencing stimulus-response properties of the human corticospinal system Clin Neurophysiol 112 2001 931 937
3. M.F. Braga, V. Aroniadou-Anderjaska, R.M. Post, and H. Li Lamotrigine reduces spontaneous and evoked GABAA receptor-mediated synaptic transmission in the basolateral amygdala: implications for its effects in seizure and affective disorders Neuropharmacology 42 2002 522 529
4. J.P. Brasil-Neto, L.G. Cohen, M. Panizza, J. Nilsson, B.J. Roth, and M. Hallett Optimal focal transcranial magnetic activation of the human motor cortex: effects of coil orientation, shape of the induced current pulse, and stimulus intensity J Clin Neurophysiol 9 1992 132 136
5. R. Chen, A. Samii, M. Canos, E.M. Wassermann, and M. Hallett Effects of phenytoin on cortical excitability in humans Neurology 49 1997 881 883
6. R. Chen, A. Tam, C. Butefisch, B. Corwell, U. Ziemann, J.C. Rothwell, and L.G. Cohen Intracortical inhibition and facilitation in different representations of the human motor cortex J Neurophysiol 80 1998 2870 2881
7. H. Devanne, B.A. Lavoie, and C. Capaday Input-output properties and gain changes in the human corticospinal pathway Exp Brain Res 114 1997 329 338
8. V. Di Lazzaro, A. Oliviero, M. Meglio, B. Cioni, G. Tamburrini, P. Tonali, and J.C. Rothwell Direct demonstration of the effect of lorazepam on the excitability of the human motor cortex Clin Neurophysiol 111 2000 794 799
9. J.S. Duncan, S.D. Shorvon, and M.R. Trimble Withdrawal symptoms from phenytoin, carbamazepine and sodium valproate J Neurol Neurosurg Psychiatry 51 1988 924 928
10. J.L. Fernandez-Torre De novo absence status of late onset following withdrawal of lorazepam: a case report Seizure 10 2001 433 437
11. A. Goldlust, T.Z. Su, D.F. Welty, C.P. Taylor, and D.L. Oxender Effects of anticonvulsant drug gabapentin on the enzymes in metabolic pathways of glutamate and GABA Epilepsy Res 22 1995 1 11
12. M.E. Hasselmo Neuromodulation and cortical function: modeling the physiological basis of behavior Behav Brain Res 67 1995 1 27
13. T.V. Ilic, F. Meintzschel, U. Cleff, D. Ruge, K.R. Kessler, and U. Ziemann Short-interval paired-pulse inhibition and facilitation of human motor cortex: the dimension of stimulus intensity J Physiol 545 2002 153 167
14. M. Inghilleri, A. Conte, V. Frasca, A. Curra, F. Gilio, M. Manfredi, and A. Berardelli Antiepileptic drugs and cortical excitability: a study with repetitive transcranial stimulation Exp Brain Res 154 2004 488 493
15. T.A. Ketter, B.A. Malow, R. Flamini, S.R. White, R.M. Post, and W.H. Theodore Anticonvulsant withdrawal-emergent psychopathology Neurology 44 1994 55 61
16. T. Kujirai, M.D. Caramia, J.C. Rothwell, B.L. Day, P.D. Thompson, A. Ferbert, S. Wroe, P. Asselman, and C.D. Marsden Corticocortical inhibition in human motor cortex J Physiol 471 1993 501 519
17. R. Kuzniecky, S. Ho, J. Pan, R. Martin, F. Gilliam, E. Faught, and H. Hetherington Modulation of cerebral GABA by topiramate, lamotrigine, and gabapentin in healthy adults Neurology 58 2002 368 372
18. P. Kwan, G.J. Sills, and M.J. Brodie The mechanisms of action of commonly used antiepileptic drugs Pharmacol Ther 90 2001 21 34
19. H. Lampe, and H. Bigalke Carbamazepine blocks NMDA-activated currents in cultured spinal cord neurons Neuroreport 1 1990 26 28
20. M.J. Leach, G. Lees, and D.R. Riddall Lamotrigine: mechanisms of action R.H. Levy R.H. Mattson B.S. Meldrum Antiepileptic Drugs 1995 Raven Press, Ltd New York, NY 861 869
21. G. Lees, and M.J. Leach Studies on the mechanism of action of the novel anticonvulsant lamotrigine (Lamictal) using primary neurological cultures from rat cortex Brain Res 612 1993 190 199
22. R.L. Macdonald Carbamazepine: mechanisms of action R.H. Levy R.H. Mattson B.S. Meldrum Antiepileptic Drugs 1995 Raven Press, Ltd New York, NY 491 498
23. B.A. Malow, T.A. Blaxton, B. Stertz, and W.H. Theodore Carbamazepine withdrawal: effects of taper rate on seizure frequency Neurology 43 1993 2280 2284
24. P. Manganotti, L.G. Bongiovanni, G. Zanette, M. Turazzini, and A. Fiaschi Cortical excitability in patients after loading doses of lamotrigine: a study with magnetic brain stimulation Epilepsia 40 1999 316 321
25. M.G. Marciani, J. Gotman, F. Andermann, and A. Olivier Patterns of seizure activation after withdrawal of antiepileptic medication Neurology 35 1985 1537 1543
26. D.A. Marks, A. Katz, R. Scheyer, and S.S. Spencer Clinical and electrographic effects of acute anticonvulsant withdrawal in epileptic patients Neurology 41 1991 508 512
27. N. Mavroudakis, J.M. Caroyer, E. Brunko, and D. Zegers de Beyl Effects of diphenylhydantoin on motor potentials evoked with magnetic stimulation Electroencephalogr Clin Neurophysiol 93 1994 428 433
28. M.J. McLean, and R.L. Macdonald Carbamazepine and 10,11- epoxycarbamazepine produce use- and voltage-dependent limitation of rapidly firing action potentials of mouse central neurons in cell culture J Pharmacol Exp Ther 238 1986 727 738
29. A.A. Miller, P. Wheatley, D.A. Sawyer, M.G. Baxter, and B. Roth Pharmacological studies on lamotrigine, a novel potential antiepileptic drug: I. Anticonvulsant profile in mice and rats Epilepsia 27 1986 483 489
30. O.A. Petroff, D.L. Rothman, K.L. Behar, D. Lamoureux, and R.H. Mattson The effect of gabapentin on brain gamma-aminobutyric acid in patients with epilepsy Ann Neurol 39 1996 95 99
31. V. Rizzo, A. Quartarone, S. Bagnato, F. Battaglia, G. Majorana, and P. Girlanda Modification of cortical excitability induced by gabapentin: a study by transcranial magnetic stimulation Neurol Sci 22 2001 229 232
32. J.D. Rollnik, S. Siggelkow, J. Dauper, R. Dengler, and A. Kossev Effect of conditioning transcranial stimulation on motor evoked potentials Acta Physiol Pharmacol Bulg 26 2001 123 125
33. P. Schwenkreis, J. Liepert, K. Witscher, W. Fischer, C. Weiller, J.P. Malin, and M. Tegenthoff Riluzole suppresses motor cortex facilitation in correlation to its plasma level. A study using transcranial magnetic stimulation Exp Brain Res 135 2000 293 299
34. I.S. Shiah, L.N. Yatham, Y.C. Gau, and G.B. Baker Effect of lamotrigine on plasma GABA levels in healthy humans Prog Neuropsychopharmacol Biol Psychiatry 27 2003 419 423
35. V.A. Sironi, A. Franzini, L. Ravagnati, and F. Marossero Interictal acute psychoses in temporal lobe epilepsy during withdrawal of anticonvulsant therapy J Neurol Neurosurg Psychiatry 42 1979 724 730
36. N. So, and J. Gotman Changes in seizure activity following anticonvulsant drug withdrawal Neurology 40 1990 407 413
37. 2+ currents in cortical neurons: functional implications Eur J Pharmacol 307 1996 113 116
38. A. Stefani, F. Spadoni, and G. Bernardi Gabapentin inhibits calcium currents in isolated rat brain neurons Neuropharmacology 37 1998 83 91
39. F. Tergau, S. Wischer, H.S. Somal, M.A. Nitsche, A.J. Joe Mercer, W. Paulus, and B.J. Steinhoff Relationship between lamotrigine oral dose, serum level and its inhibitory effect on CNS: insights from transcranial magnetic stimulation Epilepsy Res 56 2003 67 77
40. W.H. Theodore, R.J. Porter, and R.F. Raubertas Seizures during barbiturate withdrawal: relation to blood level Ann Neurol 22 1987 644 647
41. M. Turazzini, P. Manganotti, R. Del Colle, M. Silvestri, and A. Fiaschi Serum levels of carbamazepine and cortical excitability by magnetic brain stimulation Neurol Sci 25 2004 83 90
42. ++ influx in dissociated amygdala neurons Synapse 29 1998 355 362
43. J.F. Wang, X. Sun, B. Chen, and L.T. Young Lamotrigine increases gene expression of GABA-A receptor beta3 subunit in primary cultured rat hippocampus cells Neuropsychopharmacology 26 2002 415 421
44. U. Ziemann, S. Lonnecker, B.J. Steinhoff, and W. Paulus Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study Ann Neurol 40 1996 367 378
45. U. Ziemann, F. Tergau, S. Wischer, J. Hildebrandt, and W. Paulus Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study Electroencephalogr Clin Neurophysiol 109 1998 321 330
46. U. Ziemann, R. Chen, L.G. Cohen, and M. Hallett Dextromethorphan decreases the excitability of the human motor cortex Neurology 51 1998 1320 1324