Relationship between lamotrigine oral dose, serum level and its inhibitory effect on CNS: Insights from transcranial magnetic stimulation

Epilepsy Research

Volumn 56, Issue 1, 2003, Pages 67-77

  Tergau, Frithjof ^a   Wischer, Stephan ^a   Somal, Hardyal S ^b   Nitsche, Michael A ^a   Mercer, A Joe ^b   Paulus, Walter ^a   Steinhoff, Bernhard J ^a,c  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Epilepsiezentrum Kork   (Germany)

Author keywords

Cortex excitability; Dose response relationship; Drug resistance; Epilepsy; Human; Motor threshold; Sodium channel blocker

Indexed keywords

LAMOTRIGINE; PLACEBO; SODIUM CHANNEL BLOCKING AGENT;

ADULT; ARTICLE; CENTRAL NERVOUS SYSTEM; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG MECHANISM; HUMAN; HUMAN EXPERIMENT; LINEAR SYSTEM; MALE; NERVE EXCITABILITY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 0141755367     PISSN: 09201211     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eplepsyres.2003.08.006     Document Type: Article

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