Synthesis and in vitro and in vivo evaluation of three radioiodinated nitroimidazole analogues as tumor hypoxia markers

Nuclear Medicine and Biology

Volumn 32, Issue 3, 2005, Pages 225-231

  Li, Zejun ^a   Chu, Taiwei ^a   Liu, Xinqi ^a   Wang, Xiangyun ^a  

^a PEKING UNIVERSITY   (China)

Author keywords

Biodistribution; Hypoxia; Iodine 131; Nitroimidazole; Tumor

Indexed keywords

ARABINOSIDE; BRU 59 21; BRU 59 21 TC 99M; FLUOROMISONIDAZOLE H 3; IMIDAZOLE DERIVATIVE; IODINE 125; IODINE 131; IODOAZOMYCIN ARABINOSIDE I 125; MISONIDAZOLE; MISONIDAZOLE H 3; N [4 (BENZOTHIAZOL 2 YL)PHENYL] 3 (2 NITROIMIDAZOL 1 YL)PROPANAMIDE I 131; N [4 (BENZOTHIAZOL 2 YL)PHENYL] 3 (4 NITROIMIDAZOL 1 YL) N METHYLPROPANAMIDE I 131; N [4 (BENZOTHIAZOL 2 YL)PHENYL] 3 (4 NITROIMIDAZOL 1 YL)PROPANAMIDE I 131; NITROIMIDAZOLE DERIVATIVE; OXO[3,3,9,9 TETRAMETHYL 1 (2 NITRO 1H IMIDAZOL 1 YL) 4,8 DIAZAUNDECANE 2,10 DIONEDIOXIMATO]TECHNETIUM TC 99M; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG; UPENAZIME; UPENAZIME TC 99M;

AEROBIC CELL CULTURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL HYPOXIA; CELL LINE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG SYNTHESIS; DRUG UPTAKE; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; ORGAN; RADIOIODINATION; SARCOMA; STOMACH;

EID: 16844372834     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2005.01.004     Document Type: Article

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