Crystal structures of apo-form and binary/ternary complexes of Podophyllum secoisolariciresinol dehydrogenase, an enzyme involved in formation of health-protecting and plant defense lignans

Journal of Biological Chemistry

Volumn 280, Issue 13, 2005, Pages 12917-12926

  Youn, Buhyun ^a   Moinuddin, Syed G A ^a   Davin, Laurence B ^a   Lewis, Norman G ^a   Kang, Chulhee ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPLEXATION; CRYSTAL STRUCTURE; HYDROGEN BONDS; MOLECULAR STRUCTURE; MONOMERS; PLANTS (BOTANY); TERNARY SYSTEMS; TUMORS;

DEHYDROGENASE; HOMOTETRAMERS; PLICATIC ACID; RED CEDARS; TERNARY COMPLEXES;

ENZYMES;

ASPARTIC ACID; ENZYME; HYDROGEN; HYDROXYL GROUP; LIGNAN; LYSINE; PINORESINOL; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SECOISOLARICIRESINOL DEHYDROGENASE; SERINE; TYROSINE; UNCLASSIFIED DRUG;

ALPHA HELIX; ARTICLE; BETA CHAIN; CATALYSIS; CRYSTAL STRUCTURE; ENANTIOSELECTIVITY; ENZYME ANALYSIS; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROGEN BOND; PLANT DEFENSE; PODOPHYLLUM; PRIORITY JOURNAL; PROTEIN DOMAIN; REACTION ANALYSIS; STRUCTURE ANALYSIS;

ALCOHOL OXIDOREDUCTASES; AMINO ACID SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; FOURIER ANALYSIS; HYDROGEN BONDING; LIGHT; LIGNANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MODELS, STATISTICAL; MOLECULAR SEQUENCE DATA; OXIDOREDUCTASES; PLANT EXTRACTS; PLANT PHYSIOLOGY; PODOPHYLLUM; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SCATTERING, RADIATION; SEQUENCE HOMOLOGY, AMINO ACID; SUBSTRATE SPECIFICITY; TYROSINE;

EID: 16844372345     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413266200     Document Type: Article

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