Coulombic and hydrophobic interactions in the first intracellular loop are vital for bradykinin B2 receptor ligand binding and consequent signal transduction

Biochemistry

Volumn 44, Issue 14, 2005, Pages 5295-5306

  Yu, Jun ^a   Polgar, Peter ^a   Lubinsky, David ^a   Gupta, Megna ^a   Wang, Lei ^b   Mierke, Dale ^b   Taylor, Linda ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROPHOBICITY; MATHEMATICAL MODELS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE; ORGANIC COMPOUNDS; SIGNALING;

BOVINE RHODOPSIN; INTRACELLULAR LOOP (IC1); PLASMA MEMBRANE; X-RAY STRUCTURE;

BIOCHEMISTRY;

ANGIOTENSIN 2 RECEPTOR; BRADYKININ B2 RECEPTOR; LEUCINE; RHODOPSIN; SERINE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; DNA PRIMERS; ELECTROCHEMISTRY; ENZYME-LINKED IMMUNOSORBENT ASSAY; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; RATS; RECEPTOR, BRADYKININ B2; SIGNAL TRANSDUCTION;

EID: 16844372103     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi048288i     Document Type: Article

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