Studies on pharmacodynamic characteristics of aristolochic acid I in rats

Zhongguo Zhongyao Zazhi

Volumn 29, Issue 7, 2004, Pages 680-681

  Su, Tao ^a   Qu, Lei ^a   Zhang, Chun Li ^a   Cai, Shao Qing ^b   Li, Xiao Mei ^a  

^a PEKING UNIVERSITY FIRST HOSPITAL   (China)

^b PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

Author keywords

Aristolochic acid I; Binding rate of serum albumin; Distribution; Kidney; Pharmacokinetics

Indexed keywords

ARISTOLOCHIC ACID; ARISTOLOCHIC ACID I;

ANIMAL; ARISTOLOCHIA; ARTICLE; CHEMISTRY; KIDNEY; LIVER; MALE; MEDICINAL PLANT; METABOLIC CLEARANCE RATE; METABOLISM; ORAL DRUG ADMINISTRATION; RAT; TISSUE DISTRIBUTION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; ARISTOLOCHIA; ARISTOLOCHIC ACIDS; KIDNEY; LIVER; MALE; METABOLIC CLEARANCE RATE; PLANTS, MEDICINAL; RATS; RATS, WISTAR; TISSUE DISTRIBUTION;

EID: 16644375199     PISSN: 10015302     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Muniz Martinez M C, Nortier J, Vereerstraeten P, et al. Progression rate of Chinese herb nephropathy: impact of Aristolochia fangchi ingested dose. Nephrol Dial Transplant, 2002, 17(3):408.
2. Cosyns J P. Aristolochic acid and 'Chinese herbs nephropathy' : A review of the evidence to date. Drug Saf, 2003, 26(1):33.
3. Cosyns J P, Dehoux J P, Guiot Y, et al. Chronic aristolochic acid toxicity in rabbits: a model of Chinese herbs nephropathy? Kidney Int, 2001, 59(6):2164.
4. Nortier J L, Martinez M C, Schmeiser H H, et al. Urothelial carcinoma associated with the use of a Chinese herb (aristolochia fangchi). New Engl J Med, 2000, 342:1686.
5. Vanherwegham J L, Depierreux M, Tielemans C, et al. Rapidly progressive interstitial fibrosis in young women: association with slimming regimen including Chinese herbs. Lancet, 1993, 341:387.
6. Krumbiegel G, Hallensleben J, Mennicke W H. Studies on the metabolism of aristolochic acids I and II. Xenobiotica, 1987, 17 (8): 981.
7. Schmeiser H H, Bieler C A, Wiessler M, et al. Detection of DNA adducts formed by aristolochic acid in renal tissue from patients with Chinese herbs nephropathy. Cancer Research, 1996, 56:2025.
8. Levi M. Acute hepatitis in a patient using a Chinese herbal tea - a case report. Pharm World Sci, 1998, 20(1):43.
9. Rossiello M R, Laconi E, Rao P M, et al. Induction of hepatic nodules in the rat by aristolochic acid. Cancer Lett, 1993, 71(1-3):83.