Human milk α1,2-linked fucosylated oligosaccharides decrease risk of diarrhea due to stable toxin of E. coli in breastfed infants

Advances in Experimental Medicine and Biology

Volumn 554, Issue , 2004, Pages 457-461

  Newburg, David S ^a   Ruiz Palacios, Guillermo M ^b   Altaye, Mekibib ^c   Chaturvedi, Prasoon ^a   Guerrero, M Lourdes ^b   Meinzen Derr, Jareen K ^c   Morrow, Ardythe L ^c  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1,2 FUCOSYLOLIGOSACCHARIDE; CARBOHYDRATE DERIVATIVE; ESCHERICHIA COLI ENDOTOXIN; FUCOSE; OLIGOSACCHARIDE; UNCLASSIFIED DRUG; BACTERIAL TOXIN;

BREAST FEEDING; BREAST MILK; CONFERENCE PAPER; DIARRHEA; ESCHERICHIA COLI; FEMALE; FUCOSYLATION; HUMAN; INFANT; INFANT NUTRITION; MILK LEVEL; NORMAL HUMAN; PRIORITY JOURNAL; PROPHYLAXIS; RISK REDUCTION; ARTICLE; BLOOD GROUP LEWIS SYSTEM; CHEMISTRY; COHORT ANALYSIS; ENTEROBACTER INFECTION; IMMUNOLOGY; INFANTILE DIARRHEA; MALE; METABOLISM; NEWBORN; RISK FACTOR;

ESCHERICHIA COLI;

BACTERIAL TOXINS; COHORT STUDIES; DIARRHEA, INFANTILE; ESCHERICHIA COLI INFECTIONS; FEMALE; FUCOSE; HUMANS; INFANT; INFANT, NEWBORN; LEWIS BLOOD-GROUP SYSTEM; MALE; MILK, HUMAN; OLIGOSACCHARIDES; RISK FACTORS;

EID: 16644365677     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4757-4242-8_64     Document Type: Conference Paper

References (9)

1. Chaturvedi P, Warren CD, Ruiz-Palacios GM, Pickering LK, Newburg DS. Milk oligosaccharide profiles by reversed-phase HPLC of their perbenzoylated derivatives. Anal Biochem 1997;251:89-97.
2. Chaturvedi P, Warren CD, Altaye M, Morrow AL, Ruiz-Palacios G, Pickering LK, Newburg DS. Fucosylated human milk oligosaccharides vary between individuals and over the course of lactation. Glycobiology 2001;11:365-372.
3. Erney RM, Malone WT, Skelding MB, Marcon AA, Kleman-Leyer KM, O'Ryan ML, Ruiz-Palacios G, Hilty MD, Pickering LK, Prieto PA. Variability of human milk neutral oligosaccharides in a diverse population. J Pediatr Gastroenterol Nutr 2000;30:181-192.
4. Henry S, Oriol R, Samuelsson B. Lewis histo-blood group system and associated secretory phenotypes. Vox Sang 1995;69:166-182.
5. Huang P, Farkas T, Marionneau S, Zhong W, Ruvoen-Clouet DVM, Morrow AL, Altaye M, Pickering LK, Newburg DS, LePendu J, Jiang X. Noroviruses bind to human ABO, Lewis and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns. J Infect Dis 2003;188:19-31.
6. Newburg DS, Chaturvedi P, Crane JK, Cleary TG, Pickering LK. Fucosylated oligosaccharide(s) of human milk inhibits stable toxin of Escherichia coli. In: Agrawal VP, Sharma CB, Sah A, Zingde MD, editors. Complex Carbohydrates and Advances in Biosciences. Muzaffarnagar, India: Society of Biosciences; 1995; pp 199-226.
7. Ruiz-Palacios GM, Cervantes LE, Ramos P, Chavez-Munguia B, Newburg DS. Campylobacter jejuni binds intestinal H(O) antigen (Fuca1,2Gal b1,4GlcNAc), and fucosyloligosaccharides of human milk inhibit its binding and infection. J Biol Chem 2003;278:14112-14120.
8. Thurl S, Henker J, Siegel M, Tovar K, Sawatzki G. Detection of four human milk groups with respect to Lewis blood group dependent oligosaccharides. Glycoconj J 1997;14:795-799.
9. Viverge D, Grimmonprez L, Cassanas G, Bardet L, Solere M. Discriminant carbohydrate components of human milk according to donor secretor types. J Pediatr Gastroenterol Nutr 1990;11:365-370.