Disruption of C/EBPα function in acute myeloid leukemia

New England Journal of Medicine

Volumn 351, Issue 23, 2004, Pages 2370-2372

  Fröhling, Stefan ^a   Döhner, Hartmut ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN ALPHA; GENE PRODUCT; TRANSCRIPTION FACTOR;

ACUTE GRANULOCYTIC LEUKEMIA; CELL DIFFERENTIATION; CORRELATION ANALYSIS; GENE FUNCTION; GENE MUTATION; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMAN; LEUKEMOGENESIS; MYELOID PROGENITOR CELL; PRIORITY JOURNAL; PROGNOSIS; REVIEW; ANIMAL; GENETICS; METABOLISM; MUTATION; NOTE;

ANIMALS; CCAAT-ENHANCER-BINDING PROTEIN-ALPHA; HUMANS; LEUKEMIA, MYELOCYTIC, ACUTE; MUTATION; PROGNOSIS; TRANSCRIPTION FACTORS;

EID: 16444387654     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMp048241     Document Type: Review

References (4)

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2. Tenen DG, Disruption of differentiation in human cancer: AML shows the way. Nat Rev Cancer 2003;3:89-101.
3. Song WJ, Sullivan MG, Legare RD, et al. Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia. Nat Genet 1999;23:166-75.
4. Fröhling S, Schlenk RF, Stolze I, et al. CEBPA mutations in younger adults with acute myeloid leukemia and normal cytogenetics: prognostic relevance and analysis of cooperating mutations. J Clin Oncol 2004;22:624-33.