Selection experiments with dynamic combinatorial libraries: The importance of the target concentration

Chemical Communications

Volumn , Issue 11, 2005, Pages 1471-1473

  Saur, Isabelle ^a   Severin, Kay ^a  

^a EPFL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

LITHIUM; LITHIUM SULFATE;

AQUEOUS SOLUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CHEMICAL ANALYSIS; CHEMICAL COMPOSITION; CHEMICAL MODEL; CHEMICAL REACTION; COMBINATORIAL CHEMISTRY; COMBINATORIAL LIBRARY; COMPLEX FORMATION; COMPUTER SIMULATION; CONCENTRATION (PARAMETERS); CORRELATION ANALYSIS; MASS SPECTROMETRY; PH; PROTON NUCLEAR MAGNETIC RESONANCE; RECEPTOR BINDING; TECHNIQUE;

EID: 16444387032     PISSN: 13597345     EISSN: None     Source Type: Journal    
DOI: 10.1039/b417824f     Document Type: Article

References (19)

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16. 4Pr) at δ = 1.78, 1.82, 1.85 and 1.86 ppm. One signal is expected for AAA, one for ABB and two for AAB. The relative intensity of the signals was approximately equal, which points to a ratio of AAA: AAB: ABB = 1: 3: 3.
17. + guest is slow on the NMR timescale. This allows us to calculate the association constant by integrating the respective signals.
18. + complexes.
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