Recent developments in dynamic combinatorial chemistry

Current Opinion in Chemical Biology

Volumn 6, Issue 3, 2002, Pages 321-327

  Otto, Sijbren ^a   Furlan, Ricardo LE ^b   Sanders, Jeremy KM ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSIDAD NACIONAL DE ROSARIO   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

LIGAND; RECEPTOR;

COMBINATORIAL CHEMISTRY; DNA TEMPLATE; MACROMOLECULE; MOLECULAR RECOGNITION; PRODUCTIVITY; PROTEIN FOLDING; REVIEW;

EID: 0036603782     PISSN: 13675931     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1367-5931(02)00331-9     Document Type: Review

References (38)

1. Supramolecular templating in thermodynamically controlled synthesis
2. 'Living' macrolactonisation: Thermodynamically-controlled cyclisation and interconversion of oligocholates
3. Dynamic combinatorial chemistry
4. Drug discovery by dynamic combinatorial libraries
5. Dynamic covalent chemistry
6. From molecular diversity to template-directed self-assembly - New trends in metallo-supramolecular chemistry
7. Redistribution of terpy ligands - Approaches to new dynamic combinatorial libraries
8. Chloroform-soluble Schiff-base Zn(II) or Cd(II) complexes from a dynamic combinatorial library
9. Combinatorial libraries of metal-ligand assemblies with an encapsulated guest molecule
10. Amplification of a cyclic mixed-metalloporphyrin tetramer from a dynamic combinatorial library through orthogonal metal coordination
11. Libraries of non-covalent hydrogen-bonded assemblies; combinatorial synthesis of supramolecular systems
12. Guest-templated selection and amplification of a receptor by noncovalent combinatorial synthesis
13. Covalent capture of dynamic hydrogen-bonded assemblies
14. Diversity and selection in self-assembled tetrameric capsules
15. Thermodynamically-controlled cyclisation and interconversion of oligocholates: Metal ion templated 'living' macrolactonisation
16. Synthesis under reversible conditions of cyclic porphyrin dimers using palladium-catalysed allyl transesterification
17. Nonspecific protease-catalyzed hydrolysis/synthesis of a mixture of peptides: Product diversity and ligand amplification by a molecular trap
18. Dioxadiazadecalin/salen tautomeric macrocycles and complexes: Prototypal dynamic combinatorial virtual libraries
19. Imine exchange in O-aryl and O-alkyl oximes as a base reaction for aqueous 'dynamic' combinatorial libraries. A kinetic and thermodynamic study
20. Dynamic combinatorial libraries of pseudo-peptide hydrazone macrocycles
21. Libraries for receptor-assisted combinatorial synthesis (RACS). The olefin metathesis reaction
22. Dynamic combinatorial libraries of macrocyclic disulfides in water
23. In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A
24. Double-level 'orthogonal' dynamic combinatorial libraries on transition metal template
25. Electrospray ionisation Fourier-transform ion cyclotron resonance mass spectrometry of dynamic combinatorial libraries
26. Synthesis and mass spectrometry studies of branched oxime ether libraries. Mapping the substitution motif via linker stability and fragmentation pattern
27. A new cyclic pseudopeptide receptor for Li+ from a dynamic combinatorial library
28. Identification and isolation of a receptor for N-methyl alkylammonium salts: Molecular amplification in a pseudo-peptide dynamic combinatorial library
29. Molecular amplification in a dynamic system by ammonium cations
30. Molecular paneling via coordination
31. Dynamic assembly of coordination boxes from (en)Pd(II) unit and a rectangular panel-like ligand: NMR, CSI-MS, and X-ray studies
32. RNA-selective coordination complexes identified via dynamic combinatorial chemistry
33. Dynamic deconvolution of a pre-equilibrated dynamic combinatorial library of acetylcholinesterase inhibitors
34. A virtual library approach to investigate protein folding and internal packing
35. Programmed self-sorting of coiled coils with leucine and hexafluoroleucine cores
36. Folding-driven synthesis of oligomers
37. How to synthesize macrocycles efficiently by using virtual combinatorial libraries
38. Target-induced formation of neuramidase inhibitors from in vitro virtual combinatorial libraries