A rapid catalytic asymmetric synthesis of 1,3,4-trisubstituted pyrrolidines

Tetrahedron Letters

Volumn 45, Issue 16, 2004, Pages 3265-3268

  Belyk, Kevin M ^a   Beguin, Charlotte D ^a   Palucki, Michael ^a   Grinberg, Nelu ^a   DaSilva, Jimmy ^a   Askin, David ^a   Yasuda, Nobuyoshi ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

1,3 Dipolar cycloaddition; Arylboronic acid; Asymmetric 1,4 addition; Pyrrolidine; Rhodium catalyzed

Indexed keywords

AZOMETHINE YLIDE; BORONIC ACID DERIVATIVE; PYRROLINE DERIVATIVE; RHODIUM;

ARTICLE; ARYLATION; ASYMMETRIC CATALYSIS; ASYMMETRIC SYNTHESIS; BIOAVAILABILITY; CATALYST; CYCLOADDITION; ENANTIOSELECTIVITY; POLARIZATION; SUBSTITUTION REACTION;

EID: 1642619506     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2004.02.114     Document Type: Article

References (17)

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17. 3OD): δ 177.91, 140.96, 133.30, 131.50, 130.74, 130.37, 130.00, 128.75, 128.54, 61.10, 59.89, 58.55, 53.49, 48.55 ppm. Results for all NOE experiments can be found in the Supplementary data section.