Validity of in vivo [123I]β-CIT SPECT in detecting MDMA-induced neurotoxicity in rats

European Neuropsychopharmacology

Volumn 14, Issue 3, 2004, Pages 185-189

  De Win, Maartje M L ^a   De Jeu, Rogier A M ^a   De Bruin, Kora ^a   Habraken, Jan B A ^a   Reneman, Liesbeth ^a   Booij, Jan ^a   Den Heeten, Gerard J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

CIT; MDMA; Neurotoxicity; Serotonin transporters; Small animal imaging; SPECT

Indexed keywords

3,4 METHYLENEDIOXYMETHAMPHETAMINE; DOPAMINE TRANSPORTER; IODINE 123; SEROTONIN TRANSPORTER; TRACER; 3BETA (4 IODOPHENYL) 2BETA TROPANECARBOXYLIC ACID METHYL ESTER; CARRIER PROTEIN; COCAINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; MEMBRANE PROTEIN; NERVE PROTEIN; PSYCHEDELIC AGENT; RADIOACTIVE IODINE; RADIOPHARMACEUTICAL AGENT; SLC6A4 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC TRANSMISSION; IN VIVO STUDY; MALE; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RADIOACTIVITY; RAT; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; STATISTICAL SIGNIFICANCE; THALAMUS; ANIMAL; BRAIN; COMPARATIVE STUDY; DRUG EFFECT; HISTOLOGY; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PROTEIN BINDING; RADIOASSAY; SCINTISCANNING; TIME; VALIDATION STUDY; WISTAR RAT;

ANIMALS; BRAIN; CARRIER PROTEINS; COCAINE; HALLUCINOGENS; IODINE RADIOISOTOPES; MAGNETIC RESONANCE IMAGING; MALE; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; N-METHYL-3,4-METHYLENEDIOXYAMPHETAMINE; NERVE TISSUE PROTEINS; PROTEIN BINDING; RADIOLIGAND ASSAY; RADIOPHARMACEUTICALS; RATS; RATS, WISTAR; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 1642587801     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0924-977X(03)00101-9     Document Type: Article

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