Expression of cathepsin B is related to tumorigenicity of breast cancer cell lines

Radiology and Oncology

Volumn 37, Issue 4, 2003, Pages

  Zajc, Irena ^a   Frangež, Leonida ^a   Lah, Tamara T ^a  

^a NATIONAL INSTITUTE OF BIOLOGY   (Slovenia)

Author keywords

Breast neoplasms; Cathepsin B; Neoplasm invasiveness; Tumor cells, cultured

Indexed keywords

CATHEPSIN B; CATHEPSIN L; MESSENGER RNA; STEFIN A; STEFIN B;

ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER CELL CULTURE; CANCER INVASION; CANCER INVASIVENESS; CARCINOGENICITY; CELL STRAIN MCF 7; CELL STRAIN MDA 231; CELL STRAIN MDA MB435; CELL STRAIN MDA MB468; HUMAN; HUMAN CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TUMOR GROWTH;

EID: 1642569550     PISSN: 13182099     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Zajc I, Sever N, Bervar A, Lah TT. Expression of cysteine peptidase cathepsin L and its inhibitors stefins A and B in relation to tumorigenicity of breast cancer cell lines. Cancer Lett 2002; 187: 185-90.
2. Dickinson DP. Cysteine peptidases of mammals: Their biological roles and potential effects in the oral cavity and other tissues in health and disease. Crit Rev Oral Biol Med 2002; 13(3): 238-75.
3. Kos J, Lah TT. Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer. Oncol Rep 1998; 5: 1349-61.
4. Yan S, Sameni M, Sloane BF. Cathepsin B and human tumor progression. Biol Chem 1998; 379: 113-23.
5. Foekens JA, Kos J, Peters HA, Kraöovec M, Look MP, Cimerman N, et al. Prognostic significance of cathepsins B and L in primary human breast cancer. J Clin Oncol 1998; 16: 1013-21.
6. Thomssen C, Schmitt M, Goretzki L, Oppelt P, Pache L, Dettmar P, et al. Prognostic value of the cysteine proteases cathepsin B and cathepsin L in human breast cancer. Clin Cancer Res 1995; 1: 741-46.
7. Lah TT, Kos J, Blejec A, Frkovič-Grazio S, Golouh R, Vrhovec I, Turk V. The expression of lysosomal proteinases and their Inhibitors in breast cancer: Possible relationship to prognosis of the disease. Pathol Oncol Res 1997; 3: 221-33.
8. Lah TT, Čerček M, Blejec A, Kos J, Gorodetsky E, Somers R, et al. Cathepsin B, a prognostic indicator in lymph node-negative breast carcinoma patients: comparison with cathepsin D, cathepsin L and other clinical indicators. Clin Cancer Res 2000; 6: 578-84.
9. Levičar N, Kos J, Blejec A, Golouh R, Vrhovec I, Frkovič-Grazio S, Lah TT. Comparison of potential biological markers cathepsin B, cathepsin L, stefin A and stefin B with urokinase and plasminogen activator inhibitor-1 and clinicopathological data of breast carcinoma patients. Cancer Detect Prev 2002; 26: 42-49.
10. Turk V, Bode W. The cystatins: protein inhibitors of cysteine proteinases. FEBS Lett 1991; 285: 213-19.
11. Calkins CC, Sloane BF. Mammalian cysteine protease inhibitors: biochemical properties and possible roles in tumor progression. Biol Chem Hoppe Seyler 1995; 376: 71-80.
12. Lah TT, Kokalj-Kunovar M, ätrukelj B, Pungerčar J, Barlič-Maganja D, Drobnǐ-Koöorok M, et al. Stefins and lysosomal cathepsins B, L and D in human breast carcinoma. Int J Cancer 1992; 50: 36-44.
13. Kuopio T, Kankaanranta A, Jalava P, Kronqvist P, Kotkansalo T, Weber, et al. Cysteine proteinase inhibitor cystatin A in breast cancer. Cancer Res 1998; 58: 432-36.
14. Levičar N, Nuttall RK, Lah TT. Proteases in human brain tumours. Acta Neurochir 2003; 145: 825-38.
15. Everts V, Creemers LB, Docherty AJP, Beertsen W. Intracellular versus extracellular digestion of collagen. In: Davidivich Z and Norton LA, editors. Biological Mechanisms of Tooth Movement and Craniofacial Adaptation. Harvard Society for Advancement of Orthodontics, Boston: Ma Press; 1996. p. 309-16.
16. Premzl A, Zavarönik-Bergant V, Turk V, Kos J. Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro. Exp Cell Res 2003; 283: 206-14.
17. Szpaderska AM, Frankfater A. An intracellular form of cathepsin B contributes to invasiveness in cancer. Cancer Res 2001; 61: 3493-500.
18. Sameni M, Dosescu J, Sloane BF. Imaging proteolysis by living human glioma cells. Biol Chem 2001; 382: 785-88.
19. Bervar A, Zajc I, Sever N, Katunuma N, Sloane BF, Lah TT. Invasiveness of transformed human breast epithelial cell lines is related to cathepsin B and inhibited by cysteine proteinase inhibitors. Biol Chem 2003; 384: 447-55.
20. Xin H, Stephans JC, Duan X, Harrowe G, Kim E, Grieshammer U et al. Identification of a novel aspartic-like peptidase differentially expressed in human breast cancer cell lines. Biochim Biophys Acta 2000; 1501: 125-37.
21. Price JE, Polyzos A, Zhang RD, Daniels LM. Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 1990; 50: 717-21.
22. Thompson EW, Paik S, Brünner N, Sommers CL, Zugmaier G, Clarke R, et al. Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 1992; 150: 534-44.
23. Deussing J, Roth W, Saftig P, Peters C, Ploegh HL, Villadangos JA. Cathepsin B and D are dispensable for major histocompatibility complex class II-mediated antigen presentation. Proc Natl Acad Sci USA 1998; 95: 4516-21.
24. Nakagawa T, Roth W, Wong P, Nelson A, Farr A, Deussing J, et al. Cathepsin L: critical role in li degradation and CD4 T cell selection in the thymus. Science 1998; 280: 450-3.
25. Yan, S, Berquin IM, Troen, BR, Sloane BF. Transcription of human cathepsin B is mediated by Sp1 and Ets family factors in glioma. DNA Cell Biol 2000; 19: 79-1.
26. Chauhan SS, Popescu NC, Ray D, Fleischmann R, Gottesman MM, Troen BR. Cloning, genomic organisation and chromosomal localisation of human cathepsin L. J Biol Chem 1993; 268(2); 1039-45.
27. Mehtani S, Gong Q, Panella J, Subbiah S, Peffley DM, Frankfater A. In vivo expression of an alternatively spliced human tumour message that encodes a truncated form of cathepsin B. J Biol Chem 1998; 273(21); 13236-44.
28. Abudula A, Rommerskirsch W, Weber E, Gunther D, Wiederanders B. Splice variants of human cathepsin L mRNA show different expression rates. Biol Chem 2001; 382: 1583-91.
29. Frosch BA, Berquin I, Emmert-Buck M, Moin K, Sloane BF. Molecular recognition, membrane association and secretion of tumour cathepsin B. AMPIS 1999; 107: 28-37.
30. Lah TT, Calaf G, Kalman E, Shinde BG, Somers R, Russo J, et al. Cathepsins D, B, and L in transformed human breast epithelial cells. Breast Cancer Res Treat 1996; 39: 221-33.
31. Turk D, Gunčar G. Lysosomal cysteine proteases (cathepsins): promising targets. Acta Crystallogr D Biol Crystallogr 2003; 59: 203-13.
32. Lah TT, Moin K, Clifford JL, Helmer KM, Day NA, Crissman JD, et al. Inhibitory, properties of low molecular mass cysteine proteinase inhibitors from human sarcoma. Biochim Biophys Acta 1989; 993: 63-73.