Fibroblast growth factor receptor-1 interacts with the T-cell receptor signalling pathway

Immunology and Cell Biology

Volumn 81, Issue 6, 2003, Pages 440-450

  Byrd, Victor M ^a   Kilkenny, Dawn M ^a   Dikov, Michael M ^a   Reich, Martha B ^a   Rocheleau, Jonathan V ^a   Armistead, Wade J ^a   Thomas, James W ^a   Miller, Geraldine G ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Growth factors; Protein kinases; Signal transduction; T cell receptors; Transcription factors

Indexed keywords

ANTIGEN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR RECEPTOR 1; NUCLEAR FACTOR; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR;

CELL STIMULATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; INFLAMMATION; INJURY; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REVIEW; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

ACTIVE TRANSPORT, CELL NUCLEUS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD3; CELL MEMBRANE; FIBROBLAST GROWTH FACTORS; HUMANS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); NFATC TRANSCRIPTION FACTORS; PHOSPHORYLATION; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 1; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 1642546957     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.2003.01199.x     Document Type: Review

References (58)

1. Mohammadi M, Honegger AM, Rotin D et al. A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (flg) is a binding site for the SH2 domain of phospholipase C-gamma 1. Mol. Cell. Biol. 1991; 11: 5068-78.
2. 2+ flux but not mitogenesis. Nature (London) 1992; 358: 678-81.
3. Tsuda T, Kaibuchi K, Kawahara Y, Fukuzaki H, Takai Y. Induction of protein kinase C activation and Ca2+ mobilization by fibroblast growth factor in Swiss 3T3 cells. FEBS Lett. 1985; 191: 205-10.
4. Kouhara H, Hadari YR, Spivak-Kroizman T et al. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 1997; 89: 693-702.
5. Janet T, Labourdette G, Sensenbrenner M, Pettman B. Mitogenic growth factors regulate differentially early gene mRNA expression, a study on two clones of 3T3 fibroblasts. Exp. Cell Res. 1999; 198: 305-14.
6. Jaakkola P, Vihinen T, Maata A, Jalkanen M. Activation of an enhancer on the syndecan-1 gene is restricted to fibroblast growth factor family members in mesenchymal cells. Mol. Cell. Biol. 1997; 17: 3210-9.
7. Byrd VM, Zhao XM, McKeehan WL, Miller GG, Thomas JW. Expression and functional expansion of fibroblast growth factor receptor T cells in rheumatoid synovium and peripheral blood of patients with rheumatoid arthritis. Arthritis Rheum. 1996; 39: 914-22.
8. + T cells by fibroblast growth factor-1. J. Immunol. 1995; 155: 3904-11.
9. Byrd VM, Ballard DW, Miller GG, Thomas JW. Fibroblast growth factor-1 (FGF-1) enhances IL-2 production and nuclear translocation of NF-kB in FGF receptor-bearing Jurkat T cell. J. Immunol. 1999; 162: 5853-9.
10. Sano H, Engleka K, Mathern P et al. Coexpression of phosphotyrosine- containing proteins, platelet-derived growth factor-B, and fibroblast growth factor-1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with adjuvant or streptococcal cell wall arthritis. J. Clin. Invest. 1993; 91: 553-76.
11. Zhao XM, Yeoh TK, Frist WH, Porterfield DL, Miller GG. Induction of acidic fibroblast growth factor and full-length platelet derived growth factor expression in human cardiac allografts: analysis by PCR, in situ hybridization, and immunohistochemistry. Circulation 1994; 90: 677-85.
12. Kerby JD, Verran DJ, Luo KL et al. Immunolocalization of FGF-1 and receptors in glomerular lesions associated with chronic human renal allograft rejection. Transplantation 1996; 62: 190-200.
13. Meij JT, Sheikh F, Jimenez SK, Nickerson PW, Kardami E, Cattini PA. Exacerbation of myocardial injury in transgenic mice overexpressing FGF-2 is T cell dependent. Am. J. Physiol. Heart Circ. Physiol. JID-100901228 2002; 282: H547-H555.
14. Yamashita A, Yonemitsu Y, Okano S et al. Fibroblast growth factor-2 determines severity of joint disease in adjuvant-induced arthritis in rats. J. Immunol. JID - 2985117r 2002; 168: 450-7.
15. Johnson HM, Torres BA. Peptide growth factors PDGF, EGF, and FGF regulate interferon-gamma production. J. Immunol. 1985; 134: 2824-6.
16. Hoshi S, Goto M, Koyama N, Nomoto K, Tanaka H. Regulation of vascular smooth muscle cell proliferation by nuclear factor-kappaB and its inhibitor, I-kappaB. J. Biol. Chem. 2000; 275: 883-9.
17. Selzman CH, Shames BD, McIntyre RC, Banerjee A, Harken AH. The NFkappaB inhibitory peptide, IkappaBalpha, prevents human vascular smooth muscle proliferation. Ann. Thorac. Surg. 1999; 67: 1227-31.
18. Feske S, Draeger R, Peter HH, Eichmann K, Rao A. The duration of nuclear residence of NFAT determines the pattern of cytokine expression in human SCID T cells. J. Immunol. 2000; 165: 297-305.
19. Feske S, Giltnane J, Dolmetsch R, Staudt LM, Rao A. Gene regulation mediated by calcium signals in T lymphocytes. Nat. Immunol. 2001; 2: 316-24.
20. Dikov MM, Reich MB, Dworkin L, Thomas JW, Miller GG. A functional fibroblast growth factor-1 immunoglobulin fusion protein. J. Biol. Chem. 1998; 273: 15811-7.
21. Straus DB, Weiss A. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell 1992; 70: 585-93.
22. Stewart SJ, Fujimoto J, Levy R. Human T lymphocytes and monocytes bear the same Leu-3 antigen. J. Immunol. 1986; 136: 3773-8.
23. Moroi Y, Koga Y, Nakamura K, Ohtsu M, Kimura G, Nomoto K. Accumulation of p60lck in HTLV-I-transformed T cell lines detected by an anti-lck monoclonal antibody, MOL 171. Jpn J. Cancer Res. 1991; 82: 909-15.
24. Schreiber E, Matthias P, Muller MM, Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells. Nucl. Acids Res. 1989; 17: 6419.
25. Lewis LA, Chung CD, Chen J et al. The Lck SH2 phosphotyrosine binding site is critical for efficient TCR-induced processive tyrosine phosphorylation of the zeta-chain and IL-2 production. J. Immunol. 1997; 159: 2292-300.
26. Zhan X, Plourde C, Hu X, Friesel R, Maciag T. Association of fibroblast growth factor receptor-1 with c-Src correlates with association between c-Src and cortactin. J. Biol. Chem. 1994; 269: 20221-4.
27. Yayon A, Ma YS, Safran M, Klagsbrun M, Halaban R. Suppression of autocrine cell proliferation and tumorigenesis of human melanoma cells and fibroblast growth factor transformed fibroblasts by a kinase-deficient FGF receptor 1: evidence for the involvement of Src-family kinases. Oncogene 1997; 14: 2999-3009.
28. Landgren E, Blume-Jensen P, Courtneidge SA, Claesson-Welsh L. Fibroblast growth factor receptor-1 regulation of Src family kinases. Oncogene 1995; 10: 2027-35.
29. Soula M, Rothhut B, Camoin L et al. Anti-CD3 and phorbol ester induce distinct phosphorylated sites in the SH2 domain of p56lck. J. Biol. Chem. 1993; 268: 27420-7.
30. Veillette A, Horak ID, Horak EM, Bookman MA, Bolen JB. Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation. Mol. Cell Biol. 1988; 8: 4353-61.
31. Marth JD, Lewis DB, Cooke MP et al. Lymphocyte activation provokes modification of a lymphocyte-specific protein tyrosine kinase (p56lck). J. Immunol. 1989; 142: 2430-7.
32. Danielian S, Fagard R, Alcover A, Acuto O, Fischer S. The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2. Eur. J. Immunol. 1989; 19: 2183-9.
33. Hanke JH, Gardner JP, Dow RL et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck-and FynT-dependent T-cell activation. J. Biol. Chem. 1996; 271: 695-701.
34. Waltenberger J, Uecker A, Kroll J et al. A dual inhibitor of platelet-derived growth factor beta-receptor and Src kinase activity potently interferes with motogenic and mitogenic responses to PDGF in vascular smooth muscle cells. A novel candidate for prevention of vascular remodeling. Circ. Res. 1999; 85: 12-22.
35. Danielian S, Alcover A, Polissard L et al. Both T cell receptor (TcR) -CD3 complex and CD2 increase the tyrosine kinase activity of p56lck. CD2 can mediate TcR-CD3-independent and CD45-dependent activation of p56lck. Eur. J. Immunol. 1992; 22: 2915-21.
36. Feige JJ, Baird A. Glycosylation of the basic fibroblast growth factor receptor. The contribution of carbohydrate to receptor function. J. Biol. Chem. 1988; 263: 14023-9.
37. Keegan K, Meyer S, Hayman MJ. Structural and biosynthetic characterization of the fibroblast growth factor receptor 3 (FGFR-3) protein. Oncogene 1991; 6: 2229-36.
38. Prudovsky IA, Savion N, LaVallee TM, Maciag T. The nuclear trafficking of extracellular fibroblast growth factor (FGF)-1 correlates with the perinuclear association of the FGF receptor-1alpha isoforms but not the FGF receptor-1beta isoforms. J. Biol. Chem. 1996; 271: 14198-205.
39. Jain J, McCaffrey PG, Valge-Archer VE, Rao A. Nuclear factor of activated T cells contains Fos and Jun. Nature 1992; 356: 801-4.
40. Yaseen NR, Park J, Kerppola T, Curran T, Sharma S. A central role for Fos in human B-and T-Cell NFAT (Nuclear Factor of Activated T Cells): an acidic region is required for In vitro assembly. Mol. Cell Biol. 1994; 14: 6886-95.
41. Park J, Takeuchi A, Sharma S. Characterization of a new isoform of the NFAT (Nuclear Factor of Activated T Cells) gene family member NFATc. J. Biol. Chem. 1996; 271: 20914-21.
42. Rao A, Luo C, Hogan PG. Transcription factors of the NFAT family: Regulation and function. Annu. Rev. Immunol. 1997; 15: 707-47.
43. McCaffrey PG, Luo C, Kerppola TK et al. Isolation of the cyclosporin-sensitive T cell transcription factor NFATp. EMBO J. 1993; 262: 750-4.
44. Northrop JP, Ho SN, Chen L et al. NF-AT components define a family of transcription factors targeted in T-cell activation. Nature 1994; 369: 497-502.
45. Hoey T, Sun YL, Williamson, Xu X. Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins. Immunity 1995; 2: 461-72.
46. Lyakh L, Ghosh P, Rice NR. Expression of NFAT-family proteins in normal human T cells. Mol. Cell Biol. 1997; 17: 2475-84.
47. Amasaki Y, Masuda ES, Imamura R, Arai K-I, Arai N. Distinct NFAT family proteins are involved in the nuclear NFAT-DNA binding complexes from human thymocyte subsets. J. Immunol. 1998; 160: 2324-33.
48. Ruff VA, Leach KL. Direct demonstration of NFATp dephosphorylation and nuclear localization in activated HT-2 cells using a specific NFATp polyclonal antibody. J. Biol. Chem. 1995; 270: 22602-7.
49. Park J, Yaseen NR, Hogan PG, Rao A, Sharma S. Phosphorylation of the transcription factor NFATp inhibits its DNA binding activity in cyclosporin A-treated human B and T cells. J. Biol. Chem. 1995; 270: 20653-9.
50. Ranger AM, Oukka M, Rengarajan J, Glimcher LH. Inhibitory function of two NFAT family members in lymphoid homostasis and Th2 development. Immunity 1998; 9: 627-35.
51. Burgess WH, Shaheen AM, Ravera M, Jaye M, Donahue PJ, Winkles JA. Possible dissociation of the heparin-binding and mitogenic activities of heparin-binding (acidic fibroblast) growth factor-1 from its receptor-binding activities by site-directed mutagenesis of a single lysine residue. J. Cell Biol. 1990; 111: 2129-38.
52. Sherman MA, Powell DR, Weiss DL, Brown MA. NF-ATc isoforms are differentially expressed and regulated in murine T and mast cells. J. Immunol. 1999; 162: 2820-8.
53. LaVallee TM, Prudovsky IA, McMahon GA, Hu X, Maciag T. Activation of the MAP kinase pathway by FGF-1 correlates with cell proliferation induction while activation of the Src pathway correlates with migration. J. Cell. Biol. 1998; 141: 1647-58.
54. Liu J, Huang C, Zhan X. Src is required for cell migration and shape changes induced by fibroblast growth factor 1. Oncogene 1999; 18: 6700-6.
55. Winterpacht A, Hilbert K, Stelzer C et al. A novel mutation in FGFR-3 disrupts a putative N-glycosylation site and results in hypochondroplasia. Physiol. Genomics 2000; 2: 9-12.
56. Buckhaults P, Chen L, Fregien N, Pierce M. Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene. J. Biol. Chem. 1997; 272: 19575-81.
57. Mohammadi M, Dionne CA, Li W et al. Point mutation in FGF receptor eliminates phosphatidylinositol hydrolysis without affecting mitogenesis. Nature 1992; 358: 681-4.
58. Wang JK, Xu H, Li HC, Goldfarb M. Broadly expressed SNT-like proteins link FGF receptor stimulation to activators of Ras. Oncogene 1996; 13: 721-9.