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Volumn 286, Issue 2 49-2, 2004, Pages

Tyrphostin AG 126 inhibits development of postoperative ileus induced by surgical manipulation of murine colon

Author keywords

Interleukin 1 ; Macrophage; Monocyte chemoattractant protein 1; Protein tyrosine kinase; Smooth muscle

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR; TYRPHOSTIN; TYRPHOSTIN AG 126; UNCLASSIFIED DRUG;

EID: 1642539148     PISSN: 01931857     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpgi.00312.2003     Document Type: Article
Times cited : (22)

References (44)
  • 1
    • 0027963539 scopus 로고
    • Mycobacterial cell wall components induce the production of TNF-α, IL-1, and IL-6 by bovine monocytes and the murine macrophage cell line RAW 264.7
    • Adams JL and Czuprynski CJ. Mycobacterial cell wall components induce the production of TNF-α, IL-1, and IL-6 by bovine monocytes and the murine macrophage cell line RAW 264.7. Microb Pathog 16: 401-411, 1994.
    • (1994) Microb Pathog , vol.16 , pp. 401-411
    • Adams, J.L.1    Czuprynski, C.J.2
  • 2
    • 0031432550 scopus 로고    scopus 로고
    • IL-6-regulated transcription factors
    • Akira S. IL-6-regulated transcription factors. Int J Biochem Cell Biol 29: 1401-1418, 1997.
    • (1997) Int J Biochem Cell Biol , vol.29 , pp. 1401-1418
    • Akira, S.1
  • 3
    • 0035176191 scopus 로고    scopus 로고
    • Biological activity of tyrosine kinase inhibitors: Novel agents for psoriasis therapy
    • Ben-Bassat H. Biological activity of tyrosine kinase inhibitors: novel agents for psoriasis therapy. Curr Opin Investig Drugs 2: 1539-1545, 2001.
    • (2001) Curr Opin Investig Drugs , vol.2 , pp. 1539-1545
    • Ben-Bassat, H.1
  • 4
    • 0033623538 scopus 로고    scopus 로고
    • Protein kinase C-α but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH2-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1β: Involvement of sequential activation of tyrosine kinase, nuclear factor-κB-inducing kinase, and IκB kinase 2
    • Chen CC, Chen JJ, and Chou CY. Protein kinase C-α but not p44/42 mitogen-activated protein kinase, p38, or c-Jun NH2-terminal kinase is required for intercellular adhesion molecule-1 expression mediated by interleukin-1β: involvement of sequential activation of tyrosine kinase, nuclear factor-κB-inducing kinase, and IκB kinase 2. Mol Pharmacol 58: 1479-1489, 2000.
    • (2000) Mol Pharmacol , vol.58 , pp. 1479-1489
    • Chen, C.C.1    Chen, J.J.2    Chou, C.Y.3
  • 7
    • 0033861096 scopus 로고    scopus 로고
    • JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells
    • De Vos J, Jourdan M, Tarte K, Jasmin C, and Klein B. JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells. Br J Haematol 109: 823-828, 2000.
    • (2000) Br J Haematol , vol.109 , pp. 823-828
    • De Vos, J.1    Jourdan, M.2    Tarte, K.3    Jasmin, C.4    Klein, B.5
  • 12
    • 0031657132 scopus 로고    scopus 로고
    • Lipopolysaccharide activates jejunal muscularis macrophages and suppresses circular muscularis activity
    • Eskandari MK, Kalff JC, Lee KK, and Bauer AJ. Lipopolysaccharide activates jejunal muscularis macrophages and suppresses circular muscularis activity. Transplant Proc 30: 2670, 1998.
    • (1998) Transplant Proc , vol.30 , pp. 2670
    • Eskandari, M.K.1    Kalff, J.C.2    Lee, K.K.3    Bauer, A.J.4
  • 13
    • 0020284279 scopus 로고
    • Relationship of duration of postoperative ileus to extent and site of operative dissection
    • Graber JN, Schulte WJ, Condon RE, and Cowles VE. Relationship of duration of postoperative ileus to extent and site of operative dissection. Surgery 92: 87-92, 1982.
    • (1982) Surgery , vol.92 , pp. 87-92
    • Graber, J.N.1    Schulte, W.J.2    Condon, R.E.3    Cowles, V.E.4
  • 15
    • 0035079188 scopus 로고    scopus 로고
    • Impaired gut contractility following hemorrhagic shock is accompanied by IL-6 and G-CSF production and neutrophil infiltration
    • a. Hierholzer C, Kalff JC, Chakraborty A, Watkins SC, Billiar TR, Bauer AJ, and Tweardy DJ. Impaired gut contractility following hemorrhagic shock is accompanied by IL-6 and G-CSF production and neutrophil infiltration. Dig Dis Sci 46: 230-241, 2001.
    • (2001) Dig Dis Sci , vol.46 , pp. 230-241
    • Hierholzer, C.1    Kalff, J.C.2    Chakraborty, A.3    Watkins, S.C.4    Billiar, T.R.5    Bauer, A.J.6    Tweardy, D.J.7
  • 16
    • 0032844633 scopus 로고    scopus 로고
    • Products of cyclooxygenase-2 catalysis regulate postoperative bowel motility
    • Josephs MD, Cheng G, Ksontini R, Moldawer LL, and Hocking MP. Products of cyclooxygenase-2 catalysis regulate postoperative bowel motility. J Surg Res 86: 50-54, 1999.
    • (1999) J Surg Res , vol.86 , pp. 50-54
    • Josephs, M.D.1    Cheng, G.2    Ksontini, R.3    Moldawer, L.L.4    Hocking, M.P.5
  • 17
    • 0032825171 scopus 로고    scopus 로고
    • Biphasic response to gut manipulation and temporal correlation of cellular infiltrates and muscle dysfunction in rat
    • Kalff JC, Buchholz BM, Eskandari MK, Hierholzer C, Schraut WH, Simmons RL, and Bauer AJ. Biphasic response to gut manipulation and temporal correlation of cellular infiltrates and muscle dysfunction in rat. Surgery 126: 498-509, 1999.
    • (1999) Surgery , vol.126 , pp. 498-509
    • Kalff, J.C.1    Buchholz, B.M.2    Eskandari, M.K.3    Hierholzer, C.4    Schraut, W.H.5    Simmons, R.L.6    Bauer, A.J.7
  • 18
    • 0032801960 scopus 로고    scopus 로고
    • Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus
    • Kalff JC, Carlos TM, Schraut WH, Billiar TR, Simmons RL, and Bauer AJ. Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus. Gastroenterology 117: 378-387, 1999.
    • (1999) Gastroenterology , vol.117 , pp. 378-387
    • Kalff, J.C.1    Carlos, T.M.2    Schraut, W.H.3    Billiar, T.R.4    Simmons, R.L.5    Bauer, A.J.6
  • 19
    • 0033979825 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents
    • Kalff JC, Schraut WH, Billiar TR, Simmons RL, and Bauer AJ. Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents. Gastroenterology 118: 316-327, 2002.
    • (2002) Gastroenterology , vol.118 , pp. 316-327
    • Kalff, J.C.1    Schraut, W.H.2    Billiar, T.R.3    Simmons, R.L.4    Bauer, A.J.5
  • 20
    • 0032471304 scopus 로고    scopus 로고
    • Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus
    • Kalff JC, Schraut WH, Simmons RL, and Bauer AJ. Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg 228: 652-663, 1998.
    • (1998) Ann Surg , vol.228 , pp. 652-663
    • Kalff, J.C.1    Schraut, W.H.2    Simmons, R.L.3    Bauer, A.J.4
  • 21
    • 0345596440 scopus 로고    scopus 로고
    • Regulation of macrophage eicosanoid generation is dependent on nuclear factor κB
    • Lo CJ, Cryer HG, Fu M, and Lo FR. Regulation of macrophage eicosanoid generation is dependent on nuclear factor κB. J Trauma 45: 19-23, 1998.
    • (1998) J Trauma , vol.45 , pp. 19-23
    • Lo, C.J.1    Cryer, H.G.2    Fu, M.3    Lo, F.R.4
  • 22
    • 0031951375 scopus 로고    scopus 로고
    • Suppression of nitric oxide formation by tyrosine kinase inhibitors in murine N9 microglia
    • Lockhart BP, Cressey KC, and Lepagnol JM. Suppression of nitric oxide formation by tyrosine kinase inhibitors in murine N9 microglia. Br J Pharmacol 123: 879-889, 1998.
    • (1998) Br J Pharmacol , vol.123 , pp. 879-889
    • Lockhart, B.P.1    Cressey, K.C.2    Lepagnol, J.M.3
  • 23
    • 1842295670 scopus 로고    scopus 로고
    • Tyrosine kinase inhibition ameliorates the hyperdynamic state and decreases nitric oxide production in cirrhotic rats with portal hypertension and ascites
    • Lopez-Talavera JC, Levitzki A, Martinez M, Gazit A, Esteban R, and Guardia J. Tyrosine kinase inhibition ameliorates the hyperdynamic state and decreases nitric oxide production in cirrhotic rats with portal hypertension and ascites. J Clin Invest 100: 664-670, 1997.
    • (1997) J Clin Invest , vol.100 , pp. 664-670
    • Lopez-Talavera, J.C.1    Levitzki, A.2    Martinez, M.3    Gazit, A.4    Esteban, R.5    Guardia, J.6
  • 25
    • 0027453552 scopus 로고
    • Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8
    • Matsusaka T, Fujikawa K, Nishio Y, Mukaida N, Matsushima K, Kishimoto T, and Akira S. Transcription factors NF-IL6 and NF-κB synergistically activate transcription of the inflammatory cytokines, interleukin 6 and interleukin 8. Proc Natl Acad Sci USA 90: 10193-10197, 1993.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10193-10197
    • Matsusaka, T.1    Fujikawa, K.2    Nishio, Y.3    Mukaida, N.4    Matsushima, K.5    Kishimoto, T.6    Akira, S.7
  • 26
  • 28
    • 0028343059 scopus 로고
    • Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors
    • Novogrodsky A, Vanichkin A, Patya M, Gazit A, Osherov N, and Levitzki A. Prevention of lipopolysaccharide-induced lethal toxicity by tyrosine kinase inhibitors. Science 264: 1319-1322, 1994.
    • (1994) Science , vol.264 , pp. 1319-1322
    • Novogrodsky, A.1    Vanichkin, A.2    Patya, M.3    Gazit, A.4    Osherov, N.5    Levitzki, A.6
  • 29
    • 0033119065 scopus 로고    scopus 로고
    • Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR
    • Overbergh L, Valckx D, Waer M, and Mathieu C. Quantification of murine cytokine mRNAs using real time quantitative reverse transcriptase PCR. Cytokine 11: 305-312, 1999.
    • (1999) Cytokine , vol.11 , pp. 305-312
    • Overbergh, L.1    Valckx, D.2    Waer, M.3    Mathieu, C.4
  • 30
    • 0002030921 scopus 로고    scopus 로고
    • Physiologic evaluation of colonic motility in awake c-kit-deficient mice and immunofluorescence evaluation of colonic interstitial cells of Cajal
    • edited by Krammer HJ and Singer MV. London: Kluwer Academic
    • Pezzone MA, Fraser MO, Van Bibber MM, and de Groat WC. Physiologic evaluation of colonic motility in awake c-kit-deficient mice and immunofluorescence evaluation of colonic interstitial cells of Cajal. In: Neurogastroenterology-from the Basics to the Clinics, edited by Krammer HJ and Singer MV. London: Kluwer Academic, 2000, p. 461-469.
    • (2000) Neurogastroenterology-from the Basics to the Clinics , pp. 461-469
    • Pezzone, M.A.1    Fraser, M.O.2    Van Bibber, M.M.3    De Groat, W.C.4
  • 31
    • 0030800625 scopus 로고    scopus 로고
    • Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: A possible role for protein tyrosine kinase
    • Ruetten H and Thiemermann C. Effects of tyrphostins and genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase. Br J Pharmacol 122: 59-70, 1997.
    • (1997) Br J Pharmacol , vol.122 , pp. 59-70
    • Ruetten, H.1    Thiemermann, C.2
  • 33
    • 0034668118 scopus 로고    scopus 로고
    • Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: Comparison of endpoint and real-time methods
    • Schmittgen TD, Zakrajsek BA, Mills AG, Gorn V, Singer MJ, and Reed MW. Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. Anal Biochem 285: 194-204, 2000.
    • (2000) Anal Biochem , vol.285 , pp. 194-204
    • Schmittgen, T.D.1    Zakrajsek, B.A.2    Mills, A.G.3    Gorn, V.4    Singer, M.J.5    Reed, M.W.6
  • 36
    • 0030885980 scopus 로고    scopus 로고
    • Patterns of intestinal motility recovery during the early stage following abdominal surgery: Clinical and manometric study
    • Shibata Y, Toyoda S, Nimura Y, and Miyati M. Patterns of intestinal motility recovery during the early stage following abdominal surgery: clinical and manometric study. World J Surg 21: 806-809, 1997.
    • (1997) World J Surg , vol.21 , pp. 806-809
    • Shibata, Y.1    Toyoda, S.2    Nimura, Y.3    Miyati, M.4
  • 37
    • 0036290384 scopus 로고    scopus 로고
    • APC0576, a novel inhibitor of NF-κB-dependent gene activation, prevents pro-inflammatory cytokine-induced chemokine production in human endothelial cells
    • Takehana K, Konishi A, Oonuki A, Noguchi M, Fujita K, Iino Y, and Kobayashi T. APC0576, a novel inhibitor of NF-κB-dependent gene activation, prevents pro-inflammatory cytokine-induced chemokine production in human endothelial cells. Biochem Biophys Res Commun 293: 945-952, 2002.
    • (2002) Biochem Biophys Res Commun , vol.293 , pp. 945-952
    • Takehana, K.1    Konishi, A.2    Oonuki, A.3    Noguchi, M.4    Fujita, K.5    Iino, Y.6    Kobayashi, T.7
  • 38
    • 4243632019 scopus 로고    scopus 로고
    • The inducible nitric oxide synthase (iNOS) gene in leukocyte mediates intestinal dysmotility in murine postoperative ileus
    • Türler A, Kalff JC, Moore BA, Hoffman RA, Billiar TR, Simmons RL, and Bauer AJ. The inducible nitric oxide synthase (iNOS) gene in leukocyte mediates intestinal dysmotility in murine postoperative ileus (Abstract). Gastroenterology 120: A535, 2001.
    • (2001) Gastroenterology , vol.120
    • Türler, A.1    Kalff, J.C.2    Moore, B.A.3    Hoffman, R.A.4    Billiar, T.R.5    Simmons, R.L.6    Bauer, A.J.7
  • 42
    • 0016720165 scopus 로고
    • Postoperative motility of the large intestine in man
    • Wilson JP. Postoperative motility of the large intestine in man. Gut 16: 689-692, 1975.
    • (1975) Gut , vol.16 , pp. 689-692
    • Wilson, J.P.1
  • 43
    • 0026578021 scopus 로고
    • Tyrosine kinase inhibitors and the contractile action of epidermal growth factor-urogastrone and other agonists in gastric smooth muscle
    • Yang SG, Saifeddine M, and Hollenberg MD. Tyrosine kinase inhibitors and the contractile action of epidermal growth factor-urogastrone and other agonists in gastric smooth muscle. Can J Physiol Pharmacol 70: 85-93, 1992.
    • (1992) Can J Physiol Pharmacol , vol.70 , pp. 85-93
    • Yang, S.G.1    Saifeddine, M.2    Hollenberg, M.D.3
  • 44
    • 0034743275 scopus 로고    scopus 로고
    • Effects of NF-κβ1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, 1L-1α-1α, IL-1β and IL-6 mRNA expression in vivo
    • Zhou D, Yu T, Chen G, Brown SA, Yu Z, Mattson MP, and Thompson JS. Effects of NF-κβ1 (p50) targeted gene disruption on ionizing radiation-induced NF-κB activation and TNFα, 1L-1α-1α, IL-1β and IL-6 mRNA expression in vivo. Int J Radiat Biol 77: 763-772, 2001.
    • (2001) Int J Radiat Biol , vol.77 , pp. 763-772
    • Zhou, D.1    Yu, T.2    Chen, G.3    Brown, S.A.4    Yu, Z.5    Mattson, M.P.6    Thompson, J.S.7


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