Regioselective oxidation of N-alkylpyrrolidines to pyrrolidin-5-ones by RuCl3/NaIO4

Tetrahedron Letters

Volumn 45, Issue 7, 2004, Pages 1403-1406

  Sharma, Nagendra K ^a   Ganesh, Krishna N ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

N Alkyl pyrrolidinones; Oxidation; RuCl3 NaIO4

Indexed keywords

CHLORIDE; IODINE DERIVATIVE; OXIDE; PYRROLIDINE DERIVATIVE; RUTHENIUM DERIVATIVE; SODIUM DERIVATIVE;

ARTICLE; OXIDATION; STEREOCHEMISTRY; SYNTHESIS;

EID: 1642538443     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2003.12.072     Document Type: Article

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24. 4 and concentrated to dryness. The crude product was purified by column chromatography to give 5 as a white foam. Yield 30-45%.
25. 2 . Hydrogen atoms were included in the refinement as per the riding model.