Activity of Neutrophil NADPH Oxidase in Iron-Deficient Anemia

Biological Trace Element Research

Volumn 96, Issue 1-3, 2003, Pages 109-115

  Kurtoglu, Erdal ^a   Ugur, Aysegul ^a   Baltaci, Abdulkerim Kasim ^a   Mogolkoc, Rasim ^a   Undar, Levent ^b  

^a SELCUK UNIVERSITY FACULTY OF MEDICINE   (Turkey)

^b AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Iron supplementation; Iron deficiency anemia; NADPH oxidase; Neutrophil function

Indexed keywords

IRON; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; EVALUATION; FEMALE; HUMAN; IRON DEFICIENCY ANEMIA; IRON STORAGE; IRON THERAPY; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; RESPIRATORY BURST;

ANEMIA, IRON-DEFICIENCY; BLOOD BACTERICIDAL ACTIVITY; DIETARY SUPPLEMENTS; HUMANS; IRON; NADPH OXIDASE; NEUTROPHILS; PHAGOCYTOSIS; SPECTROMETRY, FLUORESCENCE; STATISTICS, NONPARAMETRIC;

EID: 1642521008     PISSN: 01634984     EISSN: None     Source Type: Journal    
DOI: 10.1385/BTER:96:1-3:109     Document Type: Article

References (23)

1. K. L. Erickson, E. A. Medina, and N. E. Hubbard, Micronutrients and innate immunity. J. Infect. Dis. 182 (Suppl 1), 5-10 (2000).
2. Iron deficiency, United States, 1999-2000, MMWR 51, 879.
3. E. M. Ross, Evaluation and treatment of iron deficiency in adults, Nutr. Clin. Care. 5, 220-224 (2002).
4. A. Silva, S. Atukorala, I. Weerasinghe, et al., Iron supplementation improves iron status and reduces morbidity in children with or without upper respiratory tract infections: a randomized controlled study in Colombo, Sri Lanka, Am. J. Clin. Nutr. 77(1), 234-241 (2003).
5. T. Gera and H. P. Sachdev, Effect of iron supplementation on incidence of infectious illness in children: systematic review, Br. Med. J. 325(7373), 1142 (2002).
6. M. J. Gonzales, P. P. Rubio, C. J. Cabello, G. Garcia-Casasola, and J. L. Alvarez-Sala, Recurrent infections, severe neutropenia and neutrophil chemotaxis defect in paroxysmal nocturnal hemoglobinuria, Ann. Med. Int. 11(10), 490-492 (1994).
7. J. Parkin and B. Cohen, An overview of the immune system, Lancet 357, 777-789 (2001).
8. F. Van Eden, M. Klut, B. Walker, et al., The use of flow cytometry to measure neutrophil functions, J. Immunol. Methods 232, 23-43 (1999).
9. V. Witko, P. Rieu, B. Descamps, et al., Neutrophils: molecules, functions and patho-physiological aspects. Laboratory investigation 80(5), 617-640 (2000).
10. M. Yagisava, A. Yuo, M. Yonemaru, et al., Superoxide release and NADPH oxidase components in mature human phagocytes, Biochem. Biophys. Res. 228, 510-516 (1996).
11. O. J. Dodd and D. B. Pearse, Effect of the NADPH oxidase inhibitor apocynin on ischemia-reperfusion lung injury, Am. J. Physiol. (Heart Circ. Physiol.) 279, 303-312 (2000).
12. W. Fang, V. Myllys, and M. Sandlom, Resazurin reduction as a function of respiratory burst in bovine neutrophils, Am. J. Vet. Res. 58(6), 601-607 (1997).
13. J. Berger and J. C. Dillon, Control of iron deficiency in developing countries, Sante 12(1), 22-30 (2002).
14. J. Jason, L. K. Archibald, O. C. Nwanyanwu, et al., The effects of iron deficiency on lymphocyte cytokine production and activation: preservation of hepatic iron but not at all cost, Clin. Exp. Immunol. 126(3), 466-473 (2001).
15. A. Hrycek, Z. Kalina, R. Badowski, et al., Spontaneous migration and adherence of leukocytes and the NBT test of oeripheral blood neutrophils in patients with iron deficiency anemia, Acta Haematol. Pol. 22(2), 261-266 (1991).
16. S. M. Hasan, M. Aziz, P. Ahmad, et al., Phagocyte metabolic function in iron deficiency anemia of Indian children, J. Trop. Pediatr. 35(1), 6-9 (1989).
17. H. Turgeon-O'Brien, J. Amiot, L. Lemieux, et al., Myeloperoxidase activity of polymorphonuclear leukocytes in iron deficiency anemia and anemia of chronic disorders, Acta Haemotol. 74(3), 151-154 (1985).
18. Y. Sevgi, C. Gonenc, and A. Cigdem, Neutrophil glutathione peroxidase activity in iron deficiency anemia, Scand. J. Haematol. 36(1), 58-60 (1986).
19. C. Lee, K. Miura, X. Liu, et al., Biphasic regulation of leukocyte superoxide generation by nitric oxide and peroxinitrite, J. Biol. Chem. 15, 38,965-38,972 (2000).
20. J. Doussiere, J. Gaillard, and P. V. Vignais, The heme component of the neutrophil NADPH oxidase complex is a target for aryliodonium compounds, Biochemistry, 38(12), 3694-3703 (1999).
21. - generating flavocytochrome b of neutrophils. Evidence for a transition from a low-spin state of the heme iron component, Biochemistry, 35(41), 13,400-13,410 (1996).
22. R. Ishisaka, T. Kanno, H. Kanematsu, et al., Superoxide dismutase-like activity of metal substituted lactoferrin derivates, Physiol. Chem. Phys. Med. NMR. 30(1), 1-3 (1998).
23. Q. Li, Q. Liao, C. Luo, et al., Investigation of impairment of neutrophil's phagocytosis and bactericidal function in rats with iron deficiency, Hua Xi Yi Ke Da Xue Xue Bao 22(3), 274-277 (1991).