Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesia

Neuroscience

Volumn 88, Issue 2, 1999, Pages 499-506

  MacArthur, L ^a   Ren, K ^a   Pfaffenroth, E ^a   Franklin, E ^a   Ruda, M A ^a  

^a Pain Neurosensory Mechanisms Br N   (United States)

Author keywords

Descending control; Dynorphin; Enkephalin; Inflammation; Nociception; Spinal cord

Indexed keywords

DYNORPHIN;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; INFLAMMATION; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD TRANSSECTION;

ANIMALS; BLOTTING, NORTHERN; CALCITONIN GENE-RELATED PEPTIDE; COLCHICINE; DENERVATION; DYNORPHINS; ENKEPHALINS; FREUND'S ADJUVANT; GANGLIA, SPINAL; GENE EXPRESSION; HYPERALGESIA; INFLAMMATION; MALE; NEURONS, AFFERENT; NOCICEPTORS; PROTEIN PRECURSORS; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD; TACHYKININS;

EID: 0032889948     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(98)00204-8     Document Type: Article

References (30)

1. Basbaum A. I., Fields H. L. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. A. Rev. Neurosci. 7:1984;309-338.
2. Besson J.-M., Chaouch A. Peripheral and spinal mechanisms of nociception. Physiol. Rev. 67:1987;67-186.
3. Cervero F., Schaible H.-G., Schmidt R. F. Tonic descending inhibition of spinal cord neurons driven by joint afferents in normal cats and in cats with an inflamed knee joint. Expl Brain Res. 83:1991;675-678.
4. Chirguin J. M., Przybyla A. E., MacDonald R. J., Rutter N. J. Isolation of biologically active RNA from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
5. Civelli O., Douglass J., Goldstein A., Herbert E. Sequence and expression of the rat prodynorphin gene. Proc. natn. Acad. Sci. U.S.A. 82:1985;4291-4295.
6. Dubner R. (1991) Neuronal plasticity and pain following peripheral tissue inflammation or nerve injury. In Proceedings of the VIth World Congress on Pain (eds Bond M. R., Charlton J. E. and Woolf C. J.), pp. 264-276. Elsevier, Amsterdam.
7. Dubner R., Ruda M. A. Activity-dependent plasticity following tissue injury and inflammation. Trends Neurosci. 15:1992;96-103.
8. Dugaiczyk A., Haron J. A., Stone E. M., Dennison O. E., Rothblum K. N., Schwartz R. J. Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger RNA isolated from chicken muscle. Biochemistry. 22:1983;1605-1613.
9. Duggan A. W., Morton C. R. Tonic descending inhibition and spinal nociceptive transmission. Prog. Brain Res. 77:1988;193-211.
10. Fields H. L., Basbaum A. I. Brainstem control of spinal pain-transmission neurons. A. Rev. Physiol. 40:1978;217-248.
11. Gebhart G. F. (1986) Modulatory effects of descending systems on spinal dorsal horn neurons. In Spinal Afferent Processing (ed. Yaksh T. L.), pp. 391-416. Plenum, New York.
12. Hammond D. L. (1986) Control systems for nociceptive afferent processing: the descending inhibitory pathways. In Spinal Afferent Processing (ed. Yaksh T. L.), pp. 363-390. Plenum, New York.
13. Hargreaves K., Dubner R., Brown F., Flores C., Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain. 32:1988;77-88.
14. Hylden J. L. K., Nahin R. L., Traub R. J., Dubner R. Expansion of receptive fields of spinal lamina I projection neurons in rats with unilateral adjuvant-induced inflammation: the contribution of dorsal horn mechanisms. Pain. 37:1989;229-243.
15. Iadarola M. J., Brady L. S., Draisci G., Dubner R. Enhancement of dynorphin gene expression in spinal cord following experimental inflammation: stimulus specificity, behavioral parameters and opioid receptor binding. Pain. 35:1988;313-326.
16. MacArthur L., Koller K. J., Eiden L. E. Enkephalin gene transcription in bovine chromaffin cells is regulated by calcium and protein kinase A signal transduction pathways: identification of DNase I-hypersensitive sites. Molec. Pharmac. 44:1993;545-551.
17. Millan M. J., Millan M. H., Czlonkowski A., Hollt V., Pilcher C. W., Herz A., Colpaert F. C. A model of chronic pain in the rat: response of multiple opioid systems to adjuvant-induced arthritis. J. Neurosci. 6:1986;899-906.
18. Millan M. J., Czlonkowski A., Morris B., Stein C., Arendt R., Huber A., Hollt V., Herz A. Inflammation of the hind limb as a model of unilateral, localized pain: influence on multiple opioid systems in the spinal cord of the rat. Pain. 35:1988;299-312.
19. Nahin R. L., Hylden J. L. K., Iadarola M. J., Dubner R. Peripheral inflammation is associated with increased dynorphin immunoreactivity in both projection and local circuit neurons in the superficial dorsal horn of the rat lumbar spinal cord. Neurosci. Lett. 96:1989;247-252.
20. Noguchi K., Dubner R., Ruda M. A. Preproenkephalin mRNA in spinal dorsal horn neurons is induced by peripheral inflammation and is co-localized with Fos and Fos-related proteins. Neuroscience. 46:1992;561-570.
21. Ren K., Dubner R. NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpaw. Neurosci. Lett. 163:1993;22-26.
22. Ren K., Dubner R. Enhanced descending modulation of nociception in rats with persistent hindpaw inflammation. J. Neurophysiol. 76:1996;3025-3037.
23. Rigby P. W. J., Dieckmann M., Rhodes C., Berg P. Labelling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase. J. molec. Biol. 113:1977;237-251.
24. Ruda M. A., Iadarola M. J., Cohen L. V., Young W. S. III In situ hybridization histochemistry and immunocytochemistry reveal an increase in spinal dynorphin biosynthesis in a rat model of peripheral inflammation and hyperalgesia. Proc. natn. Acad. Sci. U.S.A. 85:1988;622-626.
25. Ruda M. A., Ren K., Besse D. Regulation of spinal neuropeptide genes in a rat model of peripheral inflammation and hyperalgesia. Prog. Brain Res. 104:1995;349-365.
26. Schaible H.-G., Neugebauer B., Cervero F., Schmidt R. F. Changes in tonic descending inhibition of spinal neurons with articular input during the development of acute arthritis in the cat. J. Neurophysiol. 66:1991;1021-1032.
27. Stamford J. A. Descending control of pain. Br. J. Anaesth. 75:1995;217-227.
28. Traub R. J., Allen B., Humphrey E., Ruda M. A. Ultrastructural analysis of calcitonin gene-related peptide-like immunoreactivity in the cat dorsal spinal cord provides evidence for a multisegmental projection of nociceptive c-fiber primary afferents. J. comp. Neurol. 302:1990;562-574.
29. Willis W. D. Anatomy and physiology of descending control of nociceptive responses of dorsal horn neurons: a comprehensive review. Prog. Brain Res. 77:1988;1-29.
30. Yoshikawa K., Sabol S. L. Glucocorticoids and cyclic AMP synergistically regulate the abundance of preproenkephalin messenger RNA in neuroblastoma-glioma hybrid cells. Biochem. biophys. Res. Commun. 139:1986;1-10.