Estradiol represses prolactin-induced expression of Na+/ taurocholate cotransporting polypeptide in liver cells through estrogen receptor-α and signal transducers and activators of transcription 5a

Endocrinology

Volumn 145, Issue 4, 2004, Pages 1739-1749

  Cao, Jingsong ^a   Wood, Marcie ^a   Liu, Yong ^a   Hoffman, Tim ^a   Hyde, Jim ^a   Park Sarge, Ok Kyong ^a   Vore, Mary ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIESTROGEN; BILE SALT; CARRIER PROTEIN; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FULVESTRANT; MESSENGER RNA; PLACENTA LACTOGEN; PROLACTIN; PROLACTIN RECEPTOR; PROTEIN P300; SODIUM TAUROCHOLATE COTRANSPORTING POLYPEPTIDE; STAT5A PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL TISSUE; ARTICLE; BASOLATERAL MEMBRANE; BILE ACID METABOLISM; BILE ACID TRANSPORT; CELL STRAIN HEPG2; CONTROLLED STUDY; DOSE RESPONSE; ESTRADIOL BLOOD LEVEL; FEMALE; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HORMONAL REGULATION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; LIVER CELL; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPORTER GENE; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; CARRIER PROTEINS; CELL LINE; DNA; DNA-BINDING PROTEINS; ESTRADIOL; ESTROGEN ANTAGONISTS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; HEPATOCYTES; HISTONE ACETYLTRANSFERASES; LIGANDS; MEMBRANE TRANSPORT PROTEINS; MILK PROTEINS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; OVARIECTOMY; PHOSPHORYLATION; PREGNANCY; PROLACTIN; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; RNA, MESSENGER; SHEEP; STAT5 TRANSCRIPTION FACTOR; SYMPORTERS; TRANS-ACTIVATORS; TYROSINE;

EID: 1642505681     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0752     Document Type: Article

References (59)

1. Nathanson MH, Boyer JL 1991 Mechanisms and regulation of bile secretion. Hepatology 14:551-566
2. Hagenbuch B, Stieger B, Foguet M, Lubbert H, Meier PJ 1991 Functional expression cloning and characterization of the hepatocyte Na + /bile acid co-transport system. Proc Natl Acad Sci USA 88:10629-10633
3. Karpen SJ, Sun AQ, Kudish B, Hagenbuch B, Meier PJ, Ananthanarayanan M, Suchy FJ 1996 Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter. J Biol Chem 271:15211-15221
4. Liu Y, Ganguly T, Hyde JF, Vore M 1995 Prolactin increases mRNA encoding Na(+)-TC cotransport polypeptide and hepatic Na(+)-TC cotransport. Am J Physiol 268:G11-G17
5. Liu Y, Hyde JF, Vore M 1992 Prolactin regulates maternal bile secretory function post partum. J Pharmacol Exp Ther 261:560-566
6. Ganguly TC, Liu Y, Hyde JF, Hagenbuch B, Meier PJ, Vore M 1994 Prolactin increases hepatic Na+/taurocholate co-transport activity and messenger RNA post partum. Biochem J 303:33-36
7. Cao J, Huang L, Liu Y, Hoffman T, Stieger B, Meier PJ, Vore M 2001 Differential regulation of hepatic bile salt and organic anion transporters in pregnant and postpartum rats and the role of prolactin. Hepatology 33:140-147
8. Cao J, Gowri PM, Ganguly TC, Wood M, Hyde JF, Talamantes F, Vore M 2001 PRL, placental lactogen, and GH induce Na(+)/taurocholate-cotransporting polypeptide gene expression by activating signal transducer and activator of transcription-5 in liver cells. Endocrinology 142:4212-4222
9. Ganguly TC, O'Brien ML, Karpen SJ, Hyde JF, Suchy FJ, Vore M 1997 Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5. J Clin Invest 99: 2906-2914
10. Ogren L, Talamantes F 1988 Prolactins of pregnancy and their cellular source. Int Rev Cytol 112:1-65
11. Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA 1998 Prolactin (PRL) and its receptor: actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19:225-268
12. Bridges RS 1984 A quantitative analysis of the roles of dosage, sequence, and duration of estradiol and progesterone exposure in the regulation of maternal behavior in the rat. Endocrinology 114:930-940
13. Reyes H, Simon FR 1993 Intrahepatic cholestasis of pregnancy: an estrogen-related disease. Semin Liver Dis 13:289-301
14. Simon FR, Fortune J, Iwahashi M, Gartung C, Wolkoff A, Sutherland E 1996 Ethinyl estradiol cholestasis involves alterations in expression of liver sinusoidal transporters. Am J Physiol 271:G1043-G1052
15. Pettersson K, Gustafsson JA 2001 Role of estrogen receptor β in estrogen action. Annu Rev Physiol 63:165-192
16. Porter LF, Elm MS, Van Thiel DH, Dugas MC, Eagon PK 1983 Characterization and quantitation of human hepatic estrogen receptor. Gastroenterology 84:704-712
17. Gustafsson JA, Mode A, Norstedt G, Eneroth P, Hokfelt T 1983 Central control of prolactin and estrogen receptors in rat liver - expression of a novel endocrine system, the hypothalamo-pituitary-liver axis. Annu Rev Pharmacol Toxicol 23:259-278
18. Katzenellenbogen BS, Choi I, Delage-Mourroux R, Ediger TR, Martini PG, Montano M, Sun J, Weis K, Katzenellenbogen JA 2000 Molecular mechanisms of estrogen action: selective ligands and receptor pharmacology. J Steroid Biochem Mol Biol 74:279-285
19. Laudet V, Hanni C, Coll J, Catzeflis F, Stehelin D 1992 Evolution of the nuclear receptor gene superfamily. EMBO J 11:1003-1013
20. Greene GL, Gilna P, Waterfield M, Baker A, Hort Y, Shine J 1986 Sequence and expression of human estrogen receptor complementary DNA. Science 231:1150-1154
21. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA 1996 Qoning of a novel receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 93:5925-5930
22. Mosselman S, Polman J, Dijkema R 1996 ER β: identification and characterization of a novel human estrogen receptor. FEBS Lett 392:49-53
23. Lieberman BA 1997 The estrogen receptor activity cycle: dependence on multiple protein-protein interactions. Crit Rev Eukaryot Gene Expr 7:43-59
24. Shibata H, Spencer TE, Onate SA, Jenster G, Tsai SY, Tsai MJ, O'Malley BW 1997 Role of co-activators and co-repressors in the mechanism of steroid/ thyroid receptor action. Recent Prog Horm Res 52:141-164
25. Klinge CM 2000 Estrogen receptor interaction with co-activators and co-repressors. Steroids 65:227-251
26. Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138: 863-870
27. Norstedt G, Wrange O, Gustafsson JA 1981 Multihormonal regulation of the estrogen receptor in rat liver. Endocrinology 108:1190-1196
28. Eagon PK, Elm MS, Tadic SD, Nanji AA 2001 Downregulation of nuclear sex steroid receptor activity correlates with severity of alcoholic liver injury. Am J Physiol Gastrointest Liver Physiol 281:G342-G349
29. Kahn D, Zeng Q, Kajani M, Eagon PK, Lai H, Makowka L, Starzl TE, Van Thiel DH 1989 The effect of different types of hepatic injury on the estrogen and androgen receptor activity of liver. J Invest Surg 2:125-133
30. Porter LE, Elm MS, Van Thiel DH, Eagon PK 1987 Hepatic estrogen receptor in human liver disease. Gastroenterology 92:735-745
31. Stoecklin E, Wissler M, Schaetzle D, Pfitzner E, Groner B 1999 Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family. J Steroid Biochem Mol Biol 69:195-204
32. Stocklin E, Wissler M, Gouilleux F, Groner B 1996 Functional interactions between Stat5 and the glucocorticoid receptor. Nature 383:726-728
33. Katzenellenbogen BS 2000 Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways. J Soc Gynecol Investig 7:S33-S37
34. Yamamoto T, Matsuda T, Junicho A, Kishi H, Saatcioglu F, Muraguchi A 2000 Cross-talk between signal transducer and activator of transcription 3 and estrogen receptor signaling. FEBS Lett 486:143-148
35. Faulds MH, Pettersson K, Gustafsson JA, Haldosen LA 2001 Cross-talk between ERs and signal transducer and activator of transcription 5 is E2 dependent and involves two functionally separate mechanisms. Mol Endocrinol 15:1929-1940
36. Gouilleux F, Pallard C, Dusanter-Fourt I, Wakao H, Haldosen LA, Norstedt G, Levy D, Groner B 1995 Prolactin, growth hormone, erythropoietin and granulocyte-macrophage colony stimulating factor induce MGF-Stat5 DNA binding activity. EMBO J 14:2005-2013
37. Wrenn CK, Katzenellenbogen BS 1993 Structure-function analysis of the hormone binding domain of the human estrogen receptor by region-specific mutagenesis and phenotypic screening in yeast. J Biol Chem 268:24089-24098
38. Sambrook J, Russell DW 2001 Molecular cloning, a laboratory manual. 3rd ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press
39. Kalra PS, Kalra SP 1981 Differential effects of low serum levels of estradiol-17β on hypothalamic LHRH levels and LH secretion in castrated male rats. Neuroendocrinology 33:340-346
40. Mann JS, Kindy MS, Hyde JF, Clark MR, Curry Jr TE 1993 Role of protein synthesis, prostaglandins, and estrogen in rat ovarian metalloproteinase inhibitor production. Biol Reprod 48:1006-1013
41. Chomczynski P, Sacchi N 1987 Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 162: 156-159
42. Cao J, Stieger B, Meier PJ, Vore M 2002 Expression of rat hepatic multidrug resistance-associated proteins and organic anion transporters in pregnancy. Am J Physiol Gastrointest Liver Physiol 283:G757-G766
43. Bossard R, Stieger B, O'Neill B, Fricker G, Meier PJ 1993 Ethinylestradiol treatment induces multiple canalicular membrane transport alterations in rat liver. J Clin Invest 91:2714-2720
44. Frasor J, Barkai U, Zhong L, Fazleabas AT, Gibori G 2001 PRL-induced ERα gene expression is mediated by Janus kinase 2 (Jak2) while signal transducer and activator of transcription 5b (Stat5b) phosphorylation involves Jak2 and a second tyrosine kinase. Mol Endocrinol 15:1941-1952
45. Frasor J, Park K, Byers M, Telleria C, Kitamura T, Yu-Lee LY, Djiane J, Park-Sarge OK, Gibori G 2001 Differential roles for signal transducers and activators of transcription 5a and 5b in PRL stimulation of ERα and ERβ transcription. Mol Endocrinol 15:2172-2181
46. Pfitzner E, Jahne R, Wissler M, Stoecklin E, Groner B 1998 p300/CREB-binding protein enhances the prolactin-mediated transcriptional induction through direct interaction with the transactivation domain of Stat5, but does not participate in the Stat5-mediated suppression of the glucocorticoid response. Mol Endocrinol 12:1582-1593
47. Harnish DC, Evans MJ, Scicchitano MS, Bhat RA, Karathanasis SK 1998 Estrogen regulation of the apolipoprotein AI gene promoter through transcription cofactor sharing. J Biol Chem 273:9270-9278
48. Arias J, Alberts AS, Brindle P, Claret FX, Smeal T, Karin M, Feramisco J, Montminy M 1994 Activation of cAMP and mitogen responsive genes relies on a common nuclear factor. Nature 370:226-229
49. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH 1993 Phosphorylated CREB binds specifically to the nuclear protein CBP. Nature 365:855-859
50. Kwok RP, Lundblad JR, ChriviaJC, Richards JP, Bachinger HP, Brennan RG, Roberts SG, Green MR, Goodman RH 1994 Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370:223-226
51. Kamei Y, Xu L, Heinzel T, Torchia J, Kurokawa R, Gloss B, Lin SC, Heyman RA, Rose DW, Glass CK, Rosenfeld MG 1996 A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85:403-414
52. Kurokawa R, Kalafus D, Ogliastro MH, Kioussi C, Xu L, Torchia J, Rosenfeld MG, Glass CK 1998 Differential use of CREB binding protein-coactivator complexes. Science 279:700-703
53. Bhattacharya S, Eckner R, Grossman S, Oldread E, Arany Z, D'Andrea A, Livingston DM 1996 Cooperation of Stat2 and p300/CBP in signalling induced by interferon-α. Nature 383:344-347
54. Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Darnell Jr JE 1996 Two contact regions between Stat1 and CBP/p300 in interferon γ signaling. Proc Natl Acad Sci USA 93:15092-15096
55. Groner B, Gouilleux F 1995 Prolactin-mediated gene activation in mammary epithelial cells. Curr Opin Genet Dev 5:587-594
56. Wyszomierski SL, Yeh J, Rosen JM 1999 Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STAT5 activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. Mol Endocrinol 13:330-343
57. Sueyoshi T, Yokomori N, Korach KS, Negishi M 1999 Developmental action of estrogen receptor-α feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver. Mol Pharmacol 56:473-477
58. Petz LN, Nardulli AM 2000 Sp1 binding sites and an estrogen response element half-site are involved in regulation of the human progesterone receptor A promoter. Mol Endocrinol 14:972-985
59. Anderson I, Gorski J 2000 Estrogen receptor α interaction with estrogen response element half-sites from the rat prolactin gene. Biochemistry 39:3842-3847