Detection and Enumeration of Circulating HIV-1-Specific Memory B Cells in HIV-1-Infected Patients

Journal of Acquired Immune Deficiency Syndromes

Volumn 35, Issue 2, 2004, Pages 114-119

  Fondere, Jean Michel ^a   Huguet, Marie France ^a   Macura Biegun, Anna ^b   Baillat, Vincent ^c   Ohayon, Viviane ^a   Reynes, Jacques ^c   Vendrell, Jean Pierre ^a,d  

^a LAPEYRONIE HOSPITAL   (France)

^b JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^c GUI DE CHAULIAC HOSPITAL   (France)

^d INSERM   (France)

Author keywords

AIDS; Antibodies to HIV 1; Memory B lymphocytes

Indexed keywords

CD19 ANTIGEN; CD27 ANTIGEN; CD40 LIGAND; GAG PROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERLEUKIN 10; INTERLEUKIN 2; POL PROTEIN; VIRUS ENVELOPE PROTEIN; VIRUS PROTEIN;

ARTICLE; B LYMPHOCYTE; CONTROLLED STUDY; FIBROBLAST CULTURE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGLOBULIN PRODUCTION; IMMUNOPHENOTYPING; LYMPHOCYTE COUNT; LYMPHOCYTE CULTURE; MEMORY CELL; POLYCLONAL ACTIVATION; PRIORITY JOURNAL; VIRUS LOAD;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTIBODY SPECIFICITY; ANTIGENS, CD; ANTIGENS, CD27; B-LYMPHOCYTES; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HIV ANTIBODIES; HIV-1; HUMANS; IMMUNOGLOBULIN D; IMMUNOLOGIC MEMORY; VIREMIA;

EID: 1642499257     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/00126334-200402010-00002     Document Type: Article

References (20)

1. Schittek B, Rajewsky K. Maintenance of B-cell memory by long-lived cells generated from proliferating precursors. Nature. 1990;34611:749-751.
2. Banchereau J, Rousset F. Human B lymphocytes: phenotype, proliferation, and differentiation. Adv Immunol. 1992;52:125-262.
3. MacLennan IC, Gulbranson-Judge A, Toellner KM, et al. The changing preference of T and B cells for partners as T-dependent antibody responses develop. Immunol Rev. 1997;156:53-66.
4. Rajewsky K. Burnet's unhappy hybrid. Nature. 1998;394:624-625.
5. Bachmann MF, Kundig TM, Odermatt B, et al. Free recirculation of memory B cells versus antigen-dependent differentiation to antibody-forming cells. J Immunol. 1994;153:3386-3397.
6. De Milito A, Morch C, Sonnerborg A, et al. Loss of memory (CD27) B lymphocytes in HIV-1 infection. AIDS. 2001;15:957-964.
7. Miedema F, Petit AJ, Terpstra FG, et al. Immunological abnormalities in human immunodeficiency virus (HIV)- infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs. J Clin Invest. 1988;82:1908-1914.
8. Lane HC, Masur H, Edgar LC, et al. Abnormalities of B-cell activation and immunoregulation in patients with the acquired immunodeficiency syndrome. N Engl J Med. 1983;309:453-458.
9. Martinez-Maza O, Crabb E, Mitsuyasu RT, et al. Infection with the human immunodeficiency virus (HIV) is associated with an in vivo increase in B lymphocyte activation and immaturity. J Immunol. 1987;138:3720-3724.
10. Amadori A, De Rossi A, Faulkner-Valle GP, et al. Spontaneous in vitro production of virus-specific antibody by lymphocytes from HIV-infected subjects. Clin Immunol Immunopathol. 1988;46:342-351.
11. Berberian L, Goodglick L, Kipps TJ, et al. Immunoglobulin VH3 gene products: natural ligands for HIV gp120. Science. 1993;261:1588-1591.
12. Arpin C, Dechanet J, Van Kooten C, et al. Generation of memory B cells and plasma cells in vitro. Science. 1995;268:720-722.
13. Kindler V, Zubler RH. Memory but not naive, peripheral blood B lymphocytes differentiate into Ig-secreting cells after CD40 ligation and co-stimulation with IL-4 and the differentiation factors IL-2, IL-10, and IL-3. J Immunol. 1997;159:2085-2090.
14. Cordoba F, Lavabre-Bertrand T, Salhi SL, et al. Spontaneous monoclonal immunoglobulin-secreting peripheral blood mononuclear cells as a marker of disease severity in multiple myeloma. Br J Haematol. 2000; 108:549-558.
15. Conge AM, Reynes J, Atoui N, et al. Spontaneous in vitro anti-human immunodeficiency virus type 1 antibody secretion by peripheral blood mononuclear cells is related to disease progression in zidovudine-treated adults. J Infect Dis. 1994;170:1376-1383.
16. Lacascade C, Conge AM, Baillat V, et al. In vitro anti-Toxoplasma gondii antibody production by peripheral blood mononuclear cells in the diagnosis and the monitoring of toxoplasmic encephalitis in AIDS-related brain lesions. J Acquir Immune Defic Syndr. 2000;25:256-260.
17. Binley JM, Klasse PJ, Cao Y, et al. Differential regulation of the antibody responses to Gag and Env proteins of human immunodeficiency virus type 1. J Virol. 1997;71:2799-2809.
18. Vendrell JP, Segondy M, Ducos J, et al. Analysis of the spontaneous in vitro anti-HIV-1 antibody secretion by peripheral blood mononuclear cells in HIV-1 infection. Clin Exp Immunol. 1991;83:197-202.
19. Morris L, Binley JM, Clas BA, et al. HIV-1 antigen-specific and -nonspecific B cell responses are sensitive to combination antiretroviral therapy. J Exp Med. 1998;188:233-245.
20. Fournier AM, Fondere JM, Alix-Panabieres C, et al. Spontaneous secretion of immunoglobulins and anti-HIV-1 antibodies by in vivo activated B lymphocytes from HIV-1-infected subjects: monocyte and natural killer cell requirement for in vitro terminal differentiation into plasma cells. Clin Immunol. 2002;103:98-109.