Pharmacodynamics of in Vivo Nitroglycerin Tolerance in Normal Conscious Rats: Effects of Dose and Dosing Protocol

Pharmaceutical Research

Volumn 21, Issue 1, 2004, Pages 114-120

  Wang, Ellen Q ^a   Balthasar, Joseph P ^a   Fung, Ho Leung ^a  

^a UNIVERSITY AT BUFFALO   (United States)

Author keywords

Dosing protocol; Mean arterial pressure; Modeling; Nitroglycerin tolerance; Pharmacodynamics

Indexed keywords

GLYCERYL TRINITRATE;

ANIMAL EXPERIMENT; ARTERY DILATATION; ARTICLE; BLOOD PRESSURE MONITORING; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE REGIMEN; DRUG MECHANISM; DRUG TOLERABILITY; DRUG TOLERANCE; ENZYME DEGRADATION; IN VIVO STUDY; MALE; MEAN ARTERIAL PRESSURE; MULTIPLE DRUG DOSE; NONHUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT;

ANIMALS; BLOOD PRESSURE; CONSCIOUSNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG TOLERANCE; INFUSIONS, INTRAVENOUS; MALE; MODELS, ANIMAL; MODELS, BIOLOGICAL; MODELS, CHEMICAL; NITROGLYCERIN; RATS; RATS, SPRAGUE-DAWLEY;

EID: 1642457359     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000012158.80991.7e     Document Type: Article

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