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Volumn 28, Issue 3, 1996, Pages 432-438

Sustained antiplatelet properties of nitroglycerin during hemodynamic tolerance in rats

Author keywords

Bleeding time; Cyclic GMP; Nitric oxide; Nitroglycerin; Platelets; Tolerance

Indexed keywords

ANTITHROMBOCYTIC AGENT; CYCLIC GMP; GLYCERYL TRINITRATE; ISOBUTYLMETHYLXANTHINE; KETAMINE; N ACETYL S NITROSOPENICILLAMINE; NITRATE; NITRIC OXIDE; XYLAZINE;

EID: 0029815891     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-199609000-00013     Document Type: Article
Times cited : (19)

References (56)
  • 1
    • 50449195485 scopus 로고
    • Nitroglycerine as a remedy for angina pectoris
    • Murrell E. Nitroglycerine as a remedy for angina pectoris. Lancet 1879;1:80-1.
    • (1879) Lancet , vol.1 , pp. 80-81
    • Murrell, E.1
  • 2
    • 0018826034 scopus 로고
    • Pharmacokinetic-hemodynamic studies of intravenous nitroglycerin in congestive heart failure
    • Armstrong PW, Armstrong J, Marks GS. Pharmacokinetic-hemodynamic studies of intravenous nitroglycerin in congestive heart failure. Circulation 1980;62:160-6.
    • (1980) Circulation , vol.62 , pp. 160-166
    • Armstrong, P.W.1    Armstrong, J.2    Marks, G.S.3
  • 4
    • 0021691605 scopus 로고
    • Intravenous nitroglycerin infusion in acute myocardial infarction: Myocardial salvage
    • Jugdutt BI. Intravenous nitroglycerin infusion in acute myocardial infarction: myocardial salvage. Cardiovasc Res Rep 1984;5:1145-63.
    • (1984) Cardiovasc Res Rep , vol.5 , pp. 1145-1163
    • Jugdutt, B.I.1
  • 5
    • 0014060269 scopus 로고
    • A study of cross-tolerance to circulatory effects of organic nitrates
    • Schelling JL, Lasagna L. A study of cross-tolerance to circulatory effects of organic nitrates. Clin Pharmacol Ther 1967;8:256-60.
    • (1967) Clin Pharmacol Ther , vol.8 , pp. 256-260
    • Schelling, J.L.1    Lasagna, L.2
  • 6
    • 0021081260 scopus 로고
    • Tolerance to isosorbide dinitrate: Rate of development and reversal
    • Parker JO, Fung H-L, Ruggeriello D, Stone JA. Tolerance to isosorbide dinitrate: rate of development and reversal. Circulation 1983;68:1074-80.
    • (1983) Circulation , vol.68 , pp. 1074-1080
    • Parker, J.O.1    Fung, H.-L.2    Ruggeriello, D.3    Stone, J.A.4
  • 7
    • 0025270449 scopus 로고
    • Nitrate patches: Duration of action and loss of efficacy; reflections on the nitrates' mode of action
    • Bussman WD. Nitrate patches: duration of action and loss of efficacy; reflections on the nitrates' mode of action. Eur J Clin Pharmacol 1990;38:s27-9.
    • (1990) Eur J Clin Pharmacol , vol.38
    • Bussman, W.D.1
  • 8
    • 0025373475 scopus 로고
    • Nitrates: Why and how they should be used today?
    • Silber S. Nitrates: why and how they should be used today? Eur J Pharmacol 1990;38:s35-51.
    • (1990) Eur J Pharmacol , vol.38
    • Silber, S.1
  • 9
    • 0015595425 scopus 로고
    • Mechanism of tolerance development to organic nitrates
    • Needleman P, Johnson EM Jr. Mechanism of tolerance development to organic nitrates. J Pharmacol Exp Ther 1973; 184:709-15.
    • (1973) J Pharmacol Exp Ther , vol.184 , pp. 709-715
    • Needleman, P.1    Johnson Jr., E.M.2
  • 10
    • 0027528328 scopus 로고
    • Relationship between nitroglycerin-induced vascular relaxation and nitric oxide production: Probes with inhibitors and tolerance development
    • Chung SJ, Fung H-L. Relationship between nitroglycerin-induced vascular relaxation and nitric oxide production: probes with inhibitors and tolerance development. Biochem Pharmacol 1993;45:257-63.
    • (1993) Biochem Pharmacol , vol.45 , pp. 257-263
    • Chung, S.J.1    Fung, H.-L.2
  • 11
    • 0022979575 scopus 로고
    • Desensitization to nitroglycerin in vascular smooth muscle from rat and human
    • Waldman SA, Rapoport RM, Ginsburg R, Murad F. Desensitization to nitroglycerin in vascular smooth muscle from rat and human. Biochem Pharmacol 1986;35:3525-31.
    • (1986) Biochem Pharmacol , vol.35 , pp. 3525-3531
    • Waldman, S.A.1    Rapoport, R.M.2    Ginsburg, R.3    Murad, F.4
  • 12
    • 0023240541 scopus 로고
    • Prevention and reversal of nitrate tolerance in patients with congestive heart failure
    • Packer M, Lee WH, Kessler PD, Gottlieb SS, Medina N, Yushack M. Prevention and reversal of nitrate tolerance in patients with congestive heart failure. N Engl J Med 1987;317:799-804.
    • (1987) N Engl J Med , vol.317 , pp. 799-804
    • Packer, M.1    Lee, W.H.2    Kessler, P.D.3    Gottlieb, S.S.4    Medina, N.5    Yushack, M.6
  • 13
    • 0025114810 scopus 로고
    • Tolerance to intravenous nitroglycerin in patients with congestive heart failure: Role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine
    • Dupuis J, Lalonde G, Lemieux R, Rouleau JL. Tolerance to intravenous nitroglycerin in patients with congestive heart failure: role of increased intravascular volume, neurohumoral activation and lack of prevention with N-acetylcysteine. J Am Coll Cardiol 1990;16:923-31.
    • (1990) J Am Coll Cardiol , vol.16 , pp. 923-931
    • Dupuis, J.1    Lalonde, G.2    Lemieux, R.3    Rouleau, J.L.4
  • 14
    • 0025747926 scopus 로고
    • Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin
    • Parker JD, Farrell B, Fenton T, Cohanim M, Parker JO. Counter-regulatory responses to continuous and intermittent therapy with nitroglycerin. Circulation 1991;84:2336-45.
    • (1991) Circulation , vol.84 , pp. 2336-2345
    • Parker, J.D.1    Farrell, B.2    Fenton, T.3    Cohanim, M.4    Parker, J.O.5
  • 15
    • 0028799761 scopus 로고
    • Evidence for enhanced vascular Superoxide anion production in nitrate tolerance
    • Munzel T, Sayegh H, Freeman BA, Tarpey MM, Harrison DG. Evidence for enhanced vascular Superoxide anion production in nitrate tolerance. J Clin Invest 1995;95:187-94.
    • (1995) J Clin Invest , vol.95 , pp. 187-194
    • Munzel, T.1    Sayegh, H.2    Freeman, B.A.3    Tarpey, M.M.4    Harrison, D.G.5
  • 16
    • 0029063158 scopus 로고
    • Evidence for the role of endothelin 1 and protein kinase C in nitroglycerin tolerance
    • Munzel T, Giaid A, Kurz S, Stewart DJ, Harrison DG. Evidence for the role of endothelin 1 and protein kinase C in nitroglycerin tolerance. Proc Natl Acad Sci USA 1995;92: 5244-8.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 5244-5248
    • Munzel, T.1    Giaid, A.2    Kurz, S.3    Stewart, D.J.4    Harrison, D.G.5
  • 17
    • 0027205008 scopus 로고
    • Solving the mystery of nitrate tolerance: A new scent on the trail?
    • Fung H-L. Solving the mystery of nitrate tolerance: a new scent on the trail? Circulation 1993;88:322-4.
    • (1993) Circulation , vol.88 , pp. 322-324
    • Fung, H.-L.1
  • 18
    • 0023784348 scopus 로고
    • Reduced thiol and the effect of intravenous nitroglycerin on platelet aggregation
    • Stamler J, Cunningham M, Loscalzo J. Reduced thiol and the effect of intravenous nitroglycerin on platelet aggregation. Am J Cardiol 1988;62:377-80.
    • (1988) Am J Cardiol , vol.62 , pp. 377-380
    • Stamler, J.1    Cunningham, M.2    Loscalzo, J.3
  • 19
    • 0025024067 scopus 로고
    • Effects of nitroglycerin at therapeutic doses on platelet aggregation in unstable angina pectoris and myocardial infarction
    • Diodati J, Theroux P, Latour JG, Lacoste L, Lam JYT, Waters D. Effects of nitroglycerin at therapeutic doses on platelet aggregation in unstable angina pectoris and myocardial infarction. Am J Cardiol 1990;66:683-8.
    • (1990) Am J Cardiol , vol.66 , pp. 683-688
    • Diodati, J.1    Theroux, P.2    Latour, J.G.3    Lacoste, L.4    Lam, J.Y.T.5    Waters, D.6
  • 20
    • 0027513859 scopus 로고
    • Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris
    • Chirkov YY, Naujalis JI, Sage E, Horowitz JD. Antiplatelet effects of nitroglycerin in healthy subjects and in patients with stable angina pectoris. J Cardiovasc Pharmacol 1993; 21:384-9.
    • (1993) J Cardiovasc Pharmacol , vol.21 , pp. 384-389
    • Chirkov, Y.Y.1    Naujalis, J.I.2    Sage, E.3    Horowitz, J.D.4
  • 21
    • 0027322403 scopus 로고
    • Platelet cGMP: A potentially useful indicator to evaluate the effects of nitroglycerin and nitrate tolerance
    • Watanabe H, Kakihana M, OhtsukaS, Enomoto T, Yasui K, Sugishita Y. Platelet cGMP: a potentially useful indicator to evaluate the effects of nitroglycerin and nitrate tolerance. Circulation 1993;88:29-36.
    • (1993) Circulation , vol.88 , pp. 29-36
    • Watanabe, H.1    Kakihana, M.2    Ohtsuka, S.3    Enomoto, T.4    Yasui, K.5    Sugishita, Y.6
  • 23
    • 0027287933 scopus 로고
    • A liposome based platelet substitute, the plateletsome, with hemostatic efficacy
    • Rybak MEM, Renzulli LA. A liposome based platelet substitute, the plateletsome, with hemostatic efficacy. Biomat Artif Celts Immob Biotechnol 1993;21:101-18.
    • (1993) Biomat Artif Celts Immob Biotechnol , vol.21 , pp. 101-118
    • Rybak, M.E.M.1    Renzulli, L.A.2
  • 24
    • 0023889496 scopus 로고
    • Antianginal effects of intravenous nitroglycerin over 24 hours
    • Zimrin D, Reichek N, Bogin KT, et al. Antianginal effects of intravenous nitroglycerin over 24 hours. Circulation 1988; 77:1376-84.
    • (1988) Circulation , vol.77 , pp. 1376-1384
    • Zimrin, D.1    Reichek, N.2    Bogin, K.T.3
  • 25
    • 0025763877 scopus 로고
    • Prevention of nitrate tolerance with angiotensin converting enzyme inhibitors
    • Katz RJ, Levy WS, Buff L, Wasserman AG. Prevention of nitrate tolerance with angiotensin converting enzyme inhibitors. Circulation 1991;83:1271-7.
    • (1991) Circulation , vol.83 , pp. 1271-1277
    • Katz, R.J.1    Levy, W.S.2    Buff, L.3    Wasserman, A.G.4
  • 26
    • 0026630281 scopus 로고
    • Effects of diuretic therapy on the development of tolerance during continuous therapy with nitroglycerin
    • Parker JD, Farrell B, Fenton T, Parker JO. Effects of diuretic therapy on the development of tolerance during continuous therapy with nitroglycerin. J Am Coll Cardiol 1992; 20:616-22.
    • (1992) J Am Coll Cardiol , vol.20 , pp. 616-622
    • Parker, J.D.1    Farrell, B.2    Fenton, T.3    Parker, J.O.4
  • 27
    • 0026523330 scopus 로고
    • Pharmacodynamic and pharmacokinetic evaluation of a new transdermal delivery system with time-dependent release of glyceryl trinitrate
    • Wiegand A, Bauer KH, Trenk D, Jahnchcn E. Pharmacodynamic and pharmacokinetic evaluation of a new transdermal delivery system with time-dependent release of glyceryl trinitrate. J Clin Pharmacol 1992;32:77-84.
    • (1992) J Clin Pharmacol , vol.32 , pp. 77-84
    • Wiegand, A.1    Bauer, K.H.2    Trenk, D.3    Jahnchcn, E.4
  • 28
    • 0023603599 scopus 로고
    • Tolerance to relaxation in rat aorta: Comparison of an S-nitrosothiol with nitroglycerin
    • Kowaluk EA, Poliszczuk R, Fung H-L. Tolerance to relaxation in rat aorta: comparison of an S-nitrosothiol with nitroglycerin. Eur J Pharmacol 1987;144:379-83.
    • (1987) Eur J Pharmacol , vol.144 , pp. 379-383
    • Kowaluk, E.A.1    Poliszczuk, R.2    Fung, H.-L.3
  • 29
    • 0025020554 scopus 로고
    • Dissociation of nitrovasodilator-induced relaxation from cGMP levels in vitro nitrate tolerance
    • Kowaluk EA, Fung H-L. Dissociation of nitrovasodilator-induced relaxation from cGMP levels in vitro nitrate tolerance. Eur J Pharmacol 1990;176:91-5.
    • (1990) Eur J Pharmacol , vol.176 , pp. 91-95
    • Kowaluk, E.A.1    Fung, H.-L.2
  • 30
    • 0025977848 scopus 로고
    • Differential hemodynamic effects of and tolerance properties of nitroglycerin and 5-nitrosothiol in experimental heart failure
    • Bauer JA, Fung H-L. Differential hemodynamic effects of and tolerance properties of nitroglycerin and 5-nitrosothiol in experimental heart failure. J Pharmacol Exp Ther 1991; 256:249-54.
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 249-254
    • Bauer, J.A.1    Fung, H.-L.2
  • 31
    • 0023758976 scopus 로고
    • Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation and guanylate cyclase activation by glyceryl trinitrate and enantiomers of isoidide dinitrate
    • Bennett BM, Schoder H, Hayward LD, Waldman SA, Murad F. Effect of in vitro organic nitrate tolerance on relaxation, cyclic GMP accumulation and guanylate cyclase activation by glyceryl trinitrate and enantiomers of isoidide dinitrate. Circ Res 1988;63:693-701.
    • (1988) Circ Res , vol.63 , pp. 693-701
    • Bennett, B.M.1    Schoder, H.2    Hayward, L.D.3    Waldman, S.A.4    Murad, F.5
  • 32
    • 0028902255 scopus 로고
    • Dissociation of tissue thiol content from nitroglycerin induced cyclic-3′,5′-guanosine monophosphate and the state of tolerance: In vivo experiments
    • Haj-Yehia A, Benet LZ. Dissociation of tissue thiol content from nitroglycerin induced cyclic-3′;,5′-guanosine monophosphate and the state of tolerance: in vivo experiments. J Pharmacol Exp Ther 1995;273:94-100.
    • (1995) J Pharmacol Exp Ther , vol.273 , pp. 94-100
    • Haj-Yehia, A.1    Benet, L.Z.2
  • 33
    • 10144222019 scopus 로고
    • Persistent anti-thrombotic effects of continuous nitroglycerin therapy despite hemodynamic tolerance
    • Hebert D, Lam JYT, Walters D. Persistent anti-thrombotic effects of continuous nitroglycerin therapy despite hemodynamic tolerance. Circulation 1993;88:1-347.
    • (1993) Circulation , vol.88 , pp. 1-347
    • Hebert, D.1    Lam, J.Y.T.2    Walters, D.3
  • 34
    • 10144243358 scopus 로고
    • Absence of rebound thrombosis after cessation of continuous nitroglycerin treatment
    • Hebert D, Lam JYT, Moura A. Absence of rebound thrombosis after cessation of continuous nitroglycerin treatment. Circulation 1994;90:I-28.
    • (1994) Circulation , vol.90
    • Hebert, D.1    Lam, J.Y.T.2    Moura, A.3
  • 35
    • 0020692910 scopus 로고
    • Intravenous nitroglycerin in the treatment of spontaneous angina pectoris: A prospective, randomized trial
    • Curfman GD, Heinsimer JA, Lozner EC, Fung H-L. Intravenous nitroglycerin in the treatment of spontaneous angina pectoris: a prospective, randomized trial. Circulation 1983; 67:276-82.
    • (1983) Circulation , vol.67 , pp. 276-282
    • Curfman, G.D.1    Heinsimer, J.A.2    Lozner, E.C.3    Fung, H.-L.4
  • 36
    • 0027184248 scopus 로고
    • Direct inhibition of platelet function by organic nitrates via nitric oxide formation
    • Weber AA, Strobach H, Schror K. Direct inhibition of platelet function by organic nitrates via nitric oxide formation. Eur J Pharmacol 1993;247:29-37.
    • (1993) Eur J Pharmacol , vol.247 , pp. 29-37
    • Weber, A.A.1    Strobach, H.2    Schror, K.3
  • 37
    • 0028788144 scopus 로고
    • Human endothelial cells bioactivate organic nitrates to nitric oxide: Implications for the reinforcement of endothelial defence mechanisms
    • Feelisch M, Brands F, Kelm M. Human endothelial cells bioactivate organic nitrates to nitric oxide: implications for the reinforcement of endothelial defence mechanisms. Eur J Clin Invest 1995;25:737-45.
    • (1995) Eur J Clin Invest , vol.25 , pp. 737-745
    • Feelisch, M.1    Brands, F.2    Kelm, M.3
  • 39
    • 0023976675 scopus 로고
    • Biology of disease. the pathogenesis of atherosclerosis: Atherogenesis and inflammation
    • Munro JM, Cotran RS, Biology of disease. The pathogenesis of atherosclerosis: atherogenesis and inflammation. Lab Invest 1988;58:249-61.
    • (1988) Lab Invest , vol.58 , pp. 249-261
    • Munro, J.M.1    Cotran, R.S.2
  • 40
    • 0017690997 scopus 로고
    • The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits: Smooth muscle cell proliferation and re-endothelialization
    • Friedman RJ, Stemerman MB, Wenz B, et al. The effect of thrombocytopenia on experimental arteriosclerotic lesion formation in rabbits: smooth muscle cell proliferation and re-endothelialization. J Clin Invest 1977;60:1191.
    • (1977) J Clin Invest , vol.60 , pp. 1191
    • Friedman, R.J.1    Stemerman, M.B.2    Wenz, B.3
  • 41
    • 0024510747 scopus 로고
    • Cardiac and vascular effects of atrial natriuretic factor and sodium nitroprusside in healthy men
    • Roy LF, Ogilvie RI, Larochelle P, Hamet P, Leenen FHH. Cardiac and vascular effects of atrial natriuretic factor and sodium nitroprusside in healthy men. Circulation 1989:79:383-92.
    • (1989) Circulation , vol.79 , pp. 383-392
    • Roy, L.F.1    Ogilvie, R.I.2    Larochelle, P.3    Hamet, P.4    Leenen, F.H.H.5
  • 42
    • 0028027071 scopus 로고
    • Plasma arteriovenous cGMP difference as a useful indicator of nitrate tolerance in patients with heart failure
    • Tsutamoto T, Kinoshita M, Ohbayashi Y, Wada A, Maeda Y, Aadachi T. Plasma arteriovenous cGMP difference as a useful indicator of nitrate tolerance in patients with heart failure. Circulation 1990;90:823-9.
    • (1990) Circulation , vol.90 , pp. 823-829
    • Tsutamoto, T.1    Kinoshita, M.2    Ohbayashi, Y.3    Wada, A.4    Maeda, Y.5    Aadachi, T.6
  • 43
    • 0025122129 scopus 로고
    • Effect of molsidimine on ex vivo platelet aggregation and plasma guanosine 3′:5′-cyclic monophosphate levels in healthy volunteers
    • Karrenbrock R, Heim JM, Gerzer R. Effect of molsidimine on ex vivo platelet aggregation and plasma guanosine 3′:5′-cyclic monophosphate levels in healthy volunteers. Klin Wochenschr 1990;68:213-7.
    • (1990) Klin Wochenschr , vol.68 , pp. 213-217
    • Karrenbrock, R.1    Heim, J.M.2    Gerzer, R.3
  • 44
    • 0021949752 scopus 로고
    • Atrial natriuretic factor activates mammalian participate guanylate cyclase
    • Gerzer R, Tremblay J, Pang S, DeLean A, Hamet P. Atrial natriuretic factor activates mammalian participate guanylate cyclase. Fed Proc 1985;44:698.
    • (1985) Fed Proc , vol.44 , pp. 698
    • Gerzer, R.1    Tremblay, J.2    Pang, S.3    DeLean, A.4    Hamet, P.5
  • 45
    • 0011155218 scopus 로고
    • Heat-stable enterotoxin of Escherichia coli: In vitro effects on guanylate cyclase activity, cyclic GMP concentration and ion transport in small intestine
    • Field M, Graf LH, Laird WJ, Smith PL. Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration and ion transport in small intestine. Proc Natl Acad Sci USA 1978;75:2800-4.
    • (1978) Proc Natl Acad Sci USA , vol.75 , pp. 2800-2804
    • Field, M.1    Graf, L.H.2    Laird, W.J.3    Smith, P.L.4
  • 47
    • 0027422217 scopus 로고
    • New bleeding time devices with retractable blades evaluated in children, healthy volunteers and patients with prolonged bleeding time
    • Lethagen S, Kling S. New bleeding time devices with retractable blades evaluated in children, healthy volunteers and patients with prolonged bleeding time. Thromb Haemost 1993;70:595-7.
    • (1993) Thromb Haemost , vol.70 , pp. 595-597
    • Lethagen, S.1    Kling, S.2
  • 48
    • 0028096962 scopus 로고
    • Bleeding time and bleeding: An analysis of the relationship of the bleeding time test with parameters of surgical bleeding
    • De Caterina R, Lanza M, Manca G, Strata GB, Maffei S, Salvatore L. Bleeding time and bleeding: an analysis of the relationship of the bleeding time test with parameters of surgical bleeding. Blood 1994;84:3363-70.
    • (1994) Blood , vol.84 , pp. 3363-3370
    • De Caterina, R.1    Lanza, M.2    Manca, G.3    Strata, G.B.4    Maffei, S.5    Salvatore, L.6
  • 49
    • 72949135166 scopus 로고
    • The role of red cells in haemostasis: The relation between haematocrit, bleeding time and platelet adhesiveness
    • Hellem AJ, Borchgrevink CF, Ames SB. The role of red cells in haemostasis: the relation between haematocrit, bleeding time and platelet adhesiveness. Br J Haematol 1961;7:42-50.
    • (1961) Br J Haematol , vol.7 , pp. 42-50
    • Hellem, A.J.1    Borchgrevink, C.F.2    Ames, S.B.3
  • 50
    • 0015525988 scopus 로고
    • The bleeding time as a screening test for evaluation of platelet function
    • Harker LA, Slichter SJ. The bleeding time as a screening test for evaluation of platelet function. N Engl J Med 1972; 287:155-9.
    • (1972) N Engl J Med , vol.287 , pp. 155-159
    • Harker, L.A.1    Slichter, S.J.2
  • 52
    • 0028269329 scopus 로고
    • Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model
    • Suehiro A, Oura Y, Ueda M, Kakishita E. Correlation between bleeding time and antithrombotic effect of platelet-suppressive agents in rat experimental model. Res Commun Chem Pathol Pharmacol 1994;83:157-63.
    • (1994) Res Commun Chem Pathol Pharmacol , vol.83 , pp. 157-163
    • Suehiro, A.1    Oura, Y.2    Ueda, M.3    Kakishita, E.4
  • 53
    • 0029127945 scopus 로고
    • Aspirin therapy: Optimized platelet inhibition with different loading and maintenance doses
    • Buerke M, Pittroff W, Meyer J, Darius H. Aspirin therapy: optimized platelet inhibition with different loading and maintenance doses. Am Heart J 1995;130:465-72.
    • (1995) Am Heart J , vol.130 , pp. 465-472
    • Buerke, M.1    Pittroff, W.2    Meyer, J.3    Darius, H.4
  • 54
    • 0021894113 scopus 로고
    • Dose-related prolongation of the bleeding time by intravenous nitroglycerin
    • Lichtenthal PR, Rossi E, Louis G, et al. Dose-related prolongation of the bleeding time by intravenous nitroglycerin. Anesth Analg 1985;64:30-3.
    • (1985) Anesth Analg , vol.64 , pp. 30-33
    • Lichtenthal, P.R.1    Rossi, E.2    Louis, G.3
  • 56
    • 0027286545 scopus 로고
    • NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties
    • Keaney JF, Simon DI, Stamler JS, et al. NO forms an adduct with serum albumin that has endothelium-derived relaxing factor-like properties. J Clin Invest 1993;91:1582-9.
    • (1993) J Clin Invest , vol.91 , pp. 1582-1589
    • Keaney, J.F.1    Simon, D.I.2    Stamler, J.S.3


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