Genetic evidence for the existence of two pathways for the biosynthesis of methionine in the Leptospira spp

FEMS Microbiology Letters

Volumn 225, Issue 2, 2003, Pages 257-262

  Picardeau, Mathieu ^a   Bauby, Hélène ^a   Saint Girons, Isabelle ^a  

^a INSTITUT PASTEUR   (France)

Author keywords

Direct sulfhydrylation; Leptospira; Methionine; Transsulfuration

Indexed keywords

ACYLTRANSFERASE; BACTERIAL PROTEIN; HOMOSERINE ACETYLTRANSFERASE; HOMOSERINE O-ACETYLTRANSFERASE; LYASE; MET17 PROTEIN, S CEREVISIAE; METHIONINE; MULTIENZYME COMPLEX; O ACETYLHOMOSERINE (THIOL) LYASE; O-ACETYLHOMOSERINE (THIOL)-LYASE; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CHEMISTRY; ESCHERICHIA COLI; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION; GENETICS; LEPTOSPIRA; LEPTOSPIRA INTERROGANS; METABOLISM; MOLECULAR GENETICS; OPERON; SEQUENCE HOMOLOGY; AMINO ACID SYNTHESIS; BACTERIAL GENE; BACTERIAL STRAIN; CONTROLLED STUDY; GENE DISRUPTION; GENE LOCUS; HOMOLOGOUS RECOMBINATION; LEPTOSPIRA MEYERI; METW GENE; METX GENE; METY GENE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS;

ACETYLTRANSFERASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; CARBON-OXYGEN LYASES; ESCHERICHIA COLI; GENETIC COMPLEMENTATION TEST; LEPTOSPIRA; LEPTOSPIRA INTERROGANS; METHIONINE; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; MUTAGENESIS, INSERTIONAL; OPERON; SACCHAROMYCES CEREVISIAE PROTEINS; SEQUENCE HOMOLOGY;

ENTEROBACTERIACEAE; ESCHERICHIA COLI; GAMMAPROTEOBACTERIA; LEPTOSPIRA; LEPTOSPIRA INTERROGANS; LEPTOSPIRA MEYERI; PROTEOBACTERIA; SPIROCHAETALES;

EID: 1642389429     PISSN: 03781097     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1097(03)00529-9     Document Type: Article

References (16)

1. Greene, R.C. (1996) Biosynthesis of Methionine. Escherichia coli and Salmonella: Cellular and Molecular Biology, 2nd edn., pp. 542-560
2. Foglino M., Borne F., Bally M., Patte J.C. A direct sulhydrylation pathway is used for methionine biosynthesis in Pseudomonas aeruginosa. Microbiology. 141:1995;431-439
3. Belfaiza J., Martel A., Margarita D., Saint Girons I. Direct sulfhydrylation for methionine biosynthesis in Leptospira meyeri. J. Bacteriol. 180:1998;250-255
4. Hwang B.J., Yeom H.J., Kim Y., Lee H.S. Corynebacterium glutamicum utilizes both transsulfuration and direct sulfhydrylation pathways for methionine biosynthesis. J. Bacteriol. 184:2002;1277-1286
5. Auger S., Yuen W.H., Danchin A., Martin-Vertraete I. The metIC operon involved in methionine biosynthesis in Bacillus subtilis is controlled by transcription antitermination. Microbiology. 148:2002;507-518
6. Vermeij P., Kertesz M.A. Pathways of assimilative sulfur metabolism in Pseudomonas putida. J. Bacteriol. 181:1999;5833-5837
7. Alaminos M., Ramos J.L. The methionine biosynthetic pathway from homoserine in Pseudomonas putida involves the metW, metX, metZ, metH and metE gene products. Arch. Microbiol. 176:2001;151-154
8. Ellinghausen H.C., McCullough W.G. Nutrition of Leptospira pomona and growth of 13 other serotypes: fractionation of oleic albumin complex and a medium of bovine albumin and polysorbate 80. Am. J. Vet. Res. 26:1965;45-51
9. Johnson R.C., Harris V.G. Differentiation of pathogenic and saprophytic leptospires. J. Bacteriol. 94:1967;27-31
10. Picardeau M., Brenot A., Saint Girons I. First evidence for gene replacement in Leptospira spp. Inactivation of L. biflexa flaB results in non-motile mutants deficient in endoflagella. Mol. Microbiol. 40:2001;189-199
11. Bauby H., Saint Girons I., Picardeau M. Construction and complementation of the first auxotrophic mutant in the spirochaete Leptospira meyeri. Microbiology. 149:2003;689-693
12. Tchamedeu Kameni A.P., Couture-Tosi E., Saint-Girons I., Picardeau M. Inactivation of the spirochete recA gene results in a mutant with low viability and irregular nucleoid morphology. J. Bacteriol. 184:2002;452-458
13. Prod'hom G., Lagier B., Pelicic V., Hance A.J., Gicquel B., Guilhot C. A reliable amplification technique for the characterization of genomic DNA sequences flanking insertion sequences. FEMS Microbiol. Lett. 158:1998;75-81
14. Andersen G.L., Beattie G.A., Lindow S.E. Molecular characterization and sequence of a methionine biosynthetic locus from Pseudomonas syringae. J. Bacteriol. 180:1998;4497-4507
15. Ren S. etal. Unique and physiological and pathogenic features of Leptospira interrogans revealed by whole genome sequencing. Nature. 422:2003;888-893
16. Alexander F.W., Sandmeier E., Mehta P.K., Christen P. Evolutionary relationships among pyridoxal-5′-phosphate-dependant enzymes, region-specific alpha, beta and gamma families. Eur. J. Biochem. 219:1994;953-960