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Volumn 126, Issue 10, 2004, Pages 3022-3023

Rational Design of A Supra C-1027: Kinetically Stabilized Analogue of the Antitumor Enediyne Chromoprotein

Author keywords

[No Author keywords available]

Indexed keywords

ALKENYLDIALKYNE DERIVATIVE; ANTIBIOTIC C 1027; ANTINEOPLASTIC AGENT; DOUBLE STRANDED DNA; NATURAL PRODUCT; UNCLASSIFIED DRUG;

EID: 1642300604     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja039635z     Document Type: Article
Times cited : (15)

References (24)
  • 8
    • 0004275799 scopus 로고    scopus 로고
    • Maeda, H., Edo, K., Ishida, N., Eds.; Springer: Tokyo
    • For recent reviews on chromoprotein antibiotics and other enediyne natural products, see: (a) Neocarzinostatin; Maeda, H., Edo, K., Ishida, N., Eds.; Springer: Tokyo, 1997.
    • (1997) Neocarzinostatin
  • 9
    • 0000283004 scopus 로고    scopus 로고
    • Barton, D. H. R., Nakanishi, K., Eds.; Elsevier: New York
    • (b) Xi, Z.; Goldberg, I. H. In Comprehensive Natural Products Chemistry; Barton, D. H. R., Nakanishi, K., Eds.; Elsevier: New York, 1999; Vol. 7, p 553.
    • (1999) Comprehensive Natural Products Chemistry , vol.7 , pp. 553
    • Xi, Z.1    Goldberg, I.H.2
  • 20
    • 0141707096 scopus 로고    scopus 로고
    • Thorson reported the self-resistance protein for calicheamicin and the degradation mechanism of the protein by enediyne. Biggins, J. B.; Onwueme, K. C.; Thorson, J. S. Science 2003, 301, 1537-1541.
    • (2003) Science , vol.301 , pp. 1537-1541
    • Biggins, J.B.1    Onwueme, K.C.2    Thorson, J.S.3
  • 21
    • 0025774650 scopus 로고    scopus 로고
    • Isotope effects on the DNA cleavage by the enediynes have been reported. Neocarzinostatin: Frank, B. L.; Worth, L., Jr.; Christner, D. F.; Kozarich, J. W.; Stubbe, J.; Kappen, L. S.; Goldberg, I. H. J. Am. Chem. Soc. 1991, 113, 2271-2275. Calicheamicin: Hangeland, J. J.; De Voss, J. J.; Heath, J. A.; Townsend, C. A.; Ding, W.; Ashcroft, J. S.; Ellestad, G. A. J. Am. Chem. Soc. 1992, 114, 9200-9202. C-1027: see ref 6c.
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 2271-2275
    • Frank, B.L.1    Worth Jr., L.2    Christner, D.F.3    Kozarich, J.W.4    Stubbe, J.5    Kappen, L.S.6    Goldberg, I.H.7
  • 22
    • 0025774650 scopus 로고    scopus 로고
    • Isotope effects on the DNA cleavage by the enediynes have been reported. Neocarzinostatin: Frank, B. L.; Worth, L., Jr.; Christner, D. F.; Kozarich, J. W.; Stubbe, J.; Kappen, L. S.; Goldberg, I. H. J. Am. Chem. Soc. 1991, 113, 2271-2275. Calicheamicin: Hangeland, J. J.; De Voss, J. J.; Heath, J. A.; Townsend, C. A.; Ding, W.; Ashcroft, J. S.; Ellestad, G. A. J. Am. Chem. Soc. 1992, 114, 9200-9202. C-1027: see ref 6c.
    • (1992) J. Am. Chem. Soc. , vol.114 , pp. 9200-9202
    • Hangeland, J.J.1    De Voss, J.J.2    Heath, J.A.3    Townsend, C.A.4    Ding, W.5    Ashcroft, J.S.6    Ellestad, G.A.7
  • 23
    • 0025774650 scopus 로고    scopus 로고
    • C-1027: see ref 6c
    • Isotope effects on the DNA cleavage by the enediynes have been reported. Neocarzinostatin: Frank, B. L.; Worth, L., Jr.; Christner, D. F.; Kozarich, J. W.; Stubbe, J.; Kappen, L. S.; Goldberg, I. H. J. Am. Chem. Soc. 1991, 113, 2271-2275. Calicheamicin: Hangeland, J. J.; De Voss, J. J.; Heath, J. A.; Townsend, C. A.; Ding, W.; Ashcroft, J. S.; Ellestad, G. A. J. Am. Chem. Soc. 1992, 114, 9200-9202. C-1027: see ref 6c.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.