Use of 19F NMR spectroscopy to screen chemical libraries for ligands that bind to proteins

Organic and Biomolecular Chemistry

Volumn 2, Issue 5, 2004, Pages 725-731

  Tengel, Tobias ^a   Fex, Tomas ^b,c   Emtenäs, Hans ^a   Almqvist, Fredrik ^a   Sethson, Ingmar ^a   Kihlberg, Jan ^a,c  

^a UMEÅ UNIVERSITY   (Sweden)

^b Orbichem AB   (Sweden)

^c ASTRAZENECA R AND D   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

FLUORINE COMPOUNDS; MACROMOLECULES; PHARMACOKINETICS; PROTEINS; SURFACE PLASMON RESONANCE; TITRATION;

BINDING STRENGTHS; BIOORGANIC CHEMISTRY; CHEMICAL LIBRARIES; CHEMICAL SHIFTS; HUMAN SERUM ALBUMIN; LIGANDS; MEDICINAL CHEMISTRY;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

BACTERIA (MICROORGANISMS);

BACTERIAL PROTEIN; FLUORINE; LIGAND; SERUM ALBUMIN;

ARTICLE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROTEIN BINDING;

BACTERIAL PROTEINS; BINDING SITES; COMBINATORIAL CHEMISTRY TECHNIQUES; FLUORINE; HUMANS; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PROTEIN BINDING; SERUM ALBUMIN;

EID: 1642296510     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b313166a     Document Type: Article

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