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Volumn 52, Issue 62, 2005, Pages 530-536

Oxidative stress in chronic hepatitis C: A preliminary study on the protective effects of antioxidant flavonoids

Author keywords

Antioxidants; Flavonoids; Hepatitis C; Interferon; Oxidative stress; Ribavirin; Sustained response

Indexed keywords

AMINOTRANSFERASE; ANTIOXIDANT; ANTIOXIDANT BIOFACTOR; FLAVONOID; HERBACEOUS AGENT; PEGINTERFERON ALPHA2B; PLACEBO; RIBAVIRIN; SUPEROXIDE; UNCLASSIFIED DRUG;

EID: 16344394565     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (27)

References (44)
  • 6
    • 0028339240 scopus 로고
    • Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis
    • Shimoda R, Nagashima M, Sakamoto M, Yamaguchi N, Hirohashi S, Yokota J, Kasai H: Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. Cancer Res 1994; 54:3171-3172.
    • (1994) Cancer Res , vol.54 , pp. 3171-3172
    • Shimoda, R.1    Nagashima, M.2    Sakamoto, M.3    Yamaguchi, N.4    Hirohashi, S.5    Yokota, J.6    Kasai, H.7
  • 7
    • 0035055699 scopus 로고    scopus 로고
    • DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: Validation in an open population study
    • Cardin R, Saccoccio G, Masutti F, Bellentani S, Farinati F, Tiribelli C: DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: validation in an open population study. J Hepatol 2001; 34:587-592.
    • (2001) J Hepatol , vol.34 , pp. 587-592
    • Cardin, R.1    Saccoccio, G.2    Masutti, F.3    Bellentani, S.4    Farinati, F.5    Tiribelli, C.6
  • 8
    • 1842408925 scopus 로고    scopus 로고
    • The effects of interferon alpha on serum lipid peroxidation and total thiol content in patients with chronic active hepatitis C
    • Mutlu-Türkoglu U, Ademoglu E, Türkoglu S, Badur S, Uysal M, Toker G: The effects of interferon alpha on serum lipid peroxidation and total thiol content in patients with chronic active hepatitis C. Res Commun Mol Pathol Pharmacol 1997; 96:357-361.
    • (1997) Res Commun Mol Pathol Pharmacol , vol.96 , pp. 357-361
    • Mutlu-Türkoglu, U.1    Ademoglu, E.2    Türkoglu, S.3    Badur, S.4    Uysal, M.5    Toker, G.6
  • 9
    • 0031088467 scopus 로고    scopus 로고
    • Reduced glutathione concentration in erythrocytes of patients with chronic viral hepatitis
    • Swietek K, Juszczyk J: Reduced glutathione concentration in erythrocytes of patients with chronic viral hepatitis. J Viral Hepat 1997; 4:139-141.
    • (1997) J Viral Hepat , vol.4 , pp. 139-141
    • Swietek, K.1    Juszczyk, J.2
  • 11
    • 0030743306 scopus 로고    scopus 로고
    • Increase of resting superoxide anion in the whole blood of patients with decompensated liver cirrhosis
    • Chen M-F, Mo L-R, Lin R-C, Kuo J-Y, Chang K-K, Liao C, Lu F-J: Increase of resting superoxide anion in the whole blood of patients with decompensated liver cirrhosis. Free Radic Biol Med 1997; 23:672-679.
    • (1997) Free Radic Biol Med , vol.23 , pp. 672-679
    • Chen, M.-F.1    Mo, L.-R.2    Lin, R.-C.3    Kuo, J.-Y.4    Chang, K.-K.5    Liao, C.6    Lu, F.-J.7
  • 14
    • 0028006359 scopus 로고
    • Reactive oxygen species, chromosome mutation and cancer: Possible role of clastogenic factors in carcinogenesis
    • Emerit I: Reactive oxygen species, chromosome mutation and cancer: possible role of clastogenic factors in carcinogenesis. Free Radic Biol Med 1994; 16:99-109.
    • (1994) Free Radic Biol Med , vol.16 , pp. 99-109
    • Emerit, I.1
  • 15
    • 0029800785 scopus 로고    scopus 로고
    • Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase
    • Emerit I, Garban F, Vassy J, Filipe P, Freitas J: Superoxide-mediated clastogenesis and anticlastogenic effects of exogenous superoxide dismutase. Proc Natl Acad Sci USA 1996; 93:12799-12804.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 12799-12804
    • Emerit, I.1    Garban, F.2    Vassy, J.3    Filipe, P.4    Freitas, J.5
  • 16
    • 0007441974 scopus 로고    scopus 로고
    • Clastogenic factors as biomarkers of oxidative stress. Their usefulness for evaluation of the efficacy of antioxidant treatment
    • Özben T (Ed.). New York: Plenum Press
    • Emerit I: Clastogenic factors as biomarkers of oxidative stress. Their usefulness for evaluation of the efficacy of antioxidant treatment. In: Özben T (Ed.). Free Radicals, Oxidative Stress and Antioxidants. New York: Plenum Press, 1998; pp. 375-384.
    • (1998) Free Radicals, Oxidative Stress and Antioxidants , pp. 375-384
    • Emerit, I.1
  • 17
    • 0027444755 scopus 로고
    • N-acetyl cysteine enhances the response to interferon-alpha in chronic hepatitis C: A pilot study
    • Beloqui O, Prieto J, Suarez M, Gil B, Qian CH, Garcia, N: N-acetyl cysteine enhances the response to interferon-alpha in chronic hepatitis C: A pilot study. J Interferon Res 1993; 13:279-282.
    • (1993) J Interferon Res , vol.13 , pp. 279-282
    • Beloqui, O.1    Prieto, J.2    Suarez, M.3    Gil, B.4    Qian, C.H.5    Garcia, N.6
  • 18
    • 0032080212 scopus 로고    scopus 로고
    • Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon alpha with and without supplementation with N-acetyl cysteine
    • Bernhard M.C, Junker E, Hettinger A, Lauterburg BH: Time course of total cysteine, glutathione and homocysteine in plasma of patients with chronic hepatitis C treated with interferon alpha with and without supplementation with N-acetyl cysteine. J Hepatol 1998; 28:751-755.
    • (1998) J Hepatol , vol.28 , pp. 751-755
    • Bernhard, M.C.1    Junker, E.2    Hettinger, A.3    Lauterburg, B.H.4
  • 19
    • 0030854425 scopus 로고    scopus 로고
    • A pilot study of the effects of alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C
    • Houglum K, Venkataramani A, Lyche K, Chojkier M: A pilot study of the effects of alpha-tocopherol on hepatic stellate cell activation in chronic hepatitis C. Gastroenterology 1997; 113:1069-1973.
    • (1997) Gastroenterology , vol.113 , pp. 1069-1973
    • Houglum, K.1    Venkataramani, A.2    Lyche, K.3    Chojkier, M.4
  • 20
    • 0031460937 scopus 로고    scopus 로고
    • Vitamin E improves the aminotransferase status of patients suffering from viral hepatitis C: A randomised double-blind, placebo-controlled study
    • Von Herbay A, Stahl W, Niederau C, Sies H: Vitamin E improves the aminotransferase status of patients suffering from viral hepatitis C: a randomised double-blind, placebo-controlled study. Free Radic Res 1997; 27:599-605.
    • (1997) Free Radic Res , vol.27 , pp. 599-605
    • Von Herbay, A.1    Stahl, W.2    Niederau, C.3    Sies, H.4
  • 21
    • 0034280764 scopus 로고    scopus 로고
    • Association of alpha-interferon and acetyl cysteine in patients with chronic hepatitis C
    • Neri S, Terna D, Antoci S, Campanile E, D'Amico RA, Noto R: Association of alpha-interferon and acetyl cysteine in patients with chronic hepatitis C. Panminerva Med 2000; 42:187-192.
    • (2000) Panminerva Med , vol.42 , pp. 187-192
    • Neri, S.1    Terna, D.2    Antoci, S.3    Campanile, E.4    D'Amico, R.A.5    Noto, R.6
  • 23
    • 0025044868 scopus 로고
    • Clastogenic factors: Detection and assay
    • Emerit I: Clastogenic factors: Detection and assay. Methods Enzymol 1990; 186:555-564.
    • (1990) Methods Enzymol , vol.186 , pp. 555-564
    • Emerit, I.1
  • 24
    • 0000877330 scopus 로고
    • Assay for serum lipid peroxide level and its clinical significance
    • Yagi K (Ed.). New York: Academic Press
    • Yagi K: Assay for serum lipid peroxide level and its clinical significance. In: Yagi K (Ed.). Lipid peroxidation. New York: Academic Press, 1988; pp. 223-242.
    • (1988) Lipid Peroxidation , pp. 223-242
    • Yagi, K.1
  • 25
    • 0028283301 scopus 로고
    • Measurement of protein thiol groups and glutathione in plasma
    • Hu M: Measurement of protein thiol groups and glutathione in plasma. Methods Enzymol 1994; 233:380-385.
    • (1994) Methods Enzymol , vol.233 , pp. 380-385
    • Hu, M.1
  • 27
    • 0026072529 scopus 로고
    • Classification of chronic viral hepatitis: A need for reassessment
    • Scheuer PJ: Classification of chronic viral hepatitis: a need for reassessment. J Hepatol 1991; 13:372-374.
    • (1991) J Hepatol , vol.13 , pp. 372-374
    • Scheuer, P.J.1
  • 29
    • 0027283967 scopus 로고
    • Genistein is an effective stimulator of the hormone-binding globulin production in hepatocarcinoma cells in culture
    • Mousavi Y, Adlercreutz H: Genistein is an effective stimulator of the hormone-binding globulin production in hepatocarcinoma cells in culture. Steroids 1993; 58:301-304.
    • (1993) Steroids , vol.58 , pp. 301-304
    • Mousavi, Y.1    Adlercreutz, H.2
  • 31
    • 0030815950 scopus 로고    scopus 로고
    • Oxidative stress-related clastogenic factors in plasma from Chernobyl liquidators: Protective effects of antioxidant plant phenols, vitamins and oligoelements
    • Emerit I, Oganesian N, Arutyunian R, Pogossian A, Sarkisian T, Cernjavski L, Levy A, Feingold J: Oxidative stress-related clastogenic factors in plasma from Chernobyl liquidators: protective effects of antioxidant plant phenols, vitamins and oligoelements. Mutat Res 1997; 377:139-246.
    • (1997) Mutat Res , vol.377 , pp. 139-246
    • Emerit, I.1    Oganesian, N.2    Arutyunian, R.3    Pogossian, A.4    Sarkisian, T.5    Cernjavski, L.6    Levy, A.7    Feingold, J.8
  • 33
    • 0032008339 scopus 로고    scopus 로고
    • Milk thistle (Silybum marinum) for the therapy of liver diseases
    • Flora K, Hahn M, Rosen H, Brenner, K: Milk thistle (Silybum marinum) for the therapy of liver diseases. Am J Gastroenterol 1996; 93:139-143.
    • (1996) Am J Gastroenterol , vol.93 , pp. 139-143
    • Flora, K.1    Hahn, M.2    Rosen, H.3    Brenner, K.4
  • 34
    • 0027992226 scopus 로고
    • Scavenging of reactive oxygen species by silibinin hemisuccinate
    • Mira L, Silva M, Manso CF: Scavenging of reactive oxygen species by silibinin hemisuccinate. Biochem Pharmacol 1994; 48:753-759.
    • (1994) Biochem Pharmacol , vol.48 , pp. 753-759
    • Mira, L.1    Silva, M.2    Manso, C.F.3
  • 37
    • 0028247953 scopus 로고
    • Recent advances in the study of antioxidative effects of Chinese medicinal plants
    • Liu J, Xiao PG: Recent advances in the study of antioxidative effects of Chinese medicinal plants. Phytotherapy Res 1994; 8:445-451.
    • (1994) Phytotherapy Res , vol.8 , pp. 445-451
    • Liu, J.1    Xiao, P.G.2
  • 38
    • 0034572785 scopus 로고    scopus 로고
    • Clinical and pharmacological studies on liver diseases treated with Kampo herbal medicine
    • Cyong JC, Kim SM, Iijima KBL, Kobayashi T, Furuya M: Clinical and pharmacological studies on liver diseases treated with Kampo herbal medicine. Am J Chinese Med 2000; 28:351-360.
    • (2000) Am J Chinese Med , vol.28 , pp. 351-360
    • Cyong, J.C.1    Kim, S.M.2    Iijima, K.B.L.3    Kobayashi, T.4    Furuya, M.5
  • 39
    • 0035008526 scopus 로고    scopus 로고
    • Herbal and complementary and alternative medicine therapies for liver disease
    • Cohen, MR: Herbal and complementary and alternative medicine therapies for liver disease. Clin Liver Dis 2001; 2:461-478.
    • (2001) Clin Liver Dis , vol.2 , pp. 461-478
    • Cohen, M.R.1
  • 40
    • 0032857259 scopus 로고    scopus 로고
    • Epidemiology and review of complementary/alternative medicine treatments
    • Patrick L: Hepatitis C. Epidemiology and review of complementary/ alternative medicine treatments. Alternative Med Review 1999; 4:220-238.
    • (1999) Alternative Med Review , vol.4 , pp. 220-238
    • Patrick, L.1    Hepatitis, C.2
  • 41
    • 0032875149 scopus 로고    scopus 로고
    • Herbal products for liver diseases: A therapeutic challenge for the new millennium
    • Schuppan D, Jia JD, Brinkhaus B, Hahn EG: Herbal products for liver diseases: a therapeutic challenge for the new millennium. Hepatology 1999; 30:1099-1104.
    • (1999) Hepatology , vol.30 , pp. 1099-1104
    • Schuppan, D.1    Jia, J.D.2    Brinkhaus, B.3    Hahn, E.G.4
  • 44
    • 0029859861 scopus 로고    scopus 로고
    • Oxidative damage and fibrinogenesis
    • Poli, G, Parola M: Oxidative damage and fibrinogenesis. Free Radic Biol Med 1997; 22:287-305.
    • (1997) Free Radic Biol Med , vol.22 , pp. 287-305
    • Poli, G.1    Parola, M.2


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