The effects of interferon-α on serum lipid peroxidation and total thiol content in patients with chronic active hepatitis-c

Research Communications in Molecular Pathology and Pharmacology

Volumn 96, Issue 3, 1997, Pages 357-361

  Mutlu Turkoglu U ^a   Ademoglu, E ^a   Turkoglu S ^a   Badur, S ^a   Uysal, M ^a   Taker, G ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON;

ADULT; ANTIOXIDANT ACTIVITY; ARTICLE; CHRONIC ACTIVE HEPATITIS; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HEPATITIS C; HUMAN; LIPID PEROXIDATION; LIVER FUNCTION; MALE; PRIORITY JOURNAL;

ADULT; CHRONIC DISEASE; FEMALE; GLUTATHIONE PEROXIDASE; HEPATITIS C; HUMANS; INTERFERON-ALPHA; LIPID PEROXIDATION; MALE; MIDDLE AGED; OXIDATIVE STRESS; SULFHYDRYL COMPOUNDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

EID: 1842408925     PISSN: 10780297     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Avissar N, Whitin JC, Allen PZ, Wagner DD, Liegey P and Cohen HJ (1989). Biol Chem 264: 15850-15855
2. Beloqui O, Prieto J, Suarez M, Gil B, Qian C H, Garcia N and Civeira M P. (1993) N-Acetyl cysteine enhances the responce to interferon-α in chronic hepatitis C. J ýnterferon Res 13: 279-282
3. Davis G L, Balart L A, Schiff E R, Lindsay K, Bodenheimer H C Jr, Perrilo R P, Carey W, Jacobson I R, Payne J, Dienstag J L, VanThiel D H, Tamburro C, Lefkowitch J, Albrecht J, Meschievitz C, Ortego T J, Gibas A, and The Hepatitis International Therapy Group. (1989) Treatment of chronic hepatitis C with recombinant interferon alpha. N Engl J Med: 321: 1501-1506
4. Di Bisceglie A M, Martin P, Kassianides C, Lisker-Melman M, Murray L, Waggoner J, Goodman Z, Banks S M and Hoofnagle J H. (1989) Recombinant interferon alpha therapy for chronic hepatitis C. N Eng J Med. 321: 1506-1510
5. Farinati F, Cardin R, De Maria N, Libera G D, Marafin C, Lecis E, Burra P, Floreani A, Cecchetto A and Naccarato R. (1995) Iron storage, lipid peroxidation and glutathione turnover in chronic-HCV positive hepatitis J Hepatol 22: 449-456
6. Guechot J, Loria A, Serfaty L, Giral P, Gioudeau J and Poupon R. (1995) Serum hyaluronan as a marker of liver fibrosis in chronic viral hepatitis C: Effect of α-interferon therapy. J Hepatol 22: 22-26
7. Hawkes W C, Craig A. (1990) Automated continuous-flow colorimetric determination of glutathione peroxidase with dichloroindophenol. Anal Biochem 186: 46-52
8. Higueras V, Raya A, Rodrigo J M, Serra M A, Roma J, Romero F J. (1994) Interferon decreases serum lipid peroxidation products of hepatitis C patients. Free Rad Biol Med: 16: 131-133
9. Hu M L. (1994) Measurement of protein thiol groups and glutathione in plasma. Method Enzymol 233: 380-385
10. Koretz R L, Stone O, Mousa M, Gitninck G L. (1985) Non-A, non-B posttransfusion hepatitis-a decade later. Gastroentorology, 88: 1251-1254
11. Lim HL, Myers BM, Hamilton BA, Davis GL and Lau JYN. (1995) Plasma glutathione concentration in patients with chronic hepatitis C virus infection. J Viral Hepatitis 2: 211-214
12. Maeda H and Akaike T. (1991) Oxygen free radicals as pathogenic molecules in viral diseases Proc Soc Exp Biol Med 198: 721-727
13. Navati R, Thiers V, D'Arminio Monforte A et al., (1992) Mother to child transmission of hepatitis C virus detected by nested polymerase chain reaction. J Infect Dis 165: 720-723
14. Sedlak J and Lindsay R H. (1968) Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissues with Ellman's reagent. Anal Biochem 25, 192
15. Sunde RA. (1990) Molecular biology of selenoproteins. Annu Rev Nutr 10: 451-74
16. Thomas J A, Poland B, Honzatko R. (1995) Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation. Arch Biochem Biophys 319: 1-9
17. Thomson B J, Doran M, Lever A M L, Webster A D B. (1987) Alpha-interferon therapy for non-A, non-B hepatitis transmitted by gammaglobulin replacement therapy. Lancet, 1: 539-541.
18. Togashi H, Shinzawa H, Wakabayashi H, Nakamura T, Yamada N, Takahashi T and Ishikawa M. (1990) Activities of free oxygen radical scavenger enzymes in human liver. J Hepatol 11: 200-205
19. Yoshioka T, Kawada K, Shimada T, Mori M. (1979). Am J Obstet Gynecol 135: 372-376.