Switching the sorting mode of membrane proteins from cotranslational endoplasmic reticulum targeting to posttranslational mitochondrial import

Molecular Biology of the Cell

Volumn 16, Issue 4, 2005, Pages 1788-1799

  Miyazaki, Emi ^a   Kida, Yuichiro ^a,b   Mihara, Katsuyoshi ^a   Sakaguchi, Masao ^a,b,c  

^a KYUSHU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ISOPROTEIN; MEMBRANE PROTEIN; PROTEIN;

ANIMAL CELL; ARTICLE; CELL FREE SYSTEM; CELL SELECTION; ENDOPLASMIC RETICULUM; HYDROPHILICITY; HYDROPHOBICITY; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROCESSING; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; COS CELLS; ENDOPLASMIC RETICULUM; MEMBRANE PROTEINS; MICE; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; PROTEIN BIOSYNTHESIS; PROTEIN ISOFORMS; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; SOLUBILITY; SUBSTRATE SPECIFICITY;

EID: 16344387139     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.E04-08-0707     Document Type: Article

References (28)

1. Corral-Debrinski, M., Blugeon, C., and Jacq, C. (2000). In yeast, the 3′ untranslated region or the presequence of ATM1 is required for the exclusive localization of its mRNA to the vicinity of mitochondria. Mol. Cell. Biol. 20, 7881-7892.
2. Eilers, M., and Schatz, G. (1986). Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria. Nature 322, 228-232.
3. Fukuda, M., Aruga, J., Niinobe, M., Aimoto, S., and Mikoshiba, K. (1994). Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II. J. Biol. Chem. 269, 29206-29211.
4. Graf, S. A., Haigh, S. E., Corson, E. D., and Shirihai, O. S. (2004). Targeting, import, and dimerization of a mammalian mitochondrial ATP binding cassette (ABC) transporter, ABCB10 (ABCme). J. Biol. Chem. 279, 42954-42963.
5. Horie, C., Suzuki, H., Sakaguchi, M., and Mihara, K. (2002). Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membrane. Mol. Biol. Cell 13, 1615-1625.
6. Horton, R. M., Ho, S. N., Pullen, J. K., Hunt, H. D., Cai, Z., and Pease, L. R. (1993). Gene splicing by overlap extension. Methods Enzymol. 217, 270-279.
7. Jackson, R. J., and Hunt, T. (1983). Preparation and use of nuclease-treated rabbit reticulocyte lysates for the translation of eukaryotic messenger RNA. Methods Enzymol. 96, 50-74.
8. Johnson, A. E., and van Waes, M. A. (1999). The translocon: a dynamic gateway at the ER membrane. Annu. Rev. Cell Dev. Biol. 15, 799-842.
9. Kanaji, S., Iwahashi, J., Kida, Y., Sakaguchi, M., and Mihara, K. (2000). Characterization of the signal that directs Torn20 to the mitochondrial outer membrane. J. Cell Biol. 151, 277-288.
10. Keenan, R. J., Freymann, D. M., Stroud, R. M., and Walter, P. (2001). The signal recognition particle. Annu. Rev. Biochem. 70, 755-775.
11. Kida, Y., Sakaguchi, M., Fukuda, M., Mikoshiba, K., and Mihara, K. (2000). Membrane topogenesis of a type I signal-anchor protein, mouse synaptotagmin II, on the endoplasmic reticulum. J. Cell Biol. 150, 719-730.
12. Kyte, J., and Doolittle, R. F. (1982). A simple method for displaying the hydropathic character of a protein. J. Mol. Biol. 157, 105-132.
13. Marc, P., Margeot, A., Devaux, P., Blugeon, C., Corral-Debrinski, M., and Jacq, C. (2002). Genome-wide analysis of mRNAs targeted to yeast mitochondria. EMBO Rep. 3, 159-164.
14. Margeot, A., Blugeon, C., Sylvestre, J., Vialette, S., Jacq, C., and Corral-Debrinski, M. (2002). In Saccharomyces cerevisiae, ATP2 mRNA sorting to the vicinity of mitochondria is essential for respiratory function. EMBO J 21, 6893-6904.
15. Miyazaki, E., Sakaguchi, M., Wakabayashi, S., Shigekawa, M., and Mihara, K. (2001). NHE6 protein possesses a signal peptide destined for endoplasmic reticulum membrane and localizes in secretory organelles of the cell. J. Biol. Chem. 276, 49221-49227.
16. Nakamura, Y., Suzuki, H., Sakaguchi, M., and Mihara, K. (2004). Targeting and assembly of rat mitochondrial translocase of outer membrane 22 (TOM22) into the TOM complex. J. Biol. Chem. 279, 21223-21232.
17. Ota, K., Sakaguchi, M., Hamasaki, N., and Mihara, K. (2000). Membrane integration of the second transmembrane segment of band 3 requires a closely apposed preceding signal-anchor sequence. J. Biol. Chem. 275, 29743-29748.
18. Ota, K., Sakaguchi, M., von Heijne, G., Hamasaki, N., and Mihara, K. (1998). Forced transmembrane orientation of hydrophilic polypeptide segments in multispanning membrane proteins. Mol. Cell 2, 495-503.
19. Popov, M., Tam, L. Y., Li, J., and Reithmeier, R.A.F. (1997). Mapping the ends of transmembrane segments in a polytopic membrane protein. J. Biol. Chem. 272, 18325-18332.
20. Sakaguchi, M. (1997). Mutational analysis of signal-anchor and stop-transfer sequences in membrane proteins. In: Membrane protein assembly, ed. G. von Heijne, Austin, TX: R.G. Landes Company, 135-150.
21. Sakaguchi, M., Hachiya, N., Mihara, K., and Omura, T. (1992). Mitochondrial porin can be translocated across both endoplasmic reticulum and mitochondrial membranes. J. Biochem. 112, 243-248.
22. Schmitt, L., and Tampe, R. (2002). Structure and mechanism of ABC transporters. Curr. Opin. Struct. Biol. 12, 754-760.
23. Shirihai, O. S., Gregory, T., Yu, C., Orkin, S. H., and Weiss, M. J. (2000). ABC-me: a novel mitochondrial transporter induced by GATA-1 during erythroid differentiation. EMBO J. 19, 2492-2502.
24. Siegel, V., and Walter, P. (1988). Each of the activities of signal recognition particle (SRP) is contained within a distinct domain: analysis of biochemical mutants of SRP. Cell 52, 39-49.
25. Ukaji, K., Ariyoshi, N., Sakaguchi, M., Hamasaki, N., and Mihara, K. (2002). Membrane topogenesis of the three amino-terminal transmembrane segments of glucose-6-phosphatase on endoplasmic reticulum. Biochem. Biophys. Res. Commun. 292, 153-160.
26. Walter, P., and Blobel, G. (1983). Preparation of microsomal membranes for co-translational protein translocation. Methods Enzymol. 96, 84-93.
27. Weiner, M. P., Costa, G. L., Schoettlin, W., Cline, J., Mathur, E., and Bauer, J. C. (1994). Site-directed mutagenesis of double-stranded DNA by the polymerase chain reaction. Gene 151, 119-123.
28. Yano, M., Kanazawa, M., Terada, K., Namchai, C., Yamaizumi, M., Hanson, B., Hoogenraad, N., and Mori, M. (1997). Visualization of mitochondrial protein import in cultured mammalian cells with green fluorescent protein and effects of overexpression of the human import receptor Tom20. J. Biol. Chem. 272, 8459-8465.