Association of the -159C/T polymorphism of the endotoxin receptor (CD14) with carotid artery disease and cardiovascular mortality in dialysis patients

Blood Purification

Volumn 23, Issue 2, 2005, Pages 128-133

  Losito, Attilio ^a,c   Kalidas, Kamini ^b   Santoni, Stefania ^a   Errico, Rosa ^a   Jeffery, Steve ^b  

^a POLICLINICO MONTELUCE   (Italy)

^b ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^c NONE   (Italy)

Author keywords

Atherosclerosis; Endotoxin; Hemodialysis

Indexed keywords

CD14 ANTIGEN; ENDOTOXIN; PYRIMIDINE NUCLEOTIDE;

AGED; ARTICLE; ATHEROGENESIS; CARDIOVASCULAR RISK; CAROTID ARTERY DISEASE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; DIALYSIS; DISEASE ASSOCIATION; DNA POLYMORPHISM; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HEMODIALYSIS; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RISK ASSESSMENT;

AGED; AGED, 80 AND OVER; ANTIGENS, CD14; CAROTID ARTERY DISEASES; CASE-CONTROL STUDIES; DIALYSIS; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; SURVIVAL ANALYSIS;

EID: 16344362908     PISSN: 02535068     EISSN: None     Source Type: Journal    
DOI: 10.1159/000083207     Document Type: Article

References (21)

1. Foley R, Parfrey PS, Sarnak MJ: Clinical epidemiology of cardiovascular disease in chronic renal disease. Am J Kidney Dis 1998;32(suppl 3):S112-S119.
2. Maeda N, Sawayama Y, Tatsukawa M, Okada K, Furusyo N, Shigematsu M, Kashiwagi S, Hayashi J: Carotid artery lesions and atherosclerotic risk factors in Japanese hemodialysis patients. Atherosclerosis 2003;169:183-192.
3. Zimmermann J, Herrlinger S, Pruy A, Metzger T, Wanner C: Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 1999;55:648-658.
4. Stenvinkel P, Barany P, Heimbürger O, Pecoits-Filho R, Lindholm B: Mortality, malnutrition, and atherosclerosis in ESRD: What is the role of interleukin-6? Kidney Int 2002;61(suppl 80):S103-S108.
5. Lonneman G, Beheme TC, Lenzner B, Floege J, Schulze M, Colton CK, Koch KM, Shaldon S: Permeability of dialyzer membranes to TNF-α-inducing substances derived from water bacteria. Kidney Int 1992;42:61-68.
6. Port FK, Van De Kerkhove KM, Kunkel SL, Kluger MJ: The role of dialysate in the stimulation of interleukin-1 production during clinical hemodialysis. Am J Kidney Dis 1987;10:118-122.
7. Ulevitch R, Tobias PS: Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu Rev Immunol 1995;13:437-457.
8. Baldini M, Lohman IC, Halonen M, Ericson RP, Holt PG, Martinez F: A polymorphism in the 5′ flanking region of the CD14 gene is associated with circulating soluble CD14 levels and with total serum immunoglobulin E. Am J Respir Cell Mol Biol 1999;20:976-983.
9. Wiedermann CJ, Kiechl S, Dunzendorfer S, Schratzberger P, Egger G, Oberhollenzer F, Willeit J: Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: prospective results from the Bruneck study. J Am Coll Cardiol 1999;34:1975-1981.
10. Daugirdas JT: Second generation logarithmic estimates of single-pool variable volume Kt/V: an analysis of error. J Am Soc Nephrol 1993;4:1205-1213.
11. Chobanian AV, Bakris GL, Black HR, Cushman WC, Green LA, Izzo JL Jr, Jones DW, Materson BJ, Oparil S, Wright JT, Roccella EJ, the National High Blood Pressure Education Program Coordinating Committee: The seventh report of the joint national committee on prevention, evaluation and treatment of high blood pressure. JAMA 2003;289:2560-2572.
12. Losito A Fagugli RM, Zampi I, Parente B, de Rango P, Giordano G, Cao PG: Comparison of target organ damage in renovascular and essential hypertension. Am J Hypertens 1996;9:1062-1067.
13. Keberle M, Jenett M, Beissert M, Jahns R Haerten R, Hahan D: Three-dimensional power Doppler sonography in screening for carotid artery disease. J Clin Ultrasound 2000;28:441-451.
14. Tartière JM, Henry OF, Safar H, Bureau JM, Girerd X, Safar ME, Blacher J: Carotid intima-media thickness and carotid and/or iliofemoral plaques: Comparison of two markers of cardiovascular risk in hypertensive patients. J Hypertens 2003;21:739-746.
15. Becker BN, Himmelfarb J, Heinrich WL, Hakim RM: Reassessing the cardiac risk profile in chronic hemodialysis patients: A hypothesis on the role of oxidant stress and other non-traditional cardiac risk factors. J Am Soc Nephrol 1997;8:475-486.
16. Losito A, Kalidas K, Santoni S, Ceccarelli L, Jeffery S: Polymorphism of the renin-angiotensin system genes in dialysis patients association with cerebrovascular disease. Nephrol Dial Transplant 2002;17:2184-2188.
17. Miyazaki H, Matsuoka H, Itabe H et al: Hemodialysis impairs endothelial function via oxidative stress. Effects of vitamin E-coated dialyzer. Circulation 2000;101:1002-1006.
18. Hiki N, Berger D, Dentener M A, Mimura Y, Buurman WA, Prigl C, Seildelmann M, Tsuji E, Kaminishi M, Beger HG: Changes in endotoxin-bending proteins during major elective surgery: important role for soluble CD14 in regulation of biological activity of systemic endotoxin. Clin Diagn Lab Immunol 1999;6:844-850.
19. Nockher WA, Scherberich JE: Monocyte cell-surface CD14 expression and soluble CD14 antigen in hemodialysis: Evidence for chronic exposure to LPS. Kidney Int 1995;48:1469-1476.
20. Risley P, Jerrard-Dunne P, Sitzer M, Buehler A, von Kegler S, Markus HS: Promoter polymorphism in the endotoxin receptor (CD14) is associated with increased carotid atherosclerosis only in smokers: The Carotid Atherosclerosis Progression Study. Stroke 2003;34:600-604.
21. Koenig W, Khuseyinova N, Hoffmann MM, Marz W, Frohlich M, Hoffmeister A, Brenner H, Rothenbacher D: CD14 C(-260): T polymorphism, plasma levels of soluble endotoxin receptor CD14, their association with chronic infections and risk of stable coronary artery disease. J Am Coll Cardiol 2002;40:34-42.