Enhancement of dissolution rate of rofecoxib using solid dispersions with urea

Drug Development Research

Volumn 63, Issue 4, 2004, Pages 181-189

  Liu, Chengsheng ^a   Desai, Kashappa Goud H ^b   Liu, Chenguang ^b   Park, Hyun J ^b  

^a OCEAN UNIVERSITY OF CHINA   (China)

^b Korea University   (South Korea)

Author keywords

Dissolution rate; MDT; Rofecoxib; Solid dispersion; Solubility; Urea

Indexed keywords

DRUG CARRIER; MACROGOL 4000; MANNITOL; POVIDONE; POVIDONE K30; ROFECOXIB; UNCLASSIFIED DRUG; UREA; WATER;

AMORPHOUS STATE; ARTICLE; CONCENTRATION (PARAMETERS); DIFFERENTIAL SCANNING CALORIMETRY; DISPERSION; DISSOLUTION; DRUG FORMULATION; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; ENERGY TRANSFER; FUSION METHOD; GIBBS FREE ENERGY; INFRARED SPECTROSCOPY; MEAN DISSOLUTION TIME; PHYSICAL CHEMISTRY; SCANNING ELECTRON MICROSCOPY; SOLID; SOLID DISPERSION; SOLUBILIZATION; TECHNIQUE; X RAY DIFFRACTION;

EID: 16344362340     PISSN: 02724391     EISSN: None     Source Type: Journal    
DOI: 10.1002/ddr.10412     Document Type: Article

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