Drug presentation to T cells [5] (multiple letters)

Journal of Allergy and Clinical Immunology

Volumn 115, Issue 4, 2005, Pages 876-877

  Naisbitt, Dean John ^a   Pirmohamed, Munir ^a   Park, Brian Kevin ^a   Roujeau, Jean Claude ^b   Wolkenstein, Pierre ^b   Bensussan, Armand ^b  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

SULFAMETHOXAZOLE;

AEROBIC METABOLISM; CELL ACTIVITY; CELL CULTURE; CELL STIMULATION; CLINICAL TRIAL; COVALENT BOND; DATA ANALYSIS; HUMAN; LETTER; PNEUMOCYSTIS PNEUMONIA; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION;

EID: 16244413595     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2005.01.011     Document Type: Letter

References (5)

1. A. Nassif A. Bensussan L. Boumsell A. Deniaud H. Moslehi P. Wolkenstein Toxic epidermal necrolysis: effector cells are drug-specific cytotoxic T-cells J Allergy Clin Immunol 114 2004 1209 1215
2. D.J. Naisbitt J. Farrell S.F. Gordon J.L. Maggs C. Burkhart W.J. Pichler Covalent binding of the nitroso metabolite of sulfamethoxazole leads to toxicity and major histocompatibility complex-restricted antigen presentation Mol Pharmacol 62 2002 628 637
3. B. Schnyder C. Burkhart K. Schnyder-Frutig S. von Greyerz D.J. Naisbitt M. Pirmohamed Recognition of sulfamethoxazole and its reactive metabolites by drug-specific CD4+ T cells from allergic individuals J Immunol 164 2000 6647 6654
4. J. Farrell D.J. Naisbitt N.S. Drummond J.P. Depta F.J. Vilar M. Pirmohamed Characterization of sulfamethoxazole and sulfamethoxazole metabolite-specific T-cell responses in animals and humans J Pharmacol Exp Ther 306 2003 229 237
5. O.B. Engler I. Strasser D.J. Naisbitt A. Cerny W.J. Pichler A chemically inert drug can stimulate T cells in vitro by their T cell receptor in non-sensitised individuals Toxicology 197 2004 47 56